Results 61 to 70 of about 754,638 (394)

Comparison of outcomes between pulsatile gonadotropin releasing hormone and combined gonadotropin therapy of spermatogenesis in patients with congenital hypogonadotropic hypogonadism

Reproductive Biology and Endocrinology
Background To evaluate whether there was a difference in outcome between pulsatile gonadotropin releasing hormone (GnRH) therapy and human chorionic gonadotropin/human menopausal gonadotropin (hCG/HMG) therapy for induction of spermatogenesis in post ...
Yi Zheng, Heng-Zhou Bai, Gui-Cheng Zhao, Kun Tian, Jun-Tao Yue, Ding-Ming Li, Xiao-Hui Jiang   +6 more
doaj   +1 more source

PIWIs Regulate Spermatogonia Self-Renewal and Differentiation by Wnt/β-Catenin Signaling Pathway in Eriocheir sinensis

Biology
The roles of PIWI in mammalian spermatogenesis have been well-studied but are largely unknown in invertebrates such as the Chinese mitten crab (Eriocheir sinensis), which produces non-flagellar sperm.
Bang-Hong Wei, Zhan Zhao, Hong-Yu Qi, Zhen-Fang Li, Wan-Xi Yang, Shuang-Li Hao   +5 more
doaj   +1 more source

A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure

HGG Advances, 2023
Summary: Quantitative and qualitative spermatogenic impairments are major causes of men’s infertility. Although in vitro fertilization (IVF) is effective, some couples persistently fail to conceive.
Moran Gershoni, Tslil Braun, Ron Hauser, Shimi Barda, Ofer Lehavi, Mira Malcov, Tsvia Frumkin, Yael Kalma, Shmuel Pietrokovski, Eli Arama, Sandra E. Kleiman   +10 more
doaj   +1 more source

Sperm Viability Matters in Insect Sperm Competition [PDF]

Current Biology, 2005
Experimental studies in insects have shown how sperm competition can be a potent selective force acting on an array of male reproductive traits . However, the role of sperm quality in determining paternity in insects has been neglected, despite the fact that sperm quality has been shown to influence the outcome of sperm competition in vertebrates .
Garcı́a-González, Francisco, Simmons, Leigh W.   +1 more
openaire   +2 more sources

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Egg donors’ attitudes toward identifiability, offspring information, and genetic testing

Reproductive Biology and Endocrinology
Background Research on egg donors’ perspectives regarding identifiability, donor-conceived offspring, and genetic testing remains limited, as most studies have focused on sperm donors.
Emilie Lassen, Josephine G. Lemmen, Guido Pennings, Anne-Bine Skytte   +3 more
doaj   +1 more source

Human sperm displays rapid responses to diet

PLoS Biology, 2019
The global rise in obesity and steady decline in sperm quality are two alarming trends that have emerged during recent decades. In parallel, evidence from model organisms shows that paternal diet can affect offspring metabolic health in a process ...
D. Nätt, U. Kugelberg, Eduard Casas, E. Nedstrand, Stefan Zalavary, P. Henriksson, Carola Nijm, Julia Jäderquist, Johanna Sandborg, E. Flinke, Rashmi Ramesh, Lovisa Örkenby, Filip Appelkvist, Thomas Lingg, N. Guzzi, C. Bellodi, M. Löf, T. Vavouri, Anita Öst   +18 more
semanticscholar   +1 more source

Multi‐omics and low‐input proteomics profiling reveals dynamic regulation driving pluripotency initiation in early mouse embryos

FEBS Open Bio, EarlyView.
Mouse pre‐implantation development involves a transition from totipotency to pluripotency. Integrating transcriptomics, epigenetic profiling, low‐input proteomics and functional assays, we show that eight‐cell embryos retain residual totipotency features, whereas cytoskeletal remodeling regulated by the ubiquitin‐proteasome system drives progression ...
Wanqiong Li, Xi Xiao, Lingbin Qi, Chanyi Li, Sirui Song, Jiaying Qin, Zhigang Xue, Jinfeng Xue, Huaifang Li   +8 more
wiley   +1 more source

A genetic variant of the sperm-specific SLO3 K+ channel has altered pH and Ca2+ sensitivities [PDF]

, 2017
To fertilize an oocyte, sperm must first undergo capacitation in which the sperm plasma membrane becomes hyperpolarized via activation of potassium (K(+)) channels and resultant K(+) efflux.
Butler, Alice, Dzikunu, Victor, Ferreira, Juan J, Geng, Yanyan, Lybaert, Pascale, Magleby, Karl L, Salkoff, Lawrence, Santi, Celia M, Yuan, Peng   +8 more
core   +2 more sources

Tight junction between endothelial cells: the interaction between nanoparticles and blood vessels

Beilstein Journal of Nanotechnology, 2016
Since nanoparticles are now widely applied as food additives, in cosmetics and other industries, especially in medical therapy and diagnosis, we ask here whether nanoparticles can cause several adverse effects to human health.
Yue Zhang, Wan-Xi Yang
doaj   +1 more source