Results 51 to 60 of about 504,977 (225)

Seminal plasma extracellular vesicles tRF-Val-AAC-010 can serve as a predictive factor of successful microdissection testicular sperm extraction in patients with non-obstructive azoospermia

open access: yesReproductive Biology and Endocrinology, 2022
Background There is a lack of biomarkers for distinguishing non-obstructive azoospermia (NOA) patients with successful sperm retrieval (Sp+) from those with failed sperm retrieval (Sp-).
Xiaoxiao Han   +10 more
doaj   +1 more source

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

A comprehensive assessment of predictors of fertility outcomes in men with non-obstructive azoospermia undergoing microdissection testicular sperm extraction

open access: yesReproductive Biology and Endocrinology, 2020
Background Microdissection testicular sperm extraction (microTESE) in men with non-obstructive azoospermia (NOA) is the procedure that results in the highest number of sperm cells retrieved for in vitro fertilization (IVF).
Parviz K. Kavoussi   +9 more
doaj   +1 more source

Genetic variance and genotype reaction norms in response to larval food manipulation for a trait important in scorpionfly sperm competition. [PDF]

open access: yes, 2008
Engqvist L. Genetic variance and genotype reaction norms in response to larval food manipulation for a trait important in scorpionfly sperm competition. Functional Ecology. 2008;22(1):070915213639001-???Sperm competition is an important attribute of many
L. Engqvist   +1 more
core   +1 more source

WFS1 Deficiency Impairs PIAS4‐Associated SUMOylation and Increases Ubiquitin‐Mediated Spermatogenesis‐Related Protein Degradation Leading to Testicular Male Infertility

open access: yesAdvanced Science, EarlyView.
The findings establish a critical role for WFS1 in human male fertility. Mechanistically, WFS1 interacts with PIAS4 to promote the SUMOylation of key spermatogenesis‐associated proteins, which in turn competitively inhibits their K48‐linked ubiquitin‐mediated degradation during spermatogenesis.
Yunchuan Tian   +14 more
wiley   +1 more source

Office-based sperm retrieval for treatment of infertility.

open access: yes, 2013
This article describes sperm retrieval procedures that may be performed in an office setting. Indications for sperm retrieval, preprocedural preparation, and anesthetic considerations are discussed.
Khurana, Kiranpreet, MD   +1 more
core   +1 more source

Building families—Implementing balanced sexual and reproductive health

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract One of the main initiatives of the World Health Organization (WHO) is the promotion of Sexual and Reproductive Health (SRH). Sexuality, infertility, and contraception are three interconnected pillars of SRH, each essential for achieving global equity in family planning and family building.
Peter Y. Liu   +9 more
wiley   +2 more sources

Innovations in surgical management of nonobstructive azoospermia

open access: yesIndian Journal of Urology, 2016
Testicular sperm extraction (TESE) technique and intra-cytoplasmic sperm injection are breakthrough fertility treatments for men with nonobstructive azoospermia (NOA).
Renzhong Ran   +2 more
doaj   +1 more source

Utility of micro-TESE in the most severe cases of non-obstructive azoospermia

open access: yesUpsala Journal of Medical Sciences, 2020
The use of intracytoplasmic sperm injection (ICSI) has been a major breakthrough in the treatment of male infertility. Even patients with non-obstructive azoospermia (NOA) may benefit from the ICSI technique to father a child as long as spermatogenesis ...
Göran Westlander
doaj   +1 more source

Surgical sperm retrieval: Techniques and their indications

open access: yes, 2011
Men with azoospermia can father a child through intra-cytoplasmic sperm injection if sperm can be retrieved from their epididymis or testis. Several percutaneous and open surgical procedures have been described to retrieve sperm.
Rupin Shah
core   +1 more source

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