Results 91 to 100 of about 1,116,535 (288)

Oocyte Penetration Speed Optimization Based on Intracellular Strain. [PDF]

open access: yesMicromachines (Basel), 2022
Liu Y   +5 more
europepmc   +1 more source

Optimization of patch antennas via multithreaded simulated annealing based design exploration [PDF]

open access: yes, 2017
In this paper, we present a new software framework for the optimization of the design of microstrip patch antennas. The proposed simulation and optimization framework implements a simulated annealing algorithm to perform design space exploration in order
Richie, James, Ababei, Cristinel
core   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

open access: yesMolecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen   +9 more
wiley   +1 more source

Low speed aerofoil optimization

open access: yes, 2022
A topologia de perfis aerodinâmicos tem uma influência significativa no desempenho de aeronaves. Múltiplas metodologias podem ser aplicadas para definir perfis, tais como projeto direto, projeto inverso ou projeto por desempenho. Com o desenvolvimento da tecnologia computacional, tem havido uma tendência contínua para automatizar o projeto de perfis ...
openaire   +1 more source

Molecular cancer prevention: Intercepting disease

open access: yesMolecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco   +2 more
wiley   +1 more source

Optimization procedure for variable speed turbine design

open access: yesEngineering Applications of Computational Fluid Mechanics, 2018
This article outlines a design procedure for variable speed Francis turbines using optimization software. A fully parameterized turbine design procedure is implemented in MATLAB $ ^{\circledR } $ . ANSYS $ ^{\circledR } $ CFX $ ^{\circledR } $ is used to
Erik Tengs   +2 more
doaj   +1 more source

The Optimization of Marine Diesel Engine Rotational Speed Control Process by Fuzzy Logic Control Based on Particle Swarm Optimization Algorithm

open access: yesFuture Internet, 2018
The marine main diesel engine rotational speed automatic control plays a significant role in determining the optimal main diesel engine speed under impacting on navigation environment conditions.
Tien Anh Tran
doaj   +1 more source

Airfoil optimization with efficient gradient calculations [PDF]

open access: yes
The viscous airfoil design analysis code XFOIL was extended to allow optimization using conformal mapping coefficients as design variables. The optimization technique used was the Steepest Descent method applied to a Penalty Function.
Sorensen, Thomas
core   +1 more source

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