Results 1 to 10 of about 11,212 (162)

The forbidden doubling: exploring rare spermatocyte polyploidy in mammals [PDF]

Comparative Cytogenetics
We first studied several rare cases of over-diploid spermatocyte emergence using advanced immunocytochemical methods and a cross-species approach in subterranean rodents Ellobius tancrei (Blasius, 1884), E. alaicus Vorontsov et al., 1969, E.
Sergey Matveevsky, Oxana Kolomiets, Tatiana Grishaeva, Aleksey Bogdanov, Valentina Tambovtseva, Irina Bakloushinskaya   +5 more
doaj   +4 more sources

Wdr17 Regulates Cell Proliferation, Cell Cycle Progression and Apoptosis in Mouse Spermatocyte Cell Line

Animals
We identified Wdr17 as a highly expressed gene in pachytene spermatocytes by transcriptomic analysis of mouse testis. Germ cell-deficient infertile mouse models had significantly reduced Wdr17 expression. We performed gene interference and overexpression
Huaqiang Yang, Zicong Li, Zhenfang Wu
exaly   +3 more sources

Cadmium induces ferroptosis in mouse spermatocytes by activating the ROS–TCA pathway [PDF]

Scientific Reports
Cadmium (Cd) can cause testis toxicity, and we have demonstrated Cd induced ferroptosis in testis. However, the underlying toxic mechanism has not yet been fully elucidated. Here, we performed in vitro experiments on a mouse spermatocyte cell line.
Lijuan Xiong, Lijun Yi, Xingying Zeng, Jiyi Huang, Hong Liu, Hong Li   +5 more
doaj   +2 more sources

Spermatocyte injection into meiotic oocytes rescues diplotene, but not pachytene, arrest in azoospermic mutant mice [PDF]

Human Reproduction Open
Yuki Osawa, Masahito Ikawa, Kimiko Inoue   +2 more
exaly   +2 more sources

The Application of Single-Cell RNA Sequencing in Mammalian Meiosis Studies

Frontiers in Cell and Developmental Biology, 2021
Meiosis is a cellular division process that produces gametes for sexual reproduction. Disruption of complex events throughout meiosis, such as synapsis and homologous recombination, can lead to infertility and aneuploidy.
Yiheng Peng, Huanyu Qiao
doaj   +1 more source

Identification of fish spermatogenic cells through high-throughput immunofluorescence against testis with an antibody set

Frontiers in Endocrinology, 2023
Image-based identification and quantification of different types of spermatogenic cells is of great importance, not only for reproductive studies but also for genetic breeding.
Ding Ye, Tao Liu, Yongming Li, Yaping Wang, Wei Hu, Zuoyan Zhu, Yonghua Sun   +6 more
doaj   +1 more source

Hypoxia causes seminiferous tubule damage by inducing apoptosis of spermatocytes in mice

Di-san junyi daxue xuebao, 2020
Objective To investigate the damage of seminiferous tubules in mice exposed to hypoxia and the effects of hypoxia on apoptosis of mouse spermatocytes in the seminiferous tubules.
YIN Jun, LIU Junze, NI Bing, TANG Zhongwei, GAO Zhiqi, ZHAO Li, ZHANG Mengjie, CHEN Dewei, HE Wenjuan, LIAO Weigong   +9 more
doaj   +1 more source

Rbp4-Gal4, a germline driver that activates in meiosis, reveals functions for VCP in spermatid development

Fly, 2023
Valosin-containing protein (VCP) is a versatile and ubiquitously expressed AAA+ ATPase that regulates multiple stages of Drosophila spermatogenesis. While VCP has documented roles in mitotic spermatogonia and meiotic spermatocytes, it is also highly ...
Tyler J. Butsch, Alyssa E. Johnson, K. Adam Bohnert   +2 more
doaj   +1 more source

Two bromodomain proteins functionally interact to recapitulate an essential BRDT-like function in Drosophila spermatocytes [PDF]

Open Biology, 2015
In mammals, the testis-specific bromodomain and extra terminal (BET) protein BRDT is essential for spermatogenesis. In Drosophila, it was recently reported that the tBRD-1 protein is similarly required for male fertility.
Shuhei Kimura, Benjamin Loppin
doaj   +1 more source

Differing requirements for Augmin in male meiotic and mitotic spindle formation in Drosophila [PDF]

Open Biology, 2014
Animal cells divide using a microtubule-based, bipolar spindle. Both somatic, mitotic cells and sperm-producing male meiotic spermatocytes use centrosome-dependent and acentrosomal spindle-forming mechanisms.
Matthew S. Savoian, David M. Glover
doaj   +1 more source