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The forbidden doubling: exploring rare spermatocyte polyploidy in mammals [PDF]
Comparative CytogeneticsWe first studied several rare cases of over-diploid spermatocyte emergence using advanced immunocytochemical methods and a cross-species approach in subterranean rodents Ellobius tancrei (Blasius, 1884), E. alaicus Vorontsov et al., 1969, E.
Sergey Matveevsky +5 more
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AnimalsWe identified Wdr17 as a highly expressed gene in pachytene spermatocytes by transcriptomic analysis of mouse testis. Germ cell-deficient infertile mouse models had significantly reduced Wdr17 expression. We performed gene interference and overexpression
Hua-Qiang Yang, Xianyu Zhang
exaly +3 more sources
Cadmium induces ferroptosis in mouse spermatocytes by activating the ROS–TCA pathway [PDF]
Scientific ReportsCadmium (Cd) can cause testis toxicity, and we have demonstrated Cd induced ferroptosis in testis. However, the underlying toxic mechanism has not yet been fully elucidated. Here, we performed in vitro experiments on a mouse spermatocyte cell line.
Lijuan Xiong +5 more
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The Application of Single-Cell RNA Sequencing in Mammalian Meiosis Studies
Frontiers in Cell and Developmental Biology, 2021 Meiosis is a cellular division process that produces gametes for sexual reproduction. Disruption of complex events throughout meiosis, such as synapsis and homologous recombination, can lead to infertility and aneuploidy.
Yiheng Peng, Huanyu Qiao
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Frontiers in Endocrinology, 2023 Image-based identification and quantification of different types of spermatogenic cells is of great importance, not only for reproductive studies but also for genetic breeding.
Ding Ye +6 more
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Sexual Dimorphism in Mouse Meiosis
Frontiers in Cell and Developmental Biology, 2021 Meiosis is a highly conserved and essential process in gametogenesis in sexually reproducing organisms. However, there are substantial sex-specific differences within individual species with respect to meiosis-related chromatin reorganization ...
Rong Hua, Mingxi Liu
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Hypoxia causes seminiferous tubule damage by inducing apoptosis of spermatocytes in mice
Di-san junyi daxue xuebao, 2020 Objective To investigate the damage of seminiferous tubules in mice exposed to hypoxia and the effects of hypoxia on apoptosis of mouse spermatocytes in the seminiferous tubules.
YIN Jun +9 more
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Archives of Pathology & Laboratory Medicine, 2009 Abstract Spermatocytic seminoma is a rare germ cell tumor distinct from classical seminoma, both clinically and pathologically. It affects older men, has not been associated with a history of cryptorchidism, and has no known counterpart in ovary or any other site.
Nidhi, Aggarwal, Anil V, Parwani
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Exploring the role of mononuclear phagocytes in the epididymis
Asian Journal of Andrology, 2015 The onslaught of foreign antigens carried by spermatozoa into the epididymis, an organ that has not demonstrated immune privilege, a decade or more after the establishment of central immune tolerance presents a unique biological challenge.
Nicolas Da Silva, Tegan B Smith
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Asian Journal of Andrology, 2015 Biomarker-based sperm analysis elevates the treatment of human infertility and ameliorates reproductive performance in livestock. The negative biomarker-based approach focuses on proteins and ligands unique to defective spermatozoa, regardless of their ...
Peter Sutovsky +3 more
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