Results 51 to 60 of about 489,854 (362)

Post-Meiotic Intra-Testicular Sperm Senescence in a Wild Vertebrate

open access: yes, 2012
There is growing interest in sperm senescence, both in its underlying mechanisms and evolutionary consequences, because it can impact the evolution of numerous life history traits. Previous studies have documented various types of sperm senescence, but
Richard H. Wagner   +16 more
core   +1 more source

Cryopreservation of single-sperm from semen and testicular samples: a 5-year monocentric experience in hundreds of patients

open access: yesReproductive Biology and Endocrinology
For patients with severe oligozoospermia, cryopreservation of single human spermatozoa highlights its advantages. Previous research has focused on the development of micro-drop single sperm freezing methods with non-biological carriers over the past 20 ...
Shasha Liu   +5 more
doaj   +1 more source

Molecular Basis of Human Sperm Capacitation

open access: yesFront. Cell Dev. Biol., 2018
In the early 1950s, Austin and Chang independently described the changes that are required for the sperm to fertilize oocytes in vivo. These changes were originally grouped under name of “capacitation” and were the first step in the development of in ...
L. C. P. Puga Molina   +5 more
semanticscholar   +1 more source

The sperm’s tale [PDF]

open access: yesInvestigative Genetics, 2014
Copenhagen is as flat as the proverbial pan-cake. A good way to appreciate this is to visit the Rundetaarn, a 35 m tower whose summit is reached by a spiral ramp designed in the 17th century to accommodate a horse and cart carrying books to its elevated library, and in more recent times inviting the competitive attention of puffing middle-aged blokes ...
openaire   +3 more sources

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

open access: yesFEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer   +7 more
wiley   +1 more source

Comparison of outcomes between pulsatile gonadotropin releasing hormone and combined gonadotropin therapy of spermatogenesis in patients with congenital hypogonadotropic hypogonadism

open access: yesReproductive Biology and Endocrinology
Background To evaluate whether there was a difference in outcome between pulsatile gonadotropin releasing hormone (GnRH) therapy and human chorionic gonadotropin/human menopausal gonadotropin (hCG/HMG) therapy for induction of spermatogenesis in post ...
Yi Zheng   +6 more
doaj   +1 more source

Semen parameters are seriously affected in acephalic spermatozoa syndrome

open access: yesBasic and Clinical Andrology, 2022
Résumé Contexte Des études antérieures ont rapporté que certains patients qui avaient des spermatozoïdes sans tête présentaient une mauvaise qualité du sperme, mais il n’y a eu aucune analyse systématique publiée sur la qualité du sperme chez les ...
Li-juan Ying   +7 more
doaj   +1 more source

Chromatin States in Mouse Sperm Correlate with Embryonic and Adult Regulatory Landscapes

open access: yesCell Reports, 2017
SUMMARY The mammalian sperm genome is thought to lack substantial information to regulate future expression after fertilization. Here we show that most promoters in mouse sperm are flanked by well-positioned nucleosomes marked by active histone ...
Y. Jung   +6 more
semanticscholar   +1 more source

A Surface‐engineered Microfluidic Device for Antibody‐Mediated Negative Selection of High‐Quality Sperm for Assisted Reproduction

open access: yesAdvanced Functional Materials, EarlyView.
This study reports a microfluidic device with a functionalized surface utilizing a polyoxazoline coating and covalently immobilized gold nanoparticles and anti‐phosphatidylserine antibody. The device efficiently eliminates pre‐apoptotic and apoptotic spermatozoa and yields sperm with substantially improved quality and low DNA damage, offering a simple ...
Soraya Rasi Ghaemi   +5 more
wiley   +1 more source

Egg donors’ attitudes toward identifiability, offspring information, and genetic testing

open access: yesReproductive Biology and Endocrinology
Background Research on egg donors’ perspectives regarding identifiability, donor-conceived offspring, and genetic testing remains limited, as most studies have focused on sperm donors.
Emilie Lassen   +3 more
doaj   +1 more source

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