Unique properties of Drosophila spermatocyte primary cilia
Biology Open, 2013 Summary The primary cilium is an essential organelle required for animal development and adult homeostasis that is found on most animal cells. The primary cilium contains a microtubule-based axoneme cytoskeleton that typically grows from the mother ...
Maria Giovanna Riparbelli +3 more
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Cells, 2023 Using the nematode C. elegans germline as a model system, we previously reported that PUF-8 (a PUF RNA-binding protein) and LIP-1 (a dual-specificity phosphatase) repress sperm fate at 20 °C and the dedifferentiation of spermatocytes into mitotic cells ...
Youngyong Park +5 more
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VCP promotes tTAF-target gene expression and spermatocyte differentiation by downregulating mono-ubiquitylated H2A [PDF]
, 2023 Valosin-containing protein (VCP) binds and extracts ubiquitylated cargo to regulate protein homeostasis. VCP has been studied primarily in aging and disease contexts, but it also affects germline development.
Butsch, Tyler J. +3 more
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Chromosome territories in control spermatocyte.
, 2022 A single spermatocyte during late S5 is displayed after time-lapse imaging of a spermatocyte cyst expressing Cenp-A/Cid-EGFP (green) and His2Av-mRFP (magenta).
Christian F. Lehner (9449522) +1 more
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Overview of the Drosophila primary spermatocyte nucleus.
, 2023 (A) Confocal image of Drosophila primary spermatocyte nucleus immuno-labelled with pan-histone antibody labelling core histones plus H1. (B) Schematic showing the characteristic features of the Drosophila primary spermatocyte nuclei.
Leila Muresan (167566) +5 more
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Doxorubicin and 4-Hydroperoxycyclophosphamide Alter Mitochondrial Dynamics and miR-34 Expression in Spermatogonia and Spermatocytes In Vitro. [PDF]
Basic Clin Pharmacol ToxicolABSTRACT Doxorubicin (DOX) and cyclophosphamide (CP) are widely used chemotherapeutic agents with known gonadotoxic effects. Since miRNAs play a key role in the transcriptional regulation of spermatogenesis, they are suggested as biomarkers for male infertility.
Öztatlıcı H +4 more
europepmc +2 more sources
Spermatocyte injection into meiotic oocytes rescues diplotene, but not pachytene, arrest in azoospermic mutant mice. [PDF]
Hum Reprod OpenSTUDY QUESTION At which arrest stage can spermatocytes be rescued by injection into meiotic oocytes? SUMMARY ANSWER In mice, spermatocytes arrested at the diplotene stage, but not at the pachytene stage, can resume meiosis within immature oocytes and ...
Ogonuki N +15 more
europepmc +2 more sources
Exploring the role of mononuclear phagocytes in the epididymis
Asian Journal of Andrology, 2015 The onslaught of foreign antigens carried by spermatozoa into the epididymis, an organ that has not demonstrated immune privilege, a decade or more after the establishment of central immune tolerance presents a unique biological challenge.
Nicolas Da Silva, Tegan B Smith
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Protective Effects of Lactobacillus-Derived Probiotics and Postbiotics on Renal and Reproductive Function in Escherichia coli-Infected Rats. [PDF]
Vet Med SciA Lactobacillus‐derived probiotic and postbiotic mixture alleviates E. coli–induced renal and reproductive dysfunction by modulating oxidative stress, inflammatory responses, and apoptosis, leading to improved tissue integrity and sperm quality. ABSTRACT Background Escherichia coli infections of the genitourinary tract are a major cause of renal and ...
Sedghi S, Keshtmand Z, Hosseini S.
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Progression through M I in control spermatocyte.
, 2021 Spermatocytes expressing Cenp-A/Cid-EGFP and His2Av-mRFP were analyzed by time-lapse imaging at 45 sec intervals. Progression through M I, as observed in the spermatocyte presented in Fig 4A, is shown in a maximum intensity projection.
Christian F. Lehner (9449522) +1 more
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