Results 131 to 140 of about 487,985 (362)
Stem Cell Reports, 2014 Generation of functional spermatids from azoospermia patients is of unusual significance in the treatment of male infertility. Here, we report an efficient approach to obtain human functional spermatids from cryptorchid patients.
Shi Yang +10 more
doaj +1 more source
eLife, 2013 Human sperm cells rely on an unusual type of potassium ion channel.
openaire +5 more sources
Strictures of the female reproductive tract impose fierce competition to select for highly motile sperm [PDF]
arXiv, 2018 Investigating sperm locomotion in the presence of an external fluid flow and geometries simulating the female reproductive tract can lead to a better understanding of sperm motion during the fertilization process. In this study, using a microfluidic device featuring a stricture that simulates the biophysical properties of narrow junctions inside the ...
arxiv
Aggregate, EarlyView.Pathogen‐derived extracellular vesicle detection: theoretical insights and advanced methodologies: This review explores the theoretical foundations and practical applications of pEV detection, emphasizing the challenges and innovative strategies involving novel aggregate materials and machine learning for enhanced diagnostic accuracy.
Lihan Lai +6 more
wiley +1 more source
Mutations in OOEP and NLRP5 identified in infertile patients with early embryonic arrest
Human Mutation, Volume 43, Issue 12, Page 1909-1920, December 2022., 2022 Abstract The subcortical maternal complex (SCMC), composed of several maternal‐effect genes, is vital for the development of oocytes and early embryos. Variants of SCMC‐encoding genes (NLRP2, NLRP5, TLE6, PADI6, and KHDC3L, but not OOEP and ZBED3) are associated with human oocyte maturation dysfunction, fertilization failure, and early embryonic arrest.
Xiaomei Tong +6 more
wiley +1 more source
A novel stepwise micro-TESE approach in non obstructive azoospermia [PDF]
, 2016 Background: The purpose of the study was to investigate whether micro-TESE can improve sperm retrieval rate (SRR) compared to conventional single TESE biopsy on the same testicle or to contralateral multiple TESE, by employing a novel stepwise micro ...
Casciani, V +9 more
core +2 more sources
Competition among eggs shifts to cooperation along a sperm supply gradient in an external fertilizer [PDF]
arXiv, 2015 Competition among gametes for fertilization imposes strong selection. For external fertilizers, this selective pressure extends to eggs for which spawning conditions can range from sperm limitation (competition among eggs) to sexual conflict (overabundance of competing sperm toxic to eggs).
arxiv
Human Mutation, Volume 43, Issue 12, Page 2205-2221, December 2022., 2022 Mutation frequency heat map of spontaneous PTPN11 variants show spatial clustering in the testis due to germline selection explaining the high birth incidence of Noonan syndrome. Some somatic PTPN11 cancer mutations are similarly clustered in testis. Abstract Some spontaneous germline gain‐of‐function mutations promote spermatogonial stem cell clonal ...
Jordan Eboreime +6 more
wiley +1 more source
Characteristics and Possible Role of Bovine Sperm Head-to-Head Agglutination
Cells, 2020 Although sperm head-to-head agglutination has been reported in many mammalian species, the biological significance of this unique sperm–sperm interaction remains largely unknown.
Kohei Umezu +6 more
doaj +1 more source
Larger testes are associated with a higher level of polyandry, but a smaller ejaculate volume, across bushcricket species (Tettigoniidae) [PDF]
, 2010 While early models of ejaculate allocation predicted that both relative testes and ejaculate size should increase with sperm competition intensity across species, recent models predict that ejaculate size may actually decrease as testes size and sperm ...
Darren J. Parker +3 more
core +3 more sources