Results 151 to 160 of about 3,958,960 (312)
Molecular Oncology, EarlyView.Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur +11 more
wiley +1 more source
, 1918 This is a photograph of the death certificate for John Speed, deceased on 1918-03-31, filed with the Arkansas Department of Health by the Ruebel Funeral Home in Little Rock.Transcribed.
Ruebel Funeral Home (Little Rock, Ark.)
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Stricter regulation boosts exports: the case of Maximum Residue Levels in pesticides [PDF]
, 2014 Constructing an original panel on Maximum Residue Levels (MRLs) in pesticides for 50 countries over 2006-2012, this paper studies the effect of heterogeneity in MRL regulation on bilateral trade.
Foletti, Liliana, Shingal, Anirudh
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Molecular Oncology, EarlyView.Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq +8 more
wiley +1 more source
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
The relationship between speed and income is established in a micro- economic model focusing on the trade-off between travel time and the risk of receiving a penalty for exceeding the speed limit.
Mogens Fosgerau
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Molecular Oncology, EarlyView.We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee +3 more
wiley +1 more source
RESEARCH ON FUZZY CONTROL SIMULATION OF CVT RATIO BASED ON ENGINE SPEED REGULATION CHARACTERISTICS
Jixie qiangdu, 2019 According to the load characteristics and speed regulation characteristics of the engine,the steady-state torque model is established and the optimum power and economy curves of engine are determined. Then the engine target speed is obtained by using the
GUO Wei, JIA GaoXiang, ZHANG Wu, CHEN Ya
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Molecular Oncology, EarlyView.Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou +4 more
wiley +1 more source
Research on Traction Speed Regulation and Braking Device of Pipeline Intelligent Plugging Robot
工程科学与技术ObjectiveWith increasing pipeline mileage and service time, more pipelines are being damaged due to environmental corrosion and human factors. This damage results in interruptions in transport and leakage of oil and gas, which in turn causes economic ...
TANG Yang +3 more
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