Results 181 to 190 of about 135,870 (298)

SOX5 Orchestrates Malignant Evolution via Promoter‐Centric Chromatin Remodeling in MYC‐Driven B‐Cell Lymphoma

Advanced Science, EarlyView.
In MYC‐enforced B‐cell lymphoma, SOX5 occupies promoter‐proximal regulatory regions and is associated with reduced chromatin accessibility at the PCNP locus. PCNP repression promotes proliferative remodeling by limiting apoptosis and cell‐cycle restraint.
Yiyou Mao, Zhenyuan Jia, Xiao‐Qin Mu, Ruilin Wang, Jianli Ma, Qingyuan Zhang, Yuwei Deng   +6 more
wiley   +1 more source

Detecting Uncoded Self-Harm in Veterans' Electronic Health Records Using Positive and Unlabeled Learning: Retrospective Cohort Study. [PDF]

J Med Internet Res
Kumar P, Viszolay AD, Upadhayaya R, Moomtaheen F, Greer DR, Bologa CG, Schneider KA, Davis SE, Matheny ME, van der Goes D, Villarreal G, Zhu Y, Tohen M, Malec SA, Yang JJ, Fielstein EM, Lambert CG.   +16 more
europepmc   +1 more source

Closing the Empirical Loop: Autonomous AI Agents Conduct End‐to‐end Research With Human Participants

Advanced Science, EarlyView.
A multi‐agent AI system autonomously executes the complete scientific workflow, from hypothesis to manuscript, across three psychological studies involving 288 participants. The system designs experiments, collects real world data, develops analysis pipelines, and writes manuscripts with theoretical rigor comparable to experienced researchers.
Gabrielle Wehr, Reuben Rideaux, Amaya J. Fox, David R. Lightfoot, Jason Tangen, Jason B. Mattingley, Shane E. Ehrhardt   +6 more
wiley   +1 more source

Preoperative circulating tumor DNA detection and occult lymph node metastases in clinical stage I lung cancer: The lung DETECT study. [PDF]

JTCVS Open
Coyne Z, Feng J, Khan S, Yasufuku K, Donahoe L, Pierre A, Keshavjee S, Cypel M, Yeung J, de Perrot M, Safieddine N, Ahmadi N, Simone C, Gazala S, Ko M, Parente D, Cheung V, Salvarrey A, Le LW, Rabey MR, Law JH, Leighl NB, Waddell TK.   +22 more
europepmc   +1 more source

Arabisc: Context-Sensitive Neural Spelling Checker

Proceedings of the 6th Workshop on Natural Language Processing Techniques for Educational Applications, 2020
Moslem, Yasmin, Haque, Rejwanul, Way, Andy   +2 more
openaire   +2 more sources

Transposable Element–Driven PIEZO Mutation Enhances Locust Flight in Plateau Hypoxia

Advanced Science, EarlyView.
Why transposable elements (TEs) persisted or expanded in genomes remains a mystery. Using integrated analysis of TE macro‐ and microevolution in locusts, our results showed that thousands of TE insertions promoted widespread adaptive variation. Subfamilies of candidate adaptive TEs amplified and reshaped species‐level genomic architecture.
Xuanzhao Li, Ying Liu, Longsheng Xing, Xianliang Huang, Yingming Sun, Lei Yue, Yuze Zhang, Huilong Du, Bing Chen   +8 more
wiley   +1 more source

Dataset creation and benchmarking for Kashmiri news snippet classification using fine-tuned transformer and LLM models in a low resource setting. [PDF]

Sci Rep
Deyar DU, Ramani A, Gupta D, Nair PC, Venugopalan M.   +4 more
europepmc   +1 more source

Igala Language Spell Checker

Current Journal of Applied Science and Technology, 2017
Sani Ayegba, Musa Ugbedeojo, Benson-Iyare Chinezie, Onoja Abu   +3 more
openaire   +1 more source

Pasta, a Versatile Transcriptomic Clock, Maps the Chemical and Genetic Determinants of Aging and Rejuvenation

Advanced Science, EarlyView.
Pasta is a transcriptomic aging clock built on an age‐shift learning framework and trained on 17 000 samples across 21 datasets. It accurately predicts relative biological age across tissues, platforms, and species, captures stemness‐to‐senescence transitions, and identifies age‐modulatory perturbations.
Jérôme Salignon, Maria Tsiokou, Patricia Marqués, Enriqueta Rodríguez‐Diaz, Hazel Ang, Federico Pietrocola, Christian G. Riedel   +6 more
wiley   +1 more source

Equivariant spherical CNNs for accurate fiber orientation distribution estimation in neonatal diffusion MRI with reduced acquisition time. [PDF]

Front Neurosci
Snoussi H, Karimi D.
europepmc   +1 more source