Results 211 to 220 of about 273,320 (297)

Innate immunity shapes the persistent transmission of plant viruses by insect vectors

New Plant Protection, EarlyView.
In this review, we focus on two key aspects of the virus–vector interplay: (1) persistently transmitted viruses utilize host factors to overcome transmission barriers; and (2) molecular recognition activates antiviral immunity and subsequent viral counter‐defense. Understanding these interactions offers critical insights for developing novel strategies
Gang Lu, Chuanxi Zhang, Junmin Li
wiley   +1 more source

Multiple Roles of Protamine Kinase SRPK1 and Phosphatase PP1γ in Sperm Development

PROTEOMICS, EarlyView.
ABSTRACT Protein phosphorylation regulates key events of male germ cell differentiation. In the testis, SRPK1 and PP1γ are involved in protamine phosphorylation and dephosphorylation, respectively, and their deregulation is linked to defective chromatin structure and male infertility.
Alberto de la Iglesia, Mélina Blanco, Meritxell Jodar, Olivier Feudjio, Marjorie Leduc, Judit Castillo, Julie Cocquet, Rafael Oliva   +7 more
wiley   +1 more source

Epigenetic Regulation of Immune Dysfunction in Chronic Prostatitis/Chronic Pelvic Pain Syndrome

The Prostate, EarlyView.
ABSTRACT Background Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a prevalent and debilitating condition with unclear etiology. Increasing evidence implicates immune dysregulation, yet the molecular mechanisms underlying impaired immune regulation remain poorly defined. This study investigated the role of altered immune responses within
Praveen Thumbikat, Goutham Pattabiraman, Farzaneh Sharifzad, Yongyong Yang, Zhiqiang Liu, Catherine V. Osborn, Stephen F. Murphy, Qi Cao, Anthony J. Schaeffer   +8 more
wiley   +1 more source

Dietary restriction induces persistent multigenerational phenotypic effects in Phytoseiulus persimilis

Pest Management Science, EarlyView.
The study shows ancestral dietary restriction in Phytoseiulus persimilis produces persistent, sex‐specific, multi‐generational effects on survival and body size, with stronger maternal than paternal lineage influences despite nutritional recovery. Abstract BACKGROUND Transgenerational phenotypic plasticity (TGP) allows environmental effects to persist ...
Xia Chen, Keshi Zhang, Xiao Han, Yun Xu, Zhi‐Qiang Zhang   +4 more
wiley   +1 more source

Safety Evaluation of an Aqueous Root and Leaf Extract of Ashwagandha (Withania somnifera)

Phytotherapy Research, EarlyView.
Sensoril, an aqueous root and leaf extract of ashwagandha showed no evidence of mutagenicity in the in vitro Ames assay, was negative in the in vitro micronucleus, in vivo mammalian bone marrow chromosome aberration assays, and was well tolerated in the rat at up to 4000 mg/kg BW/day when administered orally for a period of 90 days. The data from these
Mukesh Summan, Candace L. Doepker, Gregory P. Brorby   +2 more
wiley   +1 more source

Gonadotropin Stimulation Before Sperm Retrieval in Non-Obstructive Azoospermia: Myth, Magic, or Medicine? [PDF]

Int Braz J Urol
Viana MC, Achermann APP, Andrade DL, Miyaoka R, Esteves SC.   +4 more
europepmc   +1 more source

The scale matters: A review on stimuli‐responsive microrobots categorized by scale for biomedical applications

Responsive Materials, EarlyView.
We systematically summarize how each scale dictates fundamental choices in design feature, manufacturing technology, driving mechanism, and control strategy, which are inherently governed by scale‐dominated physical principles. Furthermore, the application of scale‐determined operation modes of microrobots across different stages of medical ...
Hang Yin, Yujing Li, Guanghao Wu, Yubing Guo   +3 more
wiley   +1 more source

Effects of N-acetyl-L-cysteine on sperm quality during chilled storage of Maguan hornless goat semen. [PDF]

PLoS One
Xu H, Cao M, Wang Q, Ju Y, Wang X, Liu Q, Zeng T, Chen X.   +7 more
europepmc   +1 more source

Precise 3D Tracking of Highly Non‐Planar Eukaryotic Flagellar Beating Patterns Using Digital Holographic Microscopy

Small Methods, EarlyView.
The 3D beating dynamics of eukaryotic flagella drive motility, sensory functions, and resource acquisition, yet highly non‐planar beating patterns remain poorly characterized. Based on Digital Holographic Microscopy, holoV3C enables label‐free 3D reconstruction of such complex dynamics with 53 nm axial resolution, demonstrated on mouse sperm and ...
Patryk Nienaltowski, Jonasz Słomka, Federica Miano, Thomas Kiørboe, Clara Martínez‐Pérez, Tristan Colomb, Yves Emery, Roman Stocker   +7 more
wiley   +1 more source

Exploring the Impact of Polystyrene Microplastic Beads on Male Gonads of the Marine Mussel, Mytilus galloprovincialis

Environmental Toxicology, EarlyView.
ABSTRACT Plastic, with its remarkable versatility and numerous applications, has greatly benefited humanity. However, its extreme resistance to natural degradation means it persists in the environment for long periods, causing global environmental problems.
Teresa Chianese, Mariachiara Galati, Tiziana Cappello, Maria Maisano, Gennaro Lettieri, Carmela Marinaro, Marina Piscopo, Gianluca Fasciolo, Carlos Gravato, Gaetana Napolitano, Giulia Paolella, Annamaria Locascio, Rosaria Scudiero, Luigi Rosati   +13 more
wiley   +1 more source