Results 111 to 120 of about 4,184,316 (250)
FEBS Open Bio, EarlyView.Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas +6 more
wiley +1 more source
Ionomycin suppresses cancer cell growth by disrupting mitochondrial transcription
FEBS Open Bio, EarlyView.In this study, we identify a new function for the selective Ca2+ ionophore, ionomycin, as an inhibitor of mitochondrial transcription. Both total and nascent RNA analyses revealed that ionomycin treatment reduces the transcription of mitochondrial genes.
Lishen Wang +10 more
wiley +1 more source
Multi-objective Optimization Analysis of High Speed Gearbox based on Parametric Design
Jixie chuandong, 2016 To improve the static and dynamic characteristics of a high speed gearbox,the main object method of multi-objective optimization is applied in optimization analysis of structures in the high speed gearbox based on parametric design.
Gang Haiming, Liu Zhilei, Ge Shixiang
doaj
Cooperative Bacterial Foraging Algorithm for Global Optimization
, 2009 Bacterial Foraging Optimization (BFO) is a novel optimization algorithm based on the social foraging behavior of E. coli bacteria. However, the original BFO algorithm possesses a poor convergence behavior compared to the other successful nature-inspired ...
Chen HN(陈瀚宁) +5 more
core +1 more source
FEBS Open Bio, EarlyView.Lactoferrin promotes wound healing by activating MAPK, PI3K/Akt, and extracellular matrix pathways, enhancing fibroblast remodeling, proliferation, and re‐epithelialization. These mechanisms highlight its therapeutic potential in inflammation control, tissue repair, and remodeling.
Morgana Lüdtke Azevedo +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty +13 more
wiley +1 more source
In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols
FEBS Open Bio, EarlyView.Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton +6 more
wiley +1 more source
FEBS Open Bio, EarlyView.We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen +5 more
wiley +1 more source
VehiclesGiven the considerable length and weight of freight trains, their operation can be quite challenging. Improper operation may lead to train decoupling and derailment.
Xubin Sun +5 more
doaj +1 more source
SpaceLiner Rocket-Powered High-Speed Passenger Transportation Concept Evolving in FAST20XX [PDF]
, 2010 The revolutionary ultrafast passenger transport SpaceLiner is under investigation at DLR since more than 5 years. The two-stage, fully reusable vehicle is powered by rocket engines.
Foreest, Arnold van, Sippel, Martin
core