Results 41 to 50 of about 17,497 (237)
Behavioral mechanisms of mammalian sperm guidance
Asian Journal of Andrology, 2015 In mammals, sperm guidance in the oviduct appears essential for successful sperm arrival at the oocyte. Hitherto, three different potential sperm guidance mechanisms have been recognized: thermotaxis, rheotaxis, and chemotaxis, each of them using ...
Serafín Pérez Cerezales +2 more
doaj +1 more source
Asian Journal of Andrology, 2015 One of the most common lesions present in the spermatozoa of human infertility patients is an idiopathic failure of sperm-egg recognition. Although this unique cellular interaction can now be readily by-passed by assisted reproductive strategies such as ...
Brett Nixon +5 more
doaj +1 more source
Fraksi Heksan Ekstrak Biji Pepaya Muda Dapat Menghambat Proses Spermatogenesis Mencit Jantan Lebih Besar Daripada Fraksi Metanol Ekstrak Biji Papaya Muda [PDF]
, 2008 Fraksi ekstrak heksan mengandung dua golongan zat aktif yang bersifat antifertilitas yaitu golongan steroid dan golongan triterpenoid yang diperkirakan bersifat antifertilitas, walupun mekanisme kerjanya belum jelas.
Satriyasa, B. K. (Bagus)
core
Chronic Hypoxia Disrupts Spermatogenesis Through ASXL2–EZH2–Mediated Microtubule Destabilization
Advanced Science, EarlyView.This study reveals the mechanism by which chronic hypoxia impairs spermatogenesis via the ASXL2–EZH2 axis, hindering the transition of spermatids from round to elongated forms. Key findings reveal that under hypoxic conditions, downregulated ASXL2 expression reduces EZH2 binding to the CEP162 promoter, leading to decreased H3K27me3 modification and ...
Jun Yin +11 more
wiley +1 more source
A comparative evaluation of semen parameters in pre- and post-Hurricane Katrina human population
Asian Journal of Andrology, 2015 A natural disaster leading to accumulation of environmental contaminants may have substantial effects on the male reproductive system. Our aim was to compare and assess semen parameters in a normospermic population residing in the Southern Louisiana, USA
Caner Baran +2 more
doaj +1 more source
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Varicocele and testicular function
Asian Journal of Andrology, 2015 Testicular varicocele, a dilation of the veins of the pampiniform plexus thought to increase testicular temperature via venous congestion, is commonly associated with male infertility.
Alexander W Pastuszak, Run Wang
doaj +1 more source
Recruitment of Mediator Complex by Cell Type and Stage-Specific Factors Required for Tissue-Specific TAF Dependent Gene Activation in an Adult Stem Cell Lineage. [PDF]
PLoS Genetics, 2015 Onset of terminal differentiation in adult stem cell lineages is commonly marked by robust activation of new transcriptional programs required to make the appropriate differentiated cell type(s).
Chenggang Lu, Margaret T Fuller
doaj +1 more source
Advanced Science, EarlyView.Cer24:1 levels are reduced in neutrophilic asthma and inversely correlate with disease severity and airway neutrophilia. Restoring Cer24:1 suppresses pathogenic Th17 differentiation by engaging EP2 on CD4+ T cells, thereby dampening the JAK2–STAT3–RORγt axis and reducing IL‐17 production.
Huan Liu +11 more
wiley +1 more source
Isolation of Sertoli, Leydig, and spermatogenic cells from the mouse testis
BioTechniques, 2011 A thorough understanding of the events during mammalian spermatogenesis requires studying specific molecular signatures of individual testicular cell populations as well as their interaction in co-cultures.
Yao-Fu Chang +4 more
doaj +1 more source