Results 191 to 200 of about 487,985 (362)

Combined Analysis of the Transcriptome, Proteome and Metabolome in Human Cryopreserved Sperm

open access: yesThe World Journal of Men's Health
Purpose: This study aimed to identify the altered pathways and genes associated with freezing damage in human sperm during cryopreservation by multiomics analysis.
Longlong Fu   +8 more
doaj   +1 more source

The Heterotaxy Gene CCDC11 Is Important for Cytokinesis via RhoA Regulation

open access: yesCytoskeleton, EarlyView.
ABSTRACT Mutations in CCDC11 (cfap53) have been identified in multiple patients with heterotaxy (Htx), a disorder of left–right (LR) patterning of the internal organs. In Xenopus, depletion of Ccdc11 causes defects in LR patterning, recapitulating the patient phenotype. Upon Ccdc11 depletion, monociliated cells of the Left–Right Organizer (LRO) exhibit
Saurabh S. Kulkarni   +9 more
wiley   +1 more source

Banke sperme

open access: yes, 2015
Banka sperme (ili kriobanka) je način/mogućnost pohrane sperme čovjeka. Spermu potom koriste žene koje žele postići trudnoću i materinstvo. Dva su glavna razloga zašto se muškarci odluče na pohranu (donaciju) sperme: 1) da bi osigurali reproduktivnu sposobnost kada su suočeni s bolešću koja bi mogla biti smrtonosna ili čije bi liječenje moglo ...
openaire   +1 more source

TRiC Is a Structural Component of Mammalian Sperm Axonemes

open access: yesCytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown   +3 more
wiley   +1 more source

Effects of Cholesterol on the Breast Cancer Resistance Protein: Studies through the Synthesis and Biological Evaluation of Chemical Tools

open access: yesChemMedChem, EarlyView.
This study explores the role of cholesterol in the regulation of the efflux pump ABCG2. Substrates and inhibitors of ABCG2, cholesterol linked to fluorescents probes were synthesized and tested to investigate the influence of cholesterol on ABCG2 inhibition and to track cholesterol trafficking on cells.
Ingrid Fatima Zattoni   +6 more
wiley   +1 more source

Determination of crucial epitopes in the sperm protein calsperin employing synthetic peptides and monoclonal antibodies

open access: yesJournal of Peptide Science, Volume 29, Issue 2, February 2023., 2023
An epitope located at the C‐terminal end of calsperin corresponding to amino acids 228WEKHFLDAS237 was identified by using two monoclonal antibodies and resin‐bound calsperin peptides. Three hot spot amino acids were essential for antibody binding.
Ann Christina Bergmann   +2 more
wiley   +1 more source

Home - About - Disclaimer - Privacy