Results 101 to 110 of about 726,910 (390)

Sperm protein 17 is expressed in the sperm fibrous sheath [PDF]

open access: yesJournal of Translational Medicine, 2009
Sperm protein 17 (Sp17) is a highly conserved mammalian protein characterized in rabbit, mouse, monkey, baboon, macaque, human testis and spermatozoa. mRNA encoding Sp17 has been detected in a range of murine and human somatic tissues. It was also recognized in two myeloma cell lines and in neoplastic cells from patients with multiple myeloma and ...
Francesco Costa   +12 more
openaire   +4 more sources

Integration of Bioengineered Tools in Assisted Reproductive Technologies

open access: yesAdvanced Healthcare Materials, EarlyView.
A conceptual illustration depicting the collaboration between a medical professional (right) and a scientist (left). Their connection highlights the integration of scientific research and clinical practice. This representation underscores the role of emerging technologies in bridging fundamental research with applied reproductive healthcare.
Aslı Ak   +3 more
wiley   +1 more source

KIF2A Upregulates PI3K/AKT Signaling through Polo-like Kinase 1 (PLK1) to Affect the Proliferation and Apoptosis Levels of Eriocheir sinensis Spermatogenic Cells

open access: yesBiology
E. sinensis is an animal model for studying the reproduction and development of crustaceans. In this study, we knocked down the Es-Kif2a gene by injecting dsRNA into E.
Yan-Shuang Zhao   +3 more
doaj   +1 more source

Relative safety of various spermatogenic stem cell purification methods for application in spermatogenic stem cell transplantation

open access: yesStem Cell Research & Therapy, 2019
Background Spermatogonial stem cell (SSC) transplantation technology as a promising option for male fertility preservation has received increasing attention, along with efficient SSC purification technology as a necessary technical support; however, the ...
Jia Tian   +8 more
doaj   +1 more source

Measuring Sperm DNA Fragmentation and Clinical Outcomes of Medically Assisted Reproduction: A Systematic Review and Meta-Analysis

open access: yesPLoS ONE, 2016
Sperm DNA fragmentation has been associated with reduced fertilization rates, embryo quality, pregnancy rates and increased miscarriage rates. Various methods exist to test sperm DNA fragmentation such as the sperm chromatin structure assay (SCSA), the ...
M. Cissen   +8 more
semanticscholar   +1 more source

From Mechanoelectric Conversion to Tissue Regeneration: Translational Progress in Piezoelectric Materials

open access: yesAdvanced Materials, EarlyView.
This review highlights recent progress in piezoelectric materials for regenerative medicine, emphasizing their ability to convert mechanical stimuli into bioelectric signals that promote tissue repair. Key discussions cover the intrinsic piezoelectric properties of biological tissues, co‐stimulation cellular mechanisms for tissue regeneration, and ...
Xinyu Wang   +3 more
wiley   +1 more source

Leveraging Design of Experiments to Unravel the Amplification Mechanism of Single‐Molecule Wide‐Field Biosensors

open access: yesAdvanced Materials Interfaces, EarlyView.
Detecting single molecules on large interfaces is challenging due to minimal perturbations on the sensing surface. Some biological systems achieve this feat using amplification mechanisms, but their molecular foundations remain unclear. To investigate, a Design of Experiments (DoE) approach examines how pH and ionic strength in conditioning solutions ...
Michele Catacchio   +9 more
wiley   +1 more source

Fertility outcome of patients with testicular tumor: before and after treatment

open access: yesAsian Journal of Andrology, 2014
Testicular cancer (TC) is the most curable type of cancer, with a survival rate of more than 95%. Oncologists are faced with the challenge that gonadotoxic cancer treatments can compromise future fertility, either temporarily or permanently.
Ping Ping   +4 more
doaj   +1 more source

Abnormal Human Sperm Parameters Contribute to Sperm DNA Fragmentation in Men with Varicocele [PDF]

open access: yesThe World Journal of Men's Health, 2018
Purpose: This study was performed to evaluate and compare threshold sperm parameters and sperm DNA fragmentation index (DFI), and further analyzed whether sperm DFI could be predicted from sperm parameters in men with varicocele.
Yong-Seog Park   +5 more
doaj   +1 more source

Etiologies of sperm oxidative stress

open access: yesInternational Journal of Reproductive BioMedicine, 2016
Sperm is particularly susceptible to reactive oxygen species (ROS) during critical phases of spermiogenesis. However, the level of seminal ROS is restricted by seminal antioxidants which have beneficial effects on sperm parameters and developmental ...
P. Sabeti   +4 more
semanticscholar   +1 more source

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