Results 81 to 90 of about 7,144,982 (296)

Functional Sex Reversal in Adult Gonochoristic Teleosts is Mediated by Ovarian Germline Stem Cell Plasticity and Somatic Cell Transdifferentiation

open access: yesAdvanced Science, EarlyView.
Oocytes play crucial roles in maintaining ovarian fate in adult gonochoristic fish. Targeted oocyte ablation with aromatase inhibition triggers the activation of surviving germline stem cells and the transdifferentiation of somatic cells from granoulosa/theca to Sertoli/Leydig lineages, inducing a complete and functional female‐to‐male sex reversal ...
Yang Yang   +6 more
wiley   +1 more source

Effect of cholesterol-loaded cyclodextrins on bull and goat sperm processed with fast or slow cryopreservation protocols

open access: yesAnimal, 2014
Cholesterol-loaded cyclodextrins (CLC) added to the sperm before cryopreservation enhance sperm quality after freeze-thawing in several cold shock-sensitive species, including cattle and goats.
E. Mocé   +3 more
doaj   +1 more source

RNA Promotes Synapsin Condensates That Organize Synaptic Vesicles in Live Neurons and Enable Localized Translation in Reconstituted System

open access: yesAdvanced Science, EarlyView.
Condensates at synapses organize synaptic vesicles (SVs) and are crucial for efficient neurotransmitter release, yet how RNA contributes to this mesoscale architecture remains poorly understood. Here we uncover that RNA modulates synapsin–driven condensates.
Branislava Rankovic   +21 more
wiley   +1 more source

EBV induced loss of sperm quality

open access: yesUrology Research and Practice, 2021
Objective: To analyze the presence of Epstein–Barr-virus (EBV) in sperm samples from patients diagnosed with some impairment of the fertility parameters evaluated using seminogram and to observe if there is any difference with the normozoospermic samples.
Manuel, Huerta   +7 more
openaire   +2 more sources

BOULE is Essential for the Dynamic Disassembly of Heat Shock Granules in Male Germ Cells

open access: yesAdvanced Science, EarlyView.
BOULE orchestrates stress granule disassembly in germ cells via a two‐pronged mechanism: it promotes G3BP1 ubiquitination by upregulating TRIM27, generating a signal for VCP/FAF2 recruitment, and it maintains G3BP1 and FAF2 protein levels. BOULE deficiency disrupts disassembly complex formation, leading to impaired heat shock granule clearance ...
Xin Li   +8 more
wiley   +1 more source

RSF1‐Dependent PAR Turnover Promotes 53BP1 Liquid Condensate Formation at DNA Damage Sites

open access: yesAdvanced Science, EarlyView.
At sites of DNA damage, RSF1 recruits PARG to accelerate PAR turnover, triggering a switch from PAR‐driven condensates to 53BP1 condensates. This condensate transition enables p53‐dependent gene transcription and coordinates the DNA damage response.
Yungyeong Heo   +10 more
wiley   +1 more source

A Magnetic‐Driven Self‐Rotation‐Stabilized Miniature Swimming Robot

open access: yesAdvanced Science, EarlyView.
Inspired by the stable rotational descent of seeds in nature, this study designs a magnetic‐driven self‐rotation‐stabilized miniature swimming robot (MSMSR). Based on a resonance‐driven strategy, the robot exhibits high swimming performance, offering enhanced directional swimming and improved resistance to water flow disturbances compared to existing ...
Fujun Wang   +4 more
wiley   +1 more source

Association between hypo-osmotic swelling test-induced tail swelling patterns and sperm quality

open access: yesFuture Science OA
Aim: The current sperm selection procedure for intracytoplasmic sperm injection has limited ability to detect structural and functional abnormalities of the spermatozoa.
Salima Daoud   +5 more
doaj   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

A general description of additive and non-additive elements of sperm competitiveness and their relation to male fertilization success [PDF]

open access: yes, 2013
Engqvist L. A general description of additive and non-additive elements of sperm competitiveness and their relation to male fertilization success. Evolution.
Engqvist, Leif   +1 more
core   +1 more source

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