Results 21 to 30 of about 13,462 (242)

Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes [PDF]

open access: yesOpen Biology, 2015
In mammals, the testis-specific bromodomain and extra terminal (BET) protein BRDT is essential for spermatogenesis. In Drosophila, it was recently reported that the tBRD-1 protein is similarly required for male fertility.
Shuhei Kimura, Benjamin Loppin
doaj   +1 more source

Negative biomarker based male fertility evaluation: Sperm phenotypes associated with molecular-level anomalies

open access: yesAsian Journal of Andrology, 2015
Biomarker-based sperm analysis elevates the treatment of human infertility and ameliorates reproductive performance in livestock. The negative biomarker-based approach focuses on proteins and ligands unique to defective spermatozoa, regardless of their ...
Peter Sutovsky   +3 more
doaj   +1 more source

Differing requirements for Augmin in male meiotic and mitotic spindle formation in Drosophila [PDF]

open access: yesOpen Biology, 2014
Animal cells divide using a microtubule-based, bipolar spindle. Both somatic, mitotic cells and sperm-producing male meiotic spermatocytes use centrosome-dependent and acentrosomal spindle-forming mechanisms.
Matthew S. Savoian, David M. Glover
doaj   +1 more source

Spermatocytic Seminoma in the Rat [PDF]

open access: yesToxicologic Pathology, 1985
During the necropsy of a 2-yr-old untreated control rat from a carcinogenicity study, a tan brown nodular mass was observed within the tunica albuginea of one testis. Both testes were processed for light and transmission electron microscopy. Histologically, the testicular mass was composed of round to polyhedral cells with distinct cell boundaries ...
S N, Kim   +2 more
openaire   +2 more sources

Ezrin: a regulator of actin microfilaments in cell junctions of the rat testis

open access: yesAsian Journal of Andrology, 2015
Ezrin, radixin, moesin and merlin (ERM) proteins are highly homologous actin-binding proteins that share extensive sequence similarity with each other.
N Ece Gungor-Ordueri   +2 more
doaj   +1 more source

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

open access: yesAsian Journal of Andrology, 2015
Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus.
Kate L. Loveland   +5 more
doaj   +1 more source

Switch-like Behavior of Lysosomes and VCP Supports Spermatocyte Health and Development in Drosophila [PDF]

open access: yes, 2023
Changes to societal norms, such as the educational, marital, and child-bearing expectations have coincided with significant increases in infertility worldwide.
Butsch, Tyler James
core   +1 more source

Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?

open access: yesAsian Journal of Andrology, 2015
This chapter explores the possibility that capacitation and apoptosis are linked processes joined by their common dependence on the continued generation of reactive oxygen species (ROS).
Robert J Aitken   +2 more
doaj   +1 more source

Sperm DNA fragmentation, recurrent implantation failure and recurrent miscarriage

open access: yesAsian Journal of Andrology, 2015
Evidence is increasing that the integrity of sperm DNA may also be related to implantation failure and recurrent miscarriage (RM). To investigate this, the sperm DNA fragmentation in partners of 35 women with recurrent implantation failure (RIF ...
Carol Coughlan   +7 more
doaj   +1 more source

Chromodomain Helicase DNA-Binding Proteins and Spermatogenesis: Current Advances. [PDF]

open access: yesAndrology
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Zhang M, Liu D, Liu G, Zhu M, Pan F.
europepmc   +2 more sources

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