Results 21 to 30 of about 17,497 (237)

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

open access: yesAsian Journal of Andrology, 2015
Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus.
Kate L. Loveland   +5 more
doaj   +1 more source

Spermatocytic Tumor: A Review

open access: yesInternational Journal of Molecular Sciences, 2023
Spermatocytic tumor (ST) is a very rare disease, accounting for approximately 1% of testicular cancers. Previously classified as spermatocytic seminoma, it is currently classified within the non-germ neoplasia in-situ-derived tumors and has different clinical-pathologic features when compared with other forms of germ cell tumors (GCTs).
Simona Secondino   +8 more
openaire   +2 more sources

Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?

open access: yesAsian Journal of Andrology, 2015
This chapter explores the possibility that capacitation and apoptosis are linked processes joined by their common dependence on the continued generation of reactive oxygen species (ROS).
Robert J Aitken   +2 more
doaj   +1 more source

Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage

open access: yesAsian Journal of Andrology, 2015
Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Carol Coughlan   +7 more
doaj   +1 more source

Rbp4-Gal4, a germline driver that activates in meiosis, reveals functions for VCP in spermatid development

open access: yesFly, 2023
Valosin-containing protein (VCP) is a versatile and ubiquitously expressed AAA+ ATPase that regulates multiple stages of Drosophila spermatogenesis. While VCP has documented roles in mitotic spermatogonia and meiotic spermatocytes, it is also highly ...
Tyler J. Butsch   +2 more
doaj   +1 more source

Genetic and Chemical Controls of Sperm Fate and Spermatocyte Dedifferentiation via PUF-8 and MPK-1 in Caenorhabditis elegans

open access: yesCells, 2023
Using the nematode C. elegans germline as a model system, we previously reported that PUF-8 (a PUF RNA-binding protein) and LIP-1 (a dual-specificity phosphatase) repress sperm fate at 20 °C and the dedifferentiation of spermatocytes into mitotic cells ...
Youngyong Park   +5 more
doaj   +1 more source

Meiotic sex chromosome cohesion and autosomal synapsis are supported by Esco2.

open access: yes, 2020
In mitotic cells, establishment of sister chromatid cohesion requires acetylation of the cohesin subunit SMC3 (acSMC3) by ESCO1 and/or ESCO2. Meiotic cohesin plays additional but poorly understood roles in the formation of chromosome axial elements (AEs)
Biswas, U.   +6 more
core   +1 more source

Gonads and gametogenesis in Chaetodactylus osmiae (Acariformes: Astigmata: Chaetodactylidae) a parasite of solitary bees [PDF]

open access: yes, 2018
International audienceChaetodactylus osmiae (Dufour, 1839) is a mite parasitizing the solitary bee - Osmia rufa L.- used as a commercial pollinator. In this study we present the anatomy of female and male reproductive systems of this species as well as ...
Rożej-Pabijan, Elżbieta   +1 more
core   +3 more sources

Hormad1 mutation disrupts synaptonemal complex formation, recombination, and chromosome segregation in mammalian meiosis [PDF]

open access: yes, 2010
Meiosis is unique to germ cells and essential for reproduction. During the first meiotic division, homologous chromosomes pair, recombine, and form chiasmata.
Choi, Y   +8 more
core   +12 more sources

Human sperm chromatin epigenetic potential: genomics, proteomics, and male infertility

open access: yesAsian Journal of Andrology, 2015
The classical idea about the function of the mammalian sperm chromatin is that it serves to transmit a highly protected and transcriptionally inactive paternal genome, largely condensed by protamines, to the next generation.
Judit Castillo   +3 more
doaj   +1 more source

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