Results 71 to 80 of about 109,348 (344)
CellPolaris decodes how transcription factors guide cell fate by building gene regulatory networks from transcriptomic data using transfer learning. It generates tissue‐ and cell‐type‐specific networks, identifies master regulators in cell state transitions, and simulates TF perturbations in developmental processes.
Guihai Feng +27 more
wiley +1 more source
Decline in human sperm counts during the past 50 years? [PDF]
There is widespread concern that environmental pollutants acting as xenoestrogens may affect human fertility adversely. Whether this has already made an impact on human fertility worldwide remains debatable at the present stage.
Jayachandra, Srinivasa +2 more
core
Nurr1 Orchestrates Claustrum Development and Functionality
Nurr1 (Nr4a2) is the master transcription factor to control claustrum morphogenesis and cell fate decision postmitotically by inhibiting intracellular G‐protein signaling. Nurr1 deficiency alters the transcriptomic profiles of subcortical claustral neurons into neocortical insular neurons, resulting in defected claustrum development, impaired axonal ...
Kuo Yan +12 more
wiley +1 more source
Toxicity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in the developing male Wistar(Han) rat II: chronic dosing causes developmental delay [PDF]
We have investigated whether fetal exposure to 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) causes defects in the male reproductive system of the rat, using chronically exposed rats to ensure continuous exposure of the fetus. 5-6 week old rats were exposed
Bell, David Robert +11 more
core +1 more source
Genome‐wide, high‐resolution profiling of hydroxymethylation in mouse SCNT embryos reveals a transient, allele‐symmetric 5hmC reprogramming pattern distinct from natural embryos, with X‐chromosomes and imprinting control regions resistant to proper remodeling.
Zeming Xiang +9 more
wiley +1 more source
Risultati del trattamento chirurgico del varicocele nella infertilità maschile [PDF]
To evaluate the results of surgical treatment of varicocele on infertile men, especially regarding sperm count, 245 patients, surgically treated from 1993 to 2003, were evaluated.
Borghese, Mario +4 more
core
Snord17, through interaction with Thoc3, promotes nuclear export and translation of Yy2 mRNA in Snord17+/+ ISCs. The Yy2 protein subsequently binds the Tead4 promoter to promote its transcription, activating Hippo signaling, which is essential for ISC maintenance.
Peikang Zhang +10 more
wiley +1 more source
Background: Sperm morphology has been strongly linked to fertilization. This makes it an important component in semen analysis. They are usually assessed by world health organization (WHO) standard or Kruger strict criteria in in-vitro fertilization (IVF)
Faduola Paul +2 more
doaj
Protective Effect of All-Trans Retinoic Acid in Cisplatin-Induced Testicular Damage in Rats
Purpose: To investigate the effects of all-trans retinoic acid (ATRA) in cisplatin (CP)-induced testicular damage in rats. Materials and Methods: Twenty-eight male Wistar rats were divided into four groups: Control, ATRA alone, ATRA+CP, and CP alone ...
Cem Yucel +10 more
doaj +1 more source
Effects of cryopreservation on performance and fertilizing ability of sperm from Kerai (Puntius daruphani) [PDF]
Puntius daruphani broodstocks bought from fishermen in Temerloh, Pahang, conditioned in the Hatchery Unit of Universiti Putra Malaysia were used for all the experiments. In this study fresh and cryopreserved sperm of P.
Emhemed, Mohamed M. M.
core

