Results 31 to 40 of about 192,203 (268)

Comparison of outcomes between pulsatile gonadotropin releasing hormone and combined gonadotropin therapy of spermatogenesis in patients with congenital hypogonadotropic hypogonadism

Reproductive Biology and Endocrinology
Background To evaluate whether there was a difference in outcome between pulsatile gonadotropin releasing hormone (GnRH) therapy and human chorionic gonadotropin/human menopausal gonadotropin (hCG/HMG) therapy for induction of spermatogenesis in post ...
Yi Zheng, Heng-Zhou Bai, Gui-Cheng Zhao, Kun Tian, Jun-Tao Yue, Ding-Ming Li, Xiao-Hui Jiang   +6 more
doaj   +1 more source

Semen parameters are seriously affected in acephalic spermatozoa syndrome

Basic and Clinical Andrology, 2022
Résumé Contexte Des études antérieures ont rapporté que certains patients qui avaient des spermatozoïdes sans tête présentaient une mauvaise qualité du sperme, mais il n’y a eu aucune analyse systématique publiée sur la qualité du sperme chez les ...
Li-juan Ying, Lin Yu, Tingting Yang, Ying-bi Wu, Jin-yan Xu, Ye-lin Jia, Yan Zheng, Fuping Li   +7 more
doaj   +1 more source

Spatiotemporal and quantitative analyses of phosphoinositides – fluorescent probe—and mass spectrometry‐based approaches

FEBS Letters, EarlyView.
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho, Shin Morioka, Junko Sasaki, Takehiko Sasaki   +3 more
wiley   +1 more source

Egg donors’ attitudes toward identifiability, offspring information, and genetic testing

Reproductive Biology and Endocrinology
Background Research on egg donors’ perspectives regarding identifiability, donor-conceived offspring, and genetic testing remains limited, as most studies have focused on sperm donors.
Emilie Lassen, Josephine G. Lemmen, Guido Pennings, Anne-Bine Skytte   +3 more
doaj   +1 more source

PIWIs Regulate Spermatogonia Self-Renewal and Differentiation by Wnt/β-Catenin Signaling Pathway in Eriocheir sinensis

Biology
The roles of PIWI in mammalian spermatogenesis have been well-studied but are largely unknown in invertebrates such as the Chinese mitten crab (Eriocheir sinensis), which produces non-flagellar sperm.
Bang-Hong Wei, Zhan Zhao, Hong-Yu Qi, Zhen-Fang Li, Wan-Xi Yang, Shuang-Li Hao   +5 more
doaj   +1 more source

Identifying transcription factors controlling the basal expression of human MRP4 highlights a substantial role for Sp1

FEBS Open Bio, EarlyView.
The MRP4 transporter exports several drugs and signaling molecules. Here, we identified key promoter elements regulating basal MRP4 expression. Using reporter assays, we defined a conserved region with essential Sp1 and contributory Ets sites, which controlled basal MRP4 expression.
Debora Singer, Angelique Kragl, Katrin Ziems, Juliane Glaubitz, Sophie Grammbauer, Susanne Hildebrandt, Mladen V. Tzvetkov, Gabriele Jedlitschky   +7 more
wiley   +1 more source

Long-Term Follow Up of the Erectile Function of Testicular Cancer Survivors

Frontiers in Endocrinology, 2019
The diagnosis of testicular cancer (TC) can have a considerable and persistent impact on a patient's sexuality, especially given its location. The high prevalence of TC in young adults, and the good prognosis, explain the great interest in sexual ...
Francesco Pallotti, Alessandra Petrozzi, Francesco Cargnelutti, Antonio Francesco Radicioni, Andrea Lenzi, Donatella Paoli, Francesco Lombardo   +6 more
doaj   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

From biological marker to clinical application: the role of anti-Müllerian hormone for delayed puberty and idiopathic non-obstructive azoospermia in males

Endocrine Connections
Anti-Müllerian hormone (AMH), a biomarker secreted by Sertoli cells in the testes, has emerged as a critical indicator of male reproductive function with significant clinical application potential.
Yuanyuan Zeng, Guicheng Zhao, Yi Zheng, Xiaohui Jiang   +3 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source