Results 141 to 150 of about 740,952 (392)

DNA demethylation by ROS1a in rice vegetative cells promotes methylation in sperm. [PDF]

, 2019
Epigenetic reprogramming is required for proper regulation of gene expression in eukaryotic organisms. In Arabidopsis, active DNA demethylation is crucial for seed viability, pollen function, and successful reproduction. The DEMETER (DME) DNA glycosylase
Fischer, Robert L, Kim, M Yvonne, Kinoshita, Tetsu, Okamoto, Takashi, Ono, Akemi, Scholten, Stefan, Zilberman, Daniel   +6 more
core   +2 more sources

TSHR‐Targeting Nucleic Acid Aptamer Treats Graves' Ophthalmopathy via Novel Allosteric Inhibition

Advanced Science, EarlyView.
This study presents YC3, a novel inhibitory TSHR‐targeting aptamer, as a promising therapeutic for Graves' ophthalmopathy (GO). YC3 suppresses pathological phenotypes in human orbital fibroblasts and improves outcomes in GO mice by binding to a previously unidentified allosteric site on TSHR, demonstrating the potential of aptamers in advancing ...
Yanchen Zhang, Ende Wu, Weibin Liu, Ling Zeng, Neng Ling, Hongmei Wang, Zhixing Li, Shuang Yao, Tonghe Pan, Xuanwen Li, Yate Huang, Xiaojing Li, Yunhai Tu, Wentao Yan, Jianzhang Wu, Mao Ye, Wencan Wu   +16 more
wiley   +1 more source

The Effect of X-Rays on Cytological Traits of Tuta absoluta (Lepidoptera: Gelechiidae) [PDF]

, 2016
The tomato leafminer, Tuta absoluta (Meyrick) (Lepidoptera: Gelechiidae) is one of the most important pests of tomato. With the purpose of developing environmentally friendly control tactics such as the inherited sterility (IS) technique against this ...
Cagnotti, Cynthia Lorena, Carabajal Paladino, Leonela Zusel, Ferrari, María Edith, Lauría, Juan P., López, Silvia Noelí, Síchová, Jindra   +5 more
core   +1 more source

Stage‐Resolved Phosphoproteomic Landscape of Mouse Spermiogenesis Reveals Key Kinase Signaling in Sperm Morphogenesis

Advanced Science, EarlyView.
The quantitative proteomic and phosphoproteomic profiling reveals dynamic phosphorylation regulation of sperm morphogenesis. Kinase‐substrate phosphorylation network and phosphorylation module analysis, followed by in vivo knockdown and knockout analysis, identify TTBK2 and CSNK1G1 as key regulators of morphogenesis, including head, flagellar, and ...
Tianyu Zhu, Yan Zhu, Xinyi Jiang, Xiangzheng Zhang, Bing Wang, Yu Chen, Yichen Zhao, Yulian Wang, Qi Zhou, Zhongyan Han, Yaling Qi, Mengjiao Luo, Haixia Tu, Bingjie Hao, Mengmeng Gao, Jie Ren, Xin Zhou, Xingyu Zhang, Xu Chen, Haojie Li, Qian Huang, Chenghao Situ, Yueshuai Guo, Hui Zhu, Yan Li, Xuejiang Guo   +25 more
wiley   +1 more source

Does abnormal weight affect sperm quality? A case-control study based on bioelectrical impedance analysis

Frontiers in Nutrition
IntroductionWeight gain can lead to metabolic, circulatory, and systemic changes. Obesity has been confirmed to induce various physical and mental illnesses.
Huang Liu, Xiaoxia Wang, Li Li, Zhiyong Zhu, Hai Lin, Yu Zhou, Houbin Zheng   +6 more
doaj   +1 more source

In-vitro application of pentoxifylline preserved ultrastructure of spermatozoa after vitrification in asthenozoospermic patients [PDF]

, 2017
PURPOSE: To evaluate the effect of in vitro application of pentoxifylline (PX) on sperm parameters and ultrastructure after vitrification in asthenozoospermic patients. MATERIALS AND METHODS: A total of 30 asthenozoospermic semen samples (aged 25-45
Khalili, Ma, Mangoli, E, Miglietta, S, Nabi, A, Nottola, Sa, Taheri, F., Talebi, Ar, Yari, N   +7 more
core  

Sperm mobility: mechanisms of fertilizing efficiency, genetic variation and phenotypic relationship with male status in the domestic fowl, Gallus gallus domesticus [PDF]

, 2002
When females are sexually promiscuous, sexual selection continues after insemination through sperm competition and cryptic female choice, and male traits conveying an advantage in competitive fertilization are selected for. Although individual male and
Allen J Feltmann, David P Froman, Hector Castillo-Juarez, Pizzari T., Sullivan M. S., Tim R Birkhead, Tommaso Pizzari   +6 more
core   +2 more sources

Banke sperme [PDF]

, 2015
Banka sperme (ili kriobanka) je način/mogućnost pohrane sperme čovjeka. Spermu potom koriste žene koje žele postići trudnoću i materinstvo. Dva su glavna razloga zašto se muškarci odluče na pohranu (donaciju) sperme: 1) da bi osigurali reproduktivnu sposobnost kada su suočeni s bolešću koja bi mogla biti smrtonosna ili čije bi liječenje moglo ...
openaire   +1 more source

Optimal Chirality Enhances Long‐Range Fluctuation‐Induced Interactions in Active Fluids

Advanced Science, EarlyView.
Chiral active particles move along curved trajectories arising from the interplay of propulsion and self‐rotation. How chirality influences fluctuation‐induced forces in active matter systems remains unclear. It is shown that particle shape dictates this effect: chirality suppresses forces for circular particles but can enhance them for elongated ones,
Hashem Fatemi, Hamidreza Khalilian, Jalal Sarabadani, Reza Shaebani   +3 more
wiley   +1 more source

Ex Vivo Spatiotemporal Characterization of Spermatogenesis in Mouse Testicular Organoids

Advanced Science, EarlyView.
To date, in vitro spermatogenesis remains a challenge in reproductive medicine. In this study, Sun et al. developed a promising in vitro strategy to generate testicular organoids that enable germ cells from newborn mice to enter meiosis, complete chromosome recombination and synapsis, and develop into haploid spermatids.
Jiachen Sun, Lifa Zhu, Yutong Li, Jinyan Tang, Tao Zhang, Hengjia Zhang, Wanchu Wang, Lufan Li, Shuhui Bian, Xin Wu   +9 more
wiley   +1 more source