Results 41 to 50 of about 26,767 (249)

Spermatocytes of Igsf11 deficient mouse are arrested at diplotene.

open access: yes, 2021
(A-C) Comparison of the synaptonemal complex assembly (A and B) and DSBs repair (C) in spermatocytes of the control (Igsf11+/-) and mutant (Igsf11-/-) mice using SYCP3, SYCP1, and γH2AX as markers. Representative confocal images of diplotene stage Igsf11
Gengzhen Zhu (10066444)   +8 more
core   +1 more source

Dynamic sex chromosome expression in Drosophila male germ cells

open access: yesNature Communications, 2021
Sex chromosome gene content and expression is unusual. Here the authors use single cell RNA-Seq on Drosophila larvae to demonstrate that the single X and pair of 4th chromosomes are specifically inactivated in primary spermatocytes, while genes on the ...
Sharvani Mahadevaraju   +22 more
doaj   +1 more source

Cortical recruitment of centralspindlin and rhoa effectors during meiosis i of caenorhabditis elegans primary spermatocytes

open access: yes, 2021
Haploid male gametes are produced through meiosis during gametogenesis. Whereas the cell biology of mitosis and meiosis is well studied in the nematode Caenorhabditis elegans, comparatively little is known regarding the physical division of primary ...
Wang, Xiangchuan   +5 more
core   +1 more source

Adverse effects of bisphenol A on the testicular parenchyma of zebrafish revealed using histomorphological methods

open access: yesVeterinární Medicína, 2016
The purpose of this study was to evaluate the consequences of bisphenol A (BPA) exposure in zebrafish (Danio rerio). Short-term effects at a testes level were assessed by means of different biomarkers in 60 male zebrafish exposed for 14 days in aquariums
A.J. Lora   +5 more
doaj   +1 more source

The spermatocytic seminoma: views on pathogenesis [PDF]

open access: yesInternational Journal of Andrology, 1987
The spermatocytic seminoma has clinical and histological characteristics which differ from those of other germ cell tumours of the testis. Classical seminomas and teratomas are believed to originate from intratubular carcinoma‐in‐situ (CIS), which is almost invariably found adjacent to these neoplasms. In addition, DNA analysis of these tumours and the
J, Müller   +2 more
openaire   +2 more sources

Meiotic arrest due to loss of Med22 function in spermatocytes.

open access: yes, 2016
(A, B) Phase contrast images of testes from (A) wild type and (B) Med22RNAi (Bam-Gal4;UAS-Med22RNAi) flies. Bar: 100 μm. (C-H’) representative (C-H) phase contrast and (C’-H’) Hoechst stain images of (C-C’) wild type mature spermatocytes, (D-D’) upper ...
Chenggang Lu (2203288)   +1 more
core   +1 more source

Abundant A-to-I RNA editing in spermatocytes may suppress transposons to compensate for piRNA downregulation in male germlines

open access: yesRNA Biology
The germline genome serves as a crucial battleground for transposon expansion, as transposons can increase their copy numbers in offspring when activated within germ cells.
Yuange Duan, Qiuhua Xie, Ling Ma, Qi Cao
doaj   +1 more source

Stress Resilience of Spermatozoa and Blood Mononuclear Cells without Prion Protein

open access: yesFrontiers in Molecular Biosciences, 2018
The cellular prion protein PrPC is highly expressed in neurons, but also present in non-neuronal tissues, including the testicles and spermatozoa. Most immune cells and their bone marrow precursors also express PrPC.
Malin R. Reiten   +17 more
doaj   +1 more source

Grtp1 Safeguards Against Paternal Reproductive Aging and Intergenerational Behavioral Deficits by Preserving Redox Homeostasis

open access: yesAdvanced Science, EarlyView.
This study identifies that Grtp1 maintains germline redox homeostasis by interacting with PRDX1/4‐TXN to antagonize paternal reproductive aging. Growth hormone restores Grtp1 expression, rectifies aberrant sperm DNA methylation, and ameliorates intergenerational anxiety and social deficits, highlighting the GH‐GRTP1 axis as a promising intervention ...
Yingdong Liu   +23 more
wiley   +1 more source

Centromere pairing is absent in Sycp1 knockout spermatocytes.

open access: yes, 2012
Surface chromosome spreads of pachytene (A, B) and diplotene (C–H) wild-type and Sycp1 knockout spermatocytes. Note that centromeres (red) in Sycp1 knockout spermatocytes are in close proximity but are not paired.
Harry Scherthan (155128)   +6 more
core   +1 more source

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