Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li +5 more
wiley +1 more source
Novel methods to enhance surgical sperm retrieval: a systematic review
Objectives: To explore the use of novel technologies in sperm retrieval in men with azoospermia due to a production defect. Methods: We performed a Preferred Reporting Items for Systemic Reviews and Meta-Analysis (PRISMA)-compliant systemic literature ...
Efimenko, Iakov +4 more
core +2 more sources
Background Microdissection testicular sperm extraction (microTESE) in men with non-obstructive azoospermia (NOA) is the procedure that results in the highest number of sperm cells retrieved for in vitro fertilization (IVF).
Parviz K. Kavoussi +9 more
doaj +1 more source
Practical problems in the posthumous retrieval of sperm [PDF]
This communication discusses the practical problems that arise during the collection and processing of sperm that have been retrieved posthumously. It is based on a small group, namely the last six men from whom we carried out posthumous retrieval. The reason for each retrieval, the method of that retrieval, the assessment of the sperm retrieved, the ...
Anne M, Jequier, Melissa, Zhang
openaire +2 more sources
PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian +13 more
wiley +1 more source
Innovations in surgical management of nonobstructive azoospermia
Testicular sperm extraction (TESE) technique and intra-cytoplasmic sperm injection are breakthrough fertility treatments for men with nonobstructive azoospermia (NOA).
Renzhong Ran +2 more
doaj +1 more source
Utility of micro-TESE in the most severe cases of non-obstructive azoospermia
The use of intracytoplasmic sperm injection (ICSI) has been a major breakthrough in the treatment of male infertility. Even patients with non-obstructive azoospermia (NOA) may benefit from the ICSI technique to father a child as long as spermatogenesis ...
Göran Westlander
doaj +1 more source
Development of a nomogram for sperm retrieval at microTESE for idiopathic non-obstructive azoospermia in a multi-center cohort study. [PDF]
Abstract Background Non‐obstructive azoospermia (NOA) affects approximately 10% of infertile men and represents a major challenge in assisted reproductive technology (ART). A model that includes histological variants could be helpful in predicting sperm retrieval rate (SRR) after microdissection testicular sperm extraction (mTESE) in patients affected ...
Russo GI +10 more
europepmc +2 more sources
Sperm recovery and IVF outcome after surgical sperm retrieval in azoospermia: our experience
Background: In the last decade, male factor infertility has been recognized as a significant global problem, which is on an increase. Till date, very few options are available for ameliorating male factor infertility.
Seema Rai +5 more
core +1 more source
Request for posthumous fatherhood with perimortem surgical sperm retrieval
This chapter includes clinical cases, background, evidence‐based practical management options, preventive measures, key‐point summaries of posthumous fatherhood with perimortem surgical sperm retrieval and answers to questions patients ask.
Pagani, Rodrigo L +9 more
core +1 more source

