Results 51 to 60 of about 192,203 (268)

Gatekeepers of the Germ Line: How Mitochondria Shape Reproductive Evolution in Metazoans

Biology
Mitochondria play essential roles for animal reproduction, influencing not only cellular energetics but also gamete quality, inheritance and evolutionary patterns.
Yu-Tong Sun, Wan-Xi Yang
doaj   +1 more source

A pathogenic variant in the uncharacterized RNF212B gene results in severe aneuploidy male infertility and repeated IVF failure

HGG Advances, 2023
Summary: Quantitative and qualitative spermatogenic impairments are major causes of men’s infertility. Although in vitro fertilization (IVF) is effective, some couples persistently fail to conceive.
Moran Gershoni, Tslil Braun, Ron Hauser, Shimi Barda, Ofer Lehavi, Mira Malcov, Tsvia Frumkin, Yael Kalma, Shmuel Pietrokovski, Eli Arama, Sandra E. Kleiman   +10 more
doaj   +1 more source

Sperm storage [PDF]

Current Biology, 2012
(Uploaded by Plazi for the Bat Literature Project) No abstract provided.
Orr, Teri J., Zuk, Marlene
openaire   +2 more sources

Strong‐Magnetic Flexible Composites for Magnetically Responsive Soft Robots

Advanced Robotics Research, EarlyView.
This perspective provides an overview of the performance mechanisms, preparation methods, and applications of strong magnetic flexible composite materials in soft actuators (such as gripping, movement, and sensing), and further explores current opportunities and challenges.
Wenwen Li, Shuai Liu, Xinyi Wang, Xinglong Gong, Shouhu Xuan   +4 more
wiley   +1 more source

Redox‐Dependent Chaperoning of GBF1 Condensates Regulates Seed Germination in Arabidopsis

Advanced Science, EarlyView.
In dormant seeds (low ROS), GBF1 forms liquid condensates to repress the germination gene CathB3, and the chaperone GIP1 maintains condensate liquidity and repressive activity. Upon imbibition (high ROS), ROS oxidize GIP1 during germination, impairing its chaperone function.
Yunying Wang, Xiaofeng Fang
wiley   +1 more source

Supramolecular Assembly of Stepped‐Persistent ROS Nanogenerator for Sustained Tumor Immunotherapy

Advanced Science, EarlyView.
ROS catalytic systems often fail to achieve both effective tumor elimination and persistent immune activation due to their monotonous ROS production profiles. A stepped‐persistent ROS nanogenerator was developed by supramolecularly assembling multiple ROS generation modules within a nanofiber structure to simultaneously extend ROS generation duration ...
Zhenqiang Wang, Ming Qin, Wenjing Lai, Shiwen Chen, Fengling Wang, Dandan Xie, Maohua Chen, Changpeng Hu, Kui Wang, Rong Zhang, Guobing Li   +10 more
wiley   +1 more source

Functional remodeling of the gut microbiome and metabolome in primary idiopathic male infertility

BMC Microbiology
Background Primary idiopathic male infertility (PIMI) is a complex condition with unclear biological mechanisms. Increasing evidence indicates that gut microbiome-derived functional and metabolic alterations can influence host physiological processes ...
Chen Luo, Hailin Yao, Yang Xian, Tingting Yang, Xiao Xiao, Lijuan Ying, Jinyan Xu, Xuefeng Luo, Dajian Qiu, Yuan Liu, Bo Liu, Fuping Li   +11 more
doaj   +1 more source

Obstetric and perinatal outcomes in pregnancies conceived with donor versus partner sperm: a systematic review and meta-analysis

Frontiers in Endocrinology
BackgroundMale-related factors contribute to 30-40% of infertility cases, with donor sperm serving as a critical solution for severe male infertility or paternally inherited genetic disorders.
Junjie Liu, Yanpeng Dai, Zuozhe Song, Xintao Sun, Dongdong Lv, Dehua Zhao   +5 more
doaj   +1 more source

Aptamer‐Targeted PrPC Drives Colorectal Cancer Metastasis via a LYN‐STAT3 Complex and Enables Liquid Biopsy Detection

Advanced Science, EarlyView.
The aptamer WHY‐3E identifies PrPC as a CRC driver. Stabilized by USP18, endocytosed PrPC forms a LYN/STAT3 complex, upregulating MSN transcription to promote metastasis. Crucially, WHY‐3E sensitively detects PrPC‐positive circulating exosomes, establishing a robust theoretical foundation for non‐invasive clinical diagnostics.
Chunlin Wang, Hongyu Wu, Chaojing Zheng, Hao Zhang, Xiaoqiu Wu, Jiaqi Wang, Zewen Chang, Jun Xiang, Yunxiao Liu, Chenkai Zhang, Yuliuming Wang, Hao Jiang, Yuchen Zhong, Jun Luo, Ying Chen, NaNa Zhang, Weiyuan Zhang, Ziming Yuan, ChaoXia Zou, Weihong Tan, Meng Wang, Hanqing Hu, Tao Bing, Guiyu Wang   +23 more
wiley   +1 more source

Integrated profiling of semen microbiota and metabolome reveals dysregulation in primary idiopathic male infertility

Journal of Translational Medicine
Background Primary idiopathic male infertility remains a significant challenge due to its complex etiology and the lack of effective diagnostic tools.
Hailin Yao, Chen Luo, Yang Xian, Bo Liu, Tingting Yang, Run Tian, Xiao Xiao, Wenrui Zhao, Lijuan Ying, Jinyan Xu, Shasha Liu, Yelin Jia, Xuefeng Luo, Dajian Qiu, Yuan Liu, Qinqin Wu, Xiaohong Luo, Zhenmi Liu, Fuping Li   +18 more
doaj   +1 more source