Results 11 to 20 of about 11,282 (214)
The forbidden doubling: exploring rare spermatocyte polyploidy in mammals [PDF]
We first studied several rare cases of over-diploid spermatocyte emergence using advanced immunocytochemical methods and a cross-species approach in subterranean rodents Ellobius tancrei (Blasius, 1884), E. alaicus Vorontsov et al., 1969, E.
Sergey Matveevsky +5 more
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We identified Wdr17 as a highly expressed gene in pachytene spermatocytes by transcriptomic analysis of mouse testis. Germ cell-deficient infertile mouse models had significantly reduced Wdr17 expression. We performed gene interference and overexpression
Huaqiang Yang +2 more
exaly +3 more sources
Cadmium induces ferroptosis in mouse spermatocytes by activating the ROS–TCA pathway [PDF]
Cadmium (Cd) can cause testis toxicity, and we have demonstrated Cd induced ferroptosis in testis. However, the underlying toxic mechanism has not yet been fully elucidated. Here, we performed in vitro experiments on a mouse spermatocyte cell line.
Lijuan Xiong +5 more
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The Application of Single-Cell RNA Sequencing in Mammalian Meiosis Studies
Meiosis is a cellular division process that produces gametes for sexual reproduction. Disruption of complex events throughout meiosis, such as synapsis and homologous recombination, can lead to infertility and aneuploidy.
Yiheng Peng, Huanyu Qiao
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Image-based identification and quantification of different types of spermatogenic cells is of great importance, not only for reproductive studies but also for genetic breeding.
Ding Ye +6 more
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Sexual Dimorphism in Mouse Meiosis
Meiosis is a highly conserved and essential process in gametogenesis in sexually reproducing organisms. However, there are substantial sex-specific differences within individual species with respect to meiosis-related chromatin reorganization ...
Rong Hua, Mingxi Liu
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Hypoxia causes seminiferous tubule damage by inducing apoptosis of spermatocytes in mice
Objective To investigate the damage of seminiferous tubules in mice exposed to hypoxia and the effects of hypoxia on apoptosis of mouse spermatocytes in the seminiferous tubules.
YIN Jun +9 more
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Spermatocytic tumor (ST) is a very rare disease, accounting for approximately 1% of testicular cancers. Previously classified as spermatocytic seminoma, it is currently classified within the non-germ neoplasia in-situ-derived tumors and has different clinical-pathologic features when compared with other forms of germ cell tumors (GCTs).
Simona Secondino +8 more
openaire +2 more sources
Valosin-containing protein (VCP) is a versatile and ubiquitously expressed AAA+ ATPase that regulates multiple stages of Drosophila spermatogenesis. While VCP has documented roles in mitotic spermatogonia and meiotic spermatocytes, it is also highly ...
Tyler J. Butsch +2 more
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Abstract Spermatocytic seminoma is a rare germ cell tumor distinct from classical seminoma, both clinically and pathologically. It affects older men, has not been associated with a history of cryptorchidism, and has no known counterpart in ovary or any other site.
Nidhi, Aggarwal, Anil V, Parwani
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