Results 161 to 170 of about 192,203 (268)

Routine MDM2 FISH Testing and Preoperative Biopsy Reduces Recurrence Rate of Atypical Lipomatous Tumours

Journal of Surgical Oncology, EarlyView.
ABSTRACT Background Although MDM2 FISH test has been increasingly used to differentiate ALT and benign lipomatous tumours, its impact on clinical outcome remains underexplored. This study investigated whether routine MDM2 FISH testing on preoperative biopsy is associated with a reduction in the recurrence risk of ALT.
Samuel O. H. Ching, Anderson S. M. Leung, Raymond C. H. Yau, Albert Y. L. Lam, Tony W. H. Shek, Maximus C. F. Yeung   +5 more
wiley   +1 more source

Retrospective cohort study of intracytoplasmic sperm injection outcomes using testicular <i>vs</i>. ejaculated sperm among patients with non-obstructive azoospermia or cryptozoospermia. [PDF]

Transl Androl Urol
Durbin CG, Weidenbaum E, Alcide P, Rothschild C, Werner M, Blakemore JK, McCaffrey C, Najari BB.   +7 more
europepmc   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source

Effects of Epimedium supplementation on post-thaw spermatological and oxidative stress parameters in bull semen. [PDF]

Trop Anim Health Prod
Gökdemir T, Önder NT, Kiliç MC, Şahi̇n O, Başer L, Öztürkler Y, Yıldız S.   +6 more
europepmc   +1 more source

Sickle Cell Disease: Historical Overview and Current Therapies

Prenatal Diagnosis, EarlyView.
ABSTRACT Sickle cell disease (SCD) affects millions worldwide, yet the limited treatment options currently available do not always adequately control the disease and carry significant side effects. At present, the only curative treatment is hematopoietic stem cell (HSC) transplantation, a procedure that carries considerable challenges and numerous ...
Oluwaseun O. Babatunde, Madeleine G. Bibby, Anthony Atala, Graça Almeida‐Porada, Christopher D. Porada   +4 more
wiley   +1 more source

Heat exposure during susceptible windows of spermatogenesis and sperm epigenetic age. [PDF]

Hum Reprod
Nobles C, Canty TP, Mendola P, Russo LM, Rabeya K, Schliep KC, Shaaban M, Singh A, Ring AM, Hemmert R, Perkins NJ, Oluwayiose OA, Peterson CM, Nowak K, Pilsner JR.   +14 more
europepmc   +1 more source

Structural Variation Sequencing of 26 Amniotic Fluid Samples With Partial Gene Duplications and Postnatal Follow‐Up of the Fetuses

Prenatal Diagnosis, EarlyView.
ABSTRACT Objectives Partial gene duplications (PGDups) are a significant contributor to genetic disease. The precise genomic location and structure of PGDups are often unresolved using conventional methods, so prenatal diagnosis for PGDups is challenging, especially without ultrasound abnormalities.
Shengfang Qin, Xueyan Wang, Mengjia Yan, Yuxia He, Zhuo Zhang, Yan Yin, Jin Wang, Beibei Guo, Jing Wang, Na Xi, Zhaokai Li   +10 more
wiley   +1 more source

Dietary restriction induces persistent multigenerational phenotypic effects in Phytoseiulus persimilis

Pest Management Science, EarlyView.
The study shows ancestral dietary restriction in Phytoseiulus persimilis produces persistent, sex‐specific, multi‐generational effects on survival and body size, with stronger maternal than paternal lineage influences despite nutritional recovery. Abstract BACKGROUND Transgenerational phenotypic plasticity (TGP) allows environmental effects to persist ...
Xia Chen, Keshi Zhang, Xiao Han, Yun Xu, Zhi‐Qiang Zhang   +4 more
wiley   +1 more source

Dose‐dependent efficacy of a novel dsRNA‐based solution containing vadescana for Varroa destructor control

Pest Management Science, EarlyView.
Vadescana is a novel dsRNA‐based product that targets Varroa fecundity. Vadescana applied at 4 g/brood box in one application was most effective at reducing Varroa populations for up to 18 weeks. Abstract BACKGROUND A novel dsRNA‐based product, containing a molecule called vadescana, interferes with Varroa destructor (Anderson and Trueman) fecundity ...
Briana E Price, Ryan Kuesel, Taylor Reams, Brian Manley, James Masucci, Brandon K Hopkins   +5 more
wiley   +1 more source

Garment fit, scrotal thermoregulation, and male fertility outcomes: a narrative review. [PDF]

Transl Androl Urol
Zleczewski M, Clay N, Lambert J, Stroie F.   +3 more
europepmc   +1 more source