Results 61 to 70 of about 20,361 (253)

Xenogeneic Mitochondrial Transplantation Improves Selected Age‐Associated Phenotypes in Mice

open access: yesAdvanced Science, EarlyView.
Yak‐derived xenogeneic mitochondrial transplantation improves selected age‐associated phenotypes in mice, enhances mitochondrial functional readouts, and engages host mitochondrial quality‐control pathways. Broad tissue biodistribution, increased ATP production and mtDNA copy number, reduced ROS levels and dysfunctional mitochondria, improved motility ...
Wenpeng Li   +5 more
wiley   +1 more source

Novel methods to enhance surgical sperm retrieval: a systematic review

open access: yes
Objectives: To explore the use of novel technologies in sperm retrieval in men with azoospermia due to a production defect. Methods: We performed a Preferred Reporting Items for Systemic Reviews and Meta-Analysis (PRISMA)-compliant systemic literature ...
Efimenko, Iakov   +4 more
core   +2 more sources

A comprehensive assessment of predictors of fertility outcomes in men with non-obstructive azoospermia undergoing microdissection testicular sperm extraction

open access: yesReproductive Biology and Endocrinology, 2020
Background Microdissection testicular sperm extraction (microTESE) in men with non-obstructive azoospermia (NOA) is the procedure that results in the highest number of sperm cells retrieved for in vitro fertilization (IVF).
Parviz K. Kavoussi   +9 more
doaj   +1 more source

Practical problems in the posthumous retrieval of sperm [PDF]

open access: yesHuman Reproduction, 2014
This communication discusses the practical problems that arise during the collection and processing of sperm that have been retrieved posthumously. It is based on a small group, namely the last six men from whom we carried out posthumous retrieval. The reason for each retrieval, the method of that retrieval, the assessment of the sperm retrieved, the ...
Anne M, Jequier, Melissa, Zhang
openaire   +2 more sources

PDIA6–SCD1 Axis Rewires Lipid Metabolism to Drive Gastric Cancer Progression

open access: yesAdvanced Science, EarlyView.
Protein disulfide isomerase A6 (PDIA6) is identified as an oncogenic driver in gastric cancer. PDIA6 directly binds and stabilizes SCD1 by limiting its ubiquitin–proteasome‐mediated degradation, thereby sustaining monounsaturated fatty acid (MUFA)‐enriched lipid homeostasis and lipid metabolic reprogramming.
Zhen Tian   +13 more
wiley   +1 more source

Innovations in surgical management of nonobstructive azoospermia

open access: yesIndian Journal of Urology, 2016
Testicular sperm extraction (TESE) technique and intra-cytoplasmic sperm injection are breakthrough fertility treatments for men with nonobstructive azoospermia (NOA).
Renzhong Ran   +2 more
doaj   +1 more source

Utility of micro-TESE in the most severe cases of non-obstructive azoospermia

open access: yesUpsala Journal of Medical Sciences, 2020
The use of intracytoplasmic sperm injection (ICSI) has been a major breakthrough in the treatment of male infertility. Even patients with non-obstructive azoospermia (NOA) may benefit from the ICSI technique to father a child as long as spermatogenesis ...
Göran Westlander
doaj   +1 more source

Development of a nomogram for sperm retrieval at microTESE for idiopathic non-obstructive azoospermia in a multi-center cohort study. [PDF]

open access: yesAndrology
Abstract Background Non‐obstructive azoospermia (NOA) affects approximately 10% of infertile men and represents a major challenge in assisted reproductive technology (ART). A model that includes histological variants could be helpful in predicting sperm retrieval rate (SRR) after microdissection testicular sperm extraction (mTESE) in patients affected ...
Russo GI   +10 more
europepmc   +2 more sources

Sperm recovery and IVF outcome after surgical sperm retrieval in azoospermia: our experience

open access: yes, 2018
Background: In the last decade, male factor infertility has been recognized as a significant global problem, which is on an increase. Till date, very few options are available for ameliorating male factor infertility.
Seema Rai   +5 more
core   +1 more source

Request for posthumous fatherhood with perimortem surgical sperm retrieval

open access: yes, 2021
This chapter includes clinical cases, background, evidence‐based practical management options, preventive measures, key‐point summaries of posthumous fatherhood with perimortem surgical sperm retrieval and answers to questions patients ask.
Pagani, Rodrigo L   +9 more
core   +1 more source

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