Results 41 to 50 of about 26,767 (249)
Spermatocytes of Igsf11 deficient mouse are arrested at diplotene.
(A-C) Comparison of the synaptonemal complex assembly (A and B) and DSBs repair (C) in spermatocytes of the control (Igsf11+/-) and mutant (Igsf11-/-) mice using SYCP3, SYCP1, and γH2AX as markers. Representative confocal images of diplotene stage Igsf11
Gengzhen Zhu (10066444) +8 more
core +1 more source
Dynamic sex chromosome expression in Drosophila male germ cells
Sex chromosome gene content and expression is unusual. Here the authors use single cell RNA-Seq on Drosophila larvae to demonstrate that the single X and pair of 4th chromosomes are specifically inactivated in primary spermatocytes, while genes on the ...
Sharvani Mahadevaraju +22 more
doaj +1 more source
Haploid male gametes are produced through meiosis during gametogenesis. Whereas the cell biology of mitosis and meiosis is well studied in the nematode Caenorhabditis elegans, comparatively little is known regarding the physical division of primary ...
Wang, Xiangchuan +5 more
core +1 more source
The purpose of this study was to evaluate the consequences of bisphenol A (BPA) exposure in zebrafish (Danio rerio). Short-term effects at a testes level were assessed by means of different biomarkers in 60 male zebrafish exposed for 14 days in aquariums
A.J. Lora +5 more
doaj +1 more source
The spermatocytic seminoma: views on pathogenesis [PDF]
The spermatocytic seminoma has clinical and histological characteristics which differ from those of other germ cell tumours of the testis. Classical seminomas and teratomas are believed to originate from intratubular carcinoma‐in‐situ (CIS), which is almost invariably found adjacent to these neoplasms. In addition, DNA analysis of these tumours and the
J, Müller +2 more
openaire +2 more sources
Meiotic arrest due to loss of Med22 function in spermatocytes.
(A, B) Phase contrast images of testes from (A) wild type and (B) Med22RNAi (Bam-Gal4;UAS-Med22RNAi) flies. Bar: 100 μm. (C-H’) representative (C-H) phase contrast and (C’-H’) Hoechst stain images of (C-C’) wild type mature spermatocytes, (D-D’) upper ...
Chenggang Lu (2203288) +1 more
core +1 more source
The germline genome serves as a crucial battleground for transposon expansion, as transposons can increase their copy numbers in offspring when activated within germ cells.
Yuange Duan, Qiuhua Xie, Ling Ma, Qi Cao
doaj +1 more source
Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein
The cellular prion protein PrPC is highly expressed in neurons, but also present in non-neuronal tissues, including the testicles and spermatozoa. Most immune cells and their bone marrow precursors also express PrPC.
Malin R. Reiten +17 more
doaj +1 more source
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu +23 more
wiley +1 more source
Centromere pairing is absent in Sycp1 knockout spermatocytes.
Surface chromosome spreads of pachytene (A, B) and diplotene (C–H) wild-type and Sycp1 knockout spermatocytes. Note that centromeres (red) in Sycp1 knockout spermatocytes are in close proximity but are not paired.
Harry Scherthan (155128) +6 more
core +1 more source

