Results 111 to 120 of about 487,985 (362)
Epilepsia Open, EarlyView., 2022 Abstract Rodent models of epilepsy remain the cornerstone of research into the mechanisms underlying genetic epilepsy. Reproducibility of experiments using these rodent models, occurring across a diversity of laboratories and commercial vendors, remains an issue impacting the cost‐effectiveness and scientific rigor of the studies performed.
Massimo Mantegazza +7 more
wiley +1 more source
Cryopreservation of Pike Perch Sperm in Hatchery Conditions [PDF]
, 2008 Experiments were carried out on pike perch (Sander lucioperca L.) to find a method for stripping sperm without contamination by urine, to determine sperm concentration, and to fertilize large batches of eggs with cryopreserved sperm.
Bokor, Zoltán +3 more
core
Evidence of the presence of calcium/calmodulin-dependent protein kinase IV in human sperm and its involvement in motility regulation [PDF]
, 2005 The mechanisms involved in the regulation of mammalian sperm motility are not well understood. Calcium ions (Ca(2+)) have been suggested to play a key role in the maintenance of motility; nevertheless, how Ca(2+) modulates this process has not yet been ...
Buffone, Mariano Gabriel +6 more
core +1 more source
The dynamics of sperm cooperation in a competitive environment [PDF]
arXiv, 2014 Sperm cooperation has evolved in a variety of taxa and is often considered a response to sperm competition, yet the benefit of this form of collective movement remains unclear. Here we use fine-scale imaging and a minimal mathematical model to study sperm aggregation in the rodent genus $Peromyscus$.
arxiv
Advanced Science, EarlyView.Prenatal dexamethasone exposure (PDE) can induce dysfunction in adrenal steroid synthesis in adult male offspring. This study demonstrate that the mechanism is associated with the upregulation of fetal adrenal cholesterol 27 hydroxylase (CYP27A1)promoter region histone 3 lysine 27 acetylation (H3K27ac) levels and expression mediated by PDE through the ...
Jiangang Cao +7 more
wiley +1 more source
Sex‐dependent effects of parental age on offspring fitness in a cooperatively breeding bird
Evolution Letters, Volume 6, Issue 6, Page 438-449, December 2022., 2022 Abstract Parental age can have considerable effects on offspring phenotypes and health. However, intergenerational effects may also have longer term effects on offspring fitness. Few studies have investigated parental age effects on offspring fitness in natural populations while also testing for sex‐ and environment‐specific effects.
Alexandra M. Sparks +5 more
wiley +1 more source
A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities [PDF]
, 2017 To fertilize an oocyte, sperm must first undergo capacitation in which the sperm plasma membrane becomes hyperpolarized via activation of potassium (K(+)) channels and resultant K(+) efflux.
Butler, Alice +8 more
core +2 more sources
Improving Human Sperm Head Morphology Classification with Unsupervised Anatomical Feature Distillation [PDF]
arXiv, 2022 With rising male infertility, sperm head morphology classification becomes critical for accurate and timely clinical diagnosis. Recent deep learning (DL) morphology analysis methods achieve promising benchmark results, but leave performance and robustness on the table by relying on limited and possibly noisy class labels.
arxiv
DAPK3 is Essential for DBP‐Induced Autophagy of Mouse Leydig Cells
Advanced Science, EarlyView.This study has confirmed that death‐associated protein kinase 3 (DAPK3) is essential for dibutyl phthalate (DBP)‐induced autophagy of mouse Leydig cells, and is regulated by both transcription factor specific protein 2 (Sp2) and parkin RBR E3 ubiquitin‐protein ligase (PRKN), and melatonin can alleviate DBP‐induced autophagy of the cells.
Si Yang +4 more
wiley +1 more source
, 2022 Animal Models and Experimental Medicine, Volume 5, Issue 6, Page 587-588, December 2022.
wiley +1 more source