Results 61 to 70 of about 172,705 (282)

The use of clamping grips and friction pads by tree frogs for climbing curved surfaces [PDF]

open access: yes, 2017
Most studies on the adhesive mechanisms of climbing animals have addressed attachment against flat surfaces, yet many animals can climb highly curved surfaces, like twigs and small branches.
Barnes, W. Jon P.   +7 more
core   +2 more sources

EDNRB‐dependent endothelin signaling reduces proliferation and promotes proneural‐to‐mesenchymal transition in gliomas

open access: yesMolecular Oncology, EarlyView.
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau   +36 more
wiley   +1 more source

Speed Climbing Analysis System Based on Spatial Positioning and Posture Recognition: Design and Effectiveness Assessment

open access: yesApplied Sciences
The human body posture and trajectory are important parameters of the optimal path in speed climbing, and current researchers are focused on them. However, the performance of the newly developed analysis tools for synchronously and accurately analyzing ...
Pingao Huang   +4 more
doaj   +1 more source

Research on the water and land motion performance of an amphibious vehicle

open access: yesXibei Gongye Daxue Xuebao, 2021
The key motions of land and water are analyzed for a designed amphibious carrier robot. On land, based on the characteristics of the multi-joint crawler, the robot has planned two gaits for climbing steps on land.

doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

open access: yesMolecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric   +10 more
wiley   +1 more source

High Speed Stability and Control Characteristics of a 0.17-Scale Model of the McDonnell XF2H-1 Airplane (TED No. NACA DE 318) [PDF]

open access: yes, 1949
High-speed wind-tunnel tests were conducted of two versions of a 0.17-scale model of the McDonnell XF2H-1 airplane to ascertain the high-speed stability and control characteristics and to study means for raising the high-speed buffet limit of the ...
Axelson, John A., Emerson, Horace F.
core   +1 more source

Apparent negative motion of vortex matter due to inhomogeneous pinning [PDF]

open access: yes, 2007
We investigate the transport of vortices in superconductors with inhomgeneous pinning under a driving force. The inhomogeneity of pinning is simplified as strong-weak pinning regions. It is demonstrated that the interactions between the vortices captured
Ding, S.Y.   +7 more
core   +2 more sources

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

open access: yesMolecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova   +14 more
wiley   +1 more source

Electrolytic lesions within central complex neuropils of the cockroach brain affect negotiation of barriers [PDF]

open access: yes, 2010
Animals must negotiate obstacles in their path in order to successfully function within natural environments. These actions require transitions from walking to other behaviors, many of which are more involved than simple reflexes.
Harley, C. M., Ritzmann, R. E.
core   +2 more sources

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