Results 51 to 60 of about 17,497 (237)

Sertoli Cell‐Derived Extracellular Vesicles Orchestrate Cadmium‐Induced Testicular Inflammation and Fibrosis

Advanced Science, EarlyView.
Environmental cadmium exposure disrupts testicular homeostasis through a novel intercellular communication axis. Stressed Sertoli cells release extracellular vesicles carrying damage‐associated molecular patterns and mitochondrial fragments, which activate macrophages via TLR4/NF‐κB signaling.
Jianfeng Ma, Mailin Gan, Shuang Liang, Siyu Chen, Ziling Hao, Yiting Yang, Jiawei Lu, Qihang Wu, Yuqian Shi, Lijun Sun, Jiaxin Li, Saihao Wang, Yan Wang, Xiaofeng Zhou, Lei Chen, Ye Zhao, Li Zhu, Linyuan Shen   +17 more
wiley   +1 more source

Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis

Animal Research and One Health, EarlyView.
Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang, Tianqi Jin, Zexin Chen, Ye Gong, Qimin Liu, Zifang Wu, Heran Cao, Yan Li, Yuyan Liu, Tianhao Yang, Zhihong Jiang, Wuzi Dong   +11 more
wiley   +1 more source

The impact of hydroalcoholic extracts of Peganum harmala and Piper longum on pituitary- gonad axis hormone levels of male NMRI mice

یافته‌های نوین در علوم زیستی, 2017
Several therapeutic effects have been reported for Peganum harmala and Piper longum. These plants contain flavonoids that probably can affect reproductive endocrine system and reduce fertility.
Namdar Yousefvand, Delaram Eslimi Esfahani, Tayebeh Bahrami   +2 more
doaj  

Cytofluorometric analysis of spermatocytic seminoma [PDF]

Cancer, 1993
Whether spermatocytic seminoma (SS) develops during meiosis or not is still controversial. To determine that, the DNA content of large, small, and intermediate cells of SS was measured by cytofluorometry to obtain DNA histograms for each cell type. The large cells were aneuploid and showed cell cycles with G0/G1 DNA values from 3C to 18C. The ploidy of
H, Takahashi, S, Aizawa, E, Konishi, M, Furusato, H, Kato, T, Ashihara   +5 more
openaire   +2 more sources

Chromatin condensation during Drosophila spermiogenesis and decondensation after fertilization. [PDF]

, 2005
Eine typische Eigenschaft der männlichen Keimzellen ist die Kondensation des Chromatins. Während in Säugern bekannt ist, dass in der Spermiogenese die Histone zuerst durch Transitionsproteine und dann durch Protamine ersetzt werden, ist in Drosophila ...
Jayaramaiah Raja, Sunil, Renkawitz-Pohl, Renate   +1 more
core   +1 more source

Histological Characterization and Comparative Transcriptomic Analysis of Gonads During Early Sex Differentiation in the Northern Snakehead (Channa argus)

Animal Research and One Health, EarlyView.
This study delineates the early sex differentiation timeline in the northern snakehead (Channa argus). These findings provide a foundation for future sex‐control breeding in this economically important species. ABSTRACT The northern snakehead (Channa argus) is an economically important aquaculture species in China.
Chaonan Sun, Donglei Sun, Haishen Wen, Xin Qi, Chao Li, Xiaoyan Zhang, Yun Li   +6 more
wiley   +1 more source

Two waves of de novo methylation during mouse germ cell development [PDF]

, 2014
During development, mammalian germ cells reprogram their epigenomes via a genome-wide erasure and de novo rewriting of DNA methylation marks. We know little of how methylation patterns are specifically determined.
Aravin, A. A., Falciatori, I., Hannon, G. J., Hodges, E., Marran, K., McCombie, W. R., Molaro, A., Rafii, S., Smith, A. D.   +8 more
core   +2 more sources

Heat Stress in Quail: Impacts on Health and Productivity, and Mitigation Strategies

Animal Research and One Health, EarlyView.
Heat stress disrupts physiological homeostasis in quail, inducing oxidative stress, immune dysregulation, and metabolic imbalance, which impair growth, reproduction, product quality, and welfare. Integrating nutritional, environmental, and genetic–epigenetic strategies enhances thermotolerance, sustains productivity, and supports climate‐smart quail ...
T. A. Eletu, I. A. Anjola, L. O. Fasasi, D. P. Fadipe, A. T. Afuye, F. O. Fasanya, O. E. Oke   +6 more
wiley   +1 more source

Transcriptional Inhibition of lncRNA gadd7 by CRISPR/dCas9-KRAB Protects Spermatocyte Viability

Frontiers in Molecular Biosciences, 2021
Our previous study found that lncRNA gadd7 was up-regulated in the semen of varicocele patients, and could promote the apoptosis of mouse spermatocytes and inhibit their proliferation.
Jun Zhao, Wenmin Ma, Yucheng Zhong, Hao Deng, Bingyu Zhou, Yaqin Wu, Meiqiong Yang, Huan Li   +7 more
doaj   +1 more source

Spermatocytic Seminoma in the Rat [PDF]

Toxicologic Pathology, 1985
During the necropsy of a 2-yr-old untreated control rat from a carcinogenicity study, a tan brown nodular mass was observed within the tunica albuginea of one testis. Both testes were processed for light and transmission electron microscopy. Histologically, the testicular mass was composed of round to polyhedral cells with distinct cell boundaries ...
S N, Kim, J E, Fitzgerald, F A, De La Iglesia   +2 more
openaire   +2 more sources