Results 61 to 70 of about 32,786 (330)

Cell cycle and age-related modulations of mouse chromosome stiffness

eLife
Chromosome structure is complex, and many aspects of chromosome organization are still not understood. Measuring the stiffness of chromosomes offers valuable insight into their structural properties.
Ning Liu, Wenan Qiang, Philip W Jordan, John F Marko, Huanyu Qiao   +4 more
doaj   +1 more source

Ezrin: a regulator of actin microfilaments in cell junctions of the rat testis

Asian Journal of Andrology, 2015
Ezrin, radixin, moesin and merlin (ERM) proteins are highly homologous actin-binding proteins that share extensive sequence similarity with each other.
N Ece Gungor-Ordueri, Ciler Celik-Ozenci, C Yan Cheng   +2 more
doaj   +1 more source

Transcriptional Inhibition of lncRNA gadd7 by CRISPR/dCas9-KRAB Protects Spermatocyte Viability

Frontiers in Molecular Biosciences, 2021
Our previous study found that lncRNA gadd7 was up-regulated in the semen of varicocele patients, and could promote the apoptosis of mouse spermatocytes and inhibit their proliferation.
Jun Zhao, Wenmin Ma, Yucheng Zhong, Hao Deng, Bingyu Zhou, Yaqin Wu, Meiqiong Yang, Huan Li   +7 more
doaj   +1 more source

Defects in Meiotic Recombination Delay Progression Through Pachytene in Tex19.1-/- Mouse Spermatocytes [PDF]

, 2018
Recombination, synapsis, chromosome segregation and gene expression are co-ordinately regulated during meiosis to ensure successful execution of this specialised cell division.
A Chicheportiche, A Copsey, AH Peters, AM Lyndaker, B Drabent, CA Adelman, CK Cahoon, David Read, E Bolcun-Filas, E Meijering, E Testa, EA Ahmed, EF Joyce, F Baudat, F Baudat, F Carofiglio, F Yang, H Nakata, HBDP Rao, I Roig, Ian R. Adams, J Chen, J Cobb, J Reichmann, J Reichmann, J Schindelin, JA Hackett, James H. Crichton, JH Crichton, JH Crichton, JH Lammers, JM Cloutier, JMA Turner, JY An, K Daniel, L Kauppi, L Kauppi, L Wojtasz, L Wojtasz, L Xu, L-Y Lu, LH Hartwell, LK Anderson, M Barchi, M Faieta, M Fujimuro, M MacLennan, M Marcet-Ortega, N Reynolds, NM Vranis, PB Moens, PJ Romanienko, PJ Wang, PM Carlton, PS Burgoyne, R Core Team, R Öllinger, RL Meuwissen, S Kuntz, S Pacheco, S Schoenmakers, SK Mahadevaiah, SK Mahadevaiah, TJ Broering, VD Rinaldi, VV Subramanian, WM Baarends, XC Li, Y Costa, Y Tarabay, Y-H Shin, YT Kwon   +71 more
core   +1 more source

Comparative Single‐Cell Transcriptomic Atlas Reveals the Genetic Regulation of Reproductive Traits

Advanced Science, EarlyView.
A cross‐species single‐cell transcriptomic atlas of reproductive and central nervous system tissues from sheep and humans reveals conserved cellular programs and regulatory networks that regulated fertility. Integration with GWAS for sheep lifetime average litter size identifies UNC5–SLIT–BMP signaling as a core pathway coordinating neuroendocrine ...
Bingru Zhao, Hanpeng Luo, Dailu Guan, Xuefeng Fu, Feng Wang, Guoming Zhang, Shanglai Li, Hua Yang, Yanli Zhang   +8 more
wiley   +1 more source

Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis

Asian Journal of Andrology, 2015
Importin proteins were originally characterized for their central role in protein transport through the nuclear pores, the only intracellular entry to the nucleus.
Kate L. Loveland, Andrew T. Major, Romaly Butler, Julia C. Young, David A. Jans, Yoichi Miyamoto   +5 more
doaj   +1 more source

Mechanisms of Aristolochic Acid Resistance in Specialist Butterflies and Evolutionary Insights for Potential Protective Pathways

Advanced Science, EarlyView.
The study provides an extreme example of insect adaptation to highly toxic defenses of host plants, and investigates the complex strategies to resist carcinogenic aristolochic acids, including physical isolation, metabolic detoxification, and DNA repair.
Yang Luan, Yubo Zhang, Jingjing Li, Jianqing Zhu, Yuyang Lei, Yushi Hu, Zhenqiang Xin, Tianpei Xie, Jiang Zheng, Yuanyuan Lin, Jingjing Shen, Yiyi Cao, Xinyue You, Jing Xi, Jiaying Wu, Weiying Liu, Xinyu Zhang, Yuanting Zheng, David J. Lohman, Leming Shi, Wei Zhang   +20 more
wiley   +1 more source

The impact of hydroalcoholic extracts of Peganum harmala and Piper longum on pituitary- gonad axis hormone levels of male NMRI mice

یافته‌های نوین در علوم زیستی, 2017
Several therapeutic effects have been reported for Peganum harmala and Piper longum. These plants contain flavonoids that probably can affect reproductive endocrine system and reduce fertility.
Namdar Yousefvand, Delaram Eslimi Esfahani, Tayebeh Bahrami   +2 more
doaj  

Wdr17 Regulates Cell Proliferation, Cell Cycle Progression and Apoptosis in Mouse Spermatocyte Cell Line

Animals
We identified Wdr17 as a highly expressed gene in pachytene spermatocytes by transcriptomic analysis of mouse testis. Germ cell-deficient infertile mouse models had significantly reduced Wdr17 expression. We performed gene interference and overexpression
Xin Zhao, Taili Jin, Xi Ji, Qiuyan Zhang, Xianyu Zhang, Zhenfang Wu, Zicong Li, Huaqiang Yang   +7 more
doaj   +1 more source

Are sperm capacitation and apoptosis the opposite ends of a continuum driven by oxidative stress?

Asian Journal of Andrology, 2015
This chapter explores the possibility that capacitation and apoptosis are linked processes joined by their common dependence on the continued generation of reactive oxygen species (ROS).
Robert J Aitken, Mark A Baker, Brett Nixon   +2 more
doaj   +1 more source