Results 101 to 110 of about 216,508 (311)

Medical treatment to improve sperm quality

Reproductive BioMedicine Online, 2006
Approximately 30% of cases of couple infertility are due to a male factor. Several conditions can interfere with spermatogenesis and reduce sperm quality and production. Treatable conditions, such as hypogonadism, varicocele, infections and obstructions, should be diagnosed and corrected, but many aspects of male factor infertility remain unclear ...
ISIDORI, Andrea, POZZA, CARLOTTA, GIANFRILLI, DANIELE, Aldo Isidori   +3 more
openaire   +2 more sources

Directed Evolution Improves the Catalytic Efficiency of APEX2‐Mediated Proximity‐Dependent RNA Labeling

Advanced Science, EarlyView.
ABSTRACT Engineered ascorbate peroxidase APEX2 has been widely used for spatially restricted profiling of subcellular biomolecules, but its catalytic efficiency toward newly developed probes such as biotin‐aniline (Btn‐An) remains suboptimal. To overcome this limitation, we performed yeast surface display‐based directed evolution to enhance APEX2 ...
Gang Wang, Yi Li, Peiyuan Meng, Peng Zou
wiley   +1 more source

Factors affecting sperm recovery rates and survival after centrifugation of equine semen [PDF]

, 2012
Conventional centrifugation protocols result in important sperm losses during removal of the supernatant. In this study, the effect of centrifugation force (400 or 900 × g), duration (5 or 10 min), and column height (20 or 40 mL; Experiment 1); sperm ...
Eilts, B. E., Eljarrah, A. H., Ferrer, Maria S., Lyle, S. K., Paccamonti, D. L.   +4 more
core   +2 more sources

The Landscape and Regulation of Histone Crotonylation in Mammalian Gametes and Early Embryos

Advanced Science, EarlyView.
Histone crotonylation undergoes a genome‐wide transition from broad domains to canonical narrow peaks during minor zygotic genome activation (ZGA). This remodeling is required for proper major ZGA and blastocyst formation. Disruption of this transition by transcriptional inhibition, metabolic perturbation, or HDAC1 dysfunction impairs embryonic ...
Shenli Yuan, Yelian Yan, Yalin Liang, Kanghua Zhong, Zhican Fu, Xiaobo Wang, Chao Liu, Tao Huang, Keliang Wu   +8 more
wiley   +1 more source

Paternal Caffeine Exposure Programs Offspring Stress Vulnerability via Sperm Dlk1‐Dio3 Imprinting‐Directed Remodeling of a Novel Neural Circuit

Advanced Science, EarlyView.
The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu, Gaole Dai, Sen Zhu, Shuai Zhang, Tingting Wang, Yuan Meng, Fang Yang, Xiaoyi Han, Hui Wang, Hao Kou, Dan Xu   +10 more
wiley   +1 more source

Depolarization of sperm membrane potential is a common feature of men with subfertility and is associated with low fertilization rate at IVF [PDF]

, 2016
STUDY QUESTION. Are significant abnormalities in outward (K+) conductance and resting membrane potential (Vm) present in the spermatozoa of patients undertaking IVF and ICSI and if so, what is their functional effect on fertilization success?
Barratt, Christopher L. R., Brown, Sean G., Lishko, Polina V., Mansell, Steven A., Martins da Silva, Sarah, Publicover, Stephen J., Ramalingam, Mythili, Sutton, Keith A., Williams, Hannah L., Wilson, Stuart M.   +9 more
core   +6 more sources

Design, Control, and Clinical Applications of Magnetic Actuation Systems: Challenges and Opportunities

Advanced Intelligent Systems, Volume 7, Issue 3, March 2025.
This review aims to provide a broad understanding for interdisciplinary researchers in engineering and clinical applications. It addresses the development and control of magnetic actuation systems (MASs) in clinical surgeries and their revolutionary effects in multiple clinical applications.
Yingxin Huo, Lidong Yang, Tiantian Xu, Dong Sun   +3 more
wiley   +1 more source

Sperm DNA damage and disturbed chromatin condensation indexes (DFI and CMA3) in normozoospermic men with unexplained infertility problem

The Aging Male
Purpose The quantitatively measured sperm DNA damage and disturbed chromatin condensation indexes (%DNA fragmentation index [DFI%] and %high DNA staining index [%HDS]) and their relationships with sperm quality in normospermic men with unexplained ...
Mehdi Abedinzadeh, Sara Abedinzadeh, Fatemeh Sadeghi-Nodoushan, Fatemeh Pourrajab   +3 more
doaj   +1 more source

Reproductive traits in Ethiopian male goats [PDF]

, 2007
This thesis characterizes reproductive traits of Ethiopian male goats raised under extensive husbandry and subjected to differential nutritional management.
Mekasha Gebre, Yoseph
core  

MTCA‐Net: Multi‐Task Cascade Analysis Network for Real‐Time Sperm Quality Analysis

Advanced Intelligent Systems, EarlyView.
This article proposes MTCA‐Net, a multi‐task cascaded analysis network for real‐time sperm quality assessment in intracytoplasmic sperm injection. The framework integrates detection, tracking, and segmentation modules to jointly analyze sperm morphology and motility.
Jiajin Li, Wenwen Sun, Jun He, Xinyu Fan, Xuecheng Ge, Fengya Lu, Yadan Wang, Yi Wang, Zhiguo Zhang, Qibing Wu, Jinhua Zhou   +10 more
wiley   +1 more source