Results 101 to 110 of about 14,069,776 (341)
Advanced Science, EarlyView.UBE2O targets CDKL1 for the degradation to upregulate PD‐L1 expression and promotes resistance to radioimmunotherapy in lung cancer, supporting the potential of targeting UBE2O as a promising therapeutic strategy. ABSTRACT Resistance to radioimmunotherapy is one of the primary causes of treatment failure in lung cancer patients; however, the underlying
Huichan Xue +6 more
wiley +1 more source
Animal, 2014 Cholesterol-loaded cyclodextrins (CLC) added to the sperm before cryopreservation enhance sperm quality after freeze-thawing in several cold shock-sensitive species, including cattle and goats.
E. Mocé +3 more
doaj +1 more source
Rheotaxis facilitates upstream navigation of mammalian sperm cells [PDF]
, 2014 A major puzzle in biology is how mammalian sperm maintain the correct swimming direction during various phases of the sexual reproduction process. Whilst chemotaxis may dominate near the ovum, it is unclear which cues guide spermatozoa on their long ...
Dunkel, Jörn +8 more
core +1 more source
OpenCASA: A new open-source and scalable tool for sperm quality analysis
PLoS Comput. Biol., 2019 In the field of assisted reproductive techniques (ART), computer-assisted sperm analysis (CASA) systems have proved their utility and potential for assessing sperm quality, improving the prediction of the fertility potential of a seminal dose.
Carlos Alquézar-Baeta +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study shows that in glioma stem cells (GSCs), RBM12 recruits ALKBH5 to remove m6A from SLC7A5 transcripts, thereby enhancing mRNA stability, which elevates large neutral amino acid (LNAA) levels and activates mTORC1, promoting GSC proliferation, self‐renewal, and tumor growth.
Hong Lei +18 more
wiley +1 more source
EBV induced loss of sperm quality
Urology Research and Practice, 2021 Objective: To analyze the presence of Epstein–Barr-virus (EBV) in sperm samples from patients diagnosed with some impairment of the fertility parameters evaluated using seminogram and to observe if there is any difference with the normozoospermic samples.
Manuel, Huerta +7 more
openaire +2 more sources
The KIF6‐RBP Complex Orchestrates mRNA Transport Required for Sperm Flagellar Assembly
Advanced Science, EarlyView.Two homozygous deleterious KIF6 variants are identified in unrelated men with impaired sperm motility. Mouse models and multi‐omics analyses reveal that KIF6 cooperates with the RNA‐binding proteins FMRP and FXR1 to deliver mRNAs essential for sperm flagellar assembly, linking disrupted mRNA transport to reduced abundance of key structural and ...
Chunbo Xie +20 more
wiley +1 more source
Semen quality detection using acoustic wave sensors [PDF]
, 2011 Artificial insemination (AI) is a widely used part of the modern agricultural industry, with the number of animals inseminated globally being measured in the millions per anum.
Atherton, S
core
Advanced Science, EarlyView.eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu +12 more
wiley +1 more source
Differential sperm expenditure reveals a possible role for post-copulatory sexual selection in a lekking moth [PDF]
, 2013 Cordes N, Yiğit A, Engqvist L, Schmoll T. Differential sperm expenditure reveals a possible role for post-copulatory sexual selection in a lekking moth. Ecology and Evolution.
Yiğit, Arzu +7 more
core +1 more source