Results 211 to 220 of about 487,985 (362)

Three cases of sperm immobility for intracytoplasmic sperm injection using testicular sperm

open access: yesIJU Case Reports
Introduction Sperm immobility is a condition in which sperm are viable but not motile. We reported three patients with sperm immobility, who underwent testicular sperm extraction‐intracytoplasmic sperm injection.
Noboru Mimura   +5 more
doaj   +1 more source

Automated Sperm Morphology Analysis Based on Instance-Aware Part Segmentation [PDF]

open access: yesarXiv
Traditional sperm morphology analysis is based on tedious manual annotation. Automated morphology analysis of a high number of sperm requires accurate segmentation of each sperm part and quantitative morphology evaluation. State-of-the-art instance-aware part segmentation networks follow a "detect-then-segment" paradigm.
arxiv  

Severity of effect considerations regarding the use of mutation as a toxicological endpoint for risk assessment: A report from the 8th International Workshop on Genotoxicity Testing (IWGT)

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
Abstract Exposure levels without appreciable human health risk may be determined by dividing a point of departure on a dose–response curve (e.g., benchmark dose) by a composite adjustment factor (AF). An “effect severity” AF (ESAF) is employed in some regulatory contexts.
Barbara L. Parsons   +17 more
wiley   +1 more source

Benchmark Response (BMR) Values for In Vivo Mutagenicity Endpoints

open access: yesEnvironmental and Molecular Mutagenesis, EarlyView.
ABSTRACT The benchmark dose (BMD) approach constitutes the most effective and pragmatic strategy for the derivation of a point of departure (PoD) for comparative potency analysis, risk assessment, and regulatory decision‐making. There is considerable controversy regarding the most appropriate benchmark response (BMR) for genotoxicity endpoints.
Paul A. White   +8 more
wiley   +1 more source

Stopping the Sperm [PDF]

open access: yesBMJ, 1964
M. Matsukura   +3 more
openaire   +3 more sources

Synthetic Biology‐Based Engineering Cells for Drug Delivery

open access: yesExploration, EarlyView.
Synthetic biology‐based therapeutic cells for drug delivery: Engineered cells effectively transport and release drugs through their intelligence and controllability, such as feedback pathways and external stimuli (e.g., light and ultrasound). The integration of nanotechnology, including nanoparticles, biofilms, and artificial cells, enhances ...
Wenzhe Yi   +4 more
wiley   +1 more source

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