Results 21 to 30 of about 13,462 (242)
Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes [PDF]
In mammals, the testis-specific bromodomain and extra terminal (BET) protein BRDT is essential for spermatogenesis. In Drosophila, it was recently reported that the tBRD-1 protein is similarly required for male fertility.
Shuhei Kimura, Benjamin Loppin
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Biomarker-based sperm analysis elevates the treatment of human infertility and ameliorates reproductive performance in livestock. The negative biomarker-based approach focuses on proteins and ligands unique to defective spermatozoa, regardless of their ...
Peter Sutovsky +3 more
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Differing requirements for Augmin in male meiotic and mitotic spindle formation in Drosophila [PDF]
Animal cells divide using a microtubule-based, bipolar spindle. Both somatic, mitotic cells and sperm-producing male meiotic spermatocytes use centrosome-dependent and acentrosomal spindle-forming mechanisms.
Matthew S. Savoian, David M. Glover
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Spermatocytic Seminoma in the Rat [PDF]
During the necropsy of a 2-yr-old untreated control rat from a carcinogenicity study, a tan brown nodular mass was observed within the tunica albuginea of one testis. Both testes were processed for light and transmission electron microscopy. Histologically, the testicular mass was composed of round to polyhedral cells with distinct cell boundaries ...
S N, Kim +2 more
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Ezrin: a regulator of actin microfilaments in cell junctions of the rat testis
Ezrin, radixin, moesin and merlin (ERM) proteins are highly homologous actin-binding proteins that share extensive sequence similarity with each other.
N Ece Gungor-Ordueri +2 more
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Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus.
Kate L. Loveland +5 more
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Switch-like Behavior of Lysosomes and VCP Supports Spermatocyte Health and Development in Drosophila [PDF]
Changes to societal norms, such as the educational, marital, and child-bearing expectations have coincided with significant increases in infertility worldwide.
Butsch, Tyler James
core +1 more source
Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?
This chapter explores the possibility that capacitation and apoptosis are linked processes joined by their common dependence on the continued generation of reactive oxygen species (ROS).
Robert J Aitken +2 more
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Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage
Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Carol Coughlan +7 more
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Chromodomain Helicase DNA-Binding Proteins and Spermatogenesis: Current Advances. [PDF]
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Zhang M, Liu D, Liu G, Zhu M, Pan F.
europepmc +2 more sources

