Results 41 to 50 of about 12,760 (248)
, 2023 Conserved PUF (Pumilio and FBF) proteins repress the translation by binding to its target mRNA 3’ untranslated region (3’UTR). C. elegans has 11 PUF proteins. Among them, we focused on two FBFs (FBF-1 and FBF-2) and PUF-8.
Park, Youngyong +1 more
core
Asian Journal of Andrology, 2015 In this experimental prospective study, we aimed to analyze the effect of transient scrotal hyperthermia on the male reproductive organs, from the perspective of sperm parameters, semen plasma biochemical markers, and oxidative stress, to evaluate ...
Meng Rao +6 more
doaj +1 more source
Advanced Science, EarlyView.Stem cell differentiation follows a conserved surface condensate trajectory: H3K27ac super enhancers nucleate large RNA polymerase II clusters that grow and unfold before transcriptional activity disperses them. This work reveals how biophysical forces at enhancer surfaces dynamically build and dismantle stem cell transcription hubs, reshaping cell ...
Tim Klingberg +18 more
wiley +1 more source
Recruitment of Mediator Complex by Cell Type and Stage-Specific Factors Required for Tissue-Specific TAF Dependent Gene Activation in an Adult Stem Cell Lineage. [PDF]
PLoS Genetics, 2015 Onset of terminal differentiation in adult stem cell lineages is commonly marked by robust activation of new transcriptional programs required to make the appropriate differentiated cell type(s).
Chenggang Lu, Margaret T Fuller
doaj +1 more source
TDP‐43 Aggregation: The Healthy‐Toxic Balance of the Prion‐Like Domain
Advanced Science, EarlyView.TDP‐43 function relies on a delicate balance between reversible phase‐separated states and irreversible aggregation. Under physiological conditions, TDP‐43 forms dynamic droplets and oligomers that support normal cellular functions. In pathological contexts, this balance shifts toward aberrant aggregation, leading to toxic species.
Luca Zangrando +2 more
wiley +1 more source
Cell cycle and age-related modulations of mouse chromosome stiffness
eLifeChromosome structure is complex, and many aspects of chromosome organization are still not understood. Measuring the stiffness of chromosomes offers valuable insight into their structural properties.
Ning Liu +4 more
doaj +1 more source
The paternal genome and the health of the assisted reproductive technology child
Asian Journal of Andrology, 2015 As a number of children born by assisted reproductive technology (ART) are increasing each year across the developed world, the health of such offspring is a matter of public concern.
Sheena EM Lewis, Kishlay Kumar
doaj +1 more source
The Anatomical Record, EarlyView.Abstract Stenopodidea represents one of the basal lineages within Pleocyemata, yet the male reproductive system (MRS) of this group remains poorly understood, with limited information available regarding its morphology and function. This study provides the first detailed description of the MRS in four stenopodidean shrimp species from two families ...
Caio Santos Nogueira +2 more
wiley +1 more source
Progression of spermatocyte images through image analysis.
, 2019 On the left, cytological images of a pachytene spermatocyte from a castCAST × muscPWD F2 (top) and a domGI × domWSB F2 (bottom). Chromosome spreads stained for SYCP3 in red, MLH1 in green, and DAPI in blue. Scale bar = 10μm.
Bret A. Payseur (7310231) +3 more
core +1 more source
Ursolic Acid Alleviates Orchitis via Modulating Ferroptosis in Peritubular Myoid Cells of Testis
Animal Research and One Health, EarlyView.Ursolic acid modulates key ferroptosis‐related pathways in the peritubular myoid cells of the testis in forest musk deer. ABSTRACT Chronic stress adversely affects reproductive health, increasing susceptibility to pathologies such as orchitis. Additionally, the maintenance of iron homeostasis is essential for preserving the function of the testicles ...
Yang Wang +11 more
wiley +1 more source