Results 111 to 120 of about 168,606 (377)

Fraksi Heksan Ekstrak Biji Pepaya Muda Dapat Menghambat Proses Spermatogenesis Mencit Jantan Lebih Besar Daripada Fraksi Metanol Ekstrak Biji Papaya Muda [PDF]

open access: yes, 2008
Fraksi ekstrak heksan mengandung dua golongan zat aktif yang bersifat antifertilitas yaitu golongan steroid dan golongan triterpenoid yang diperkirakan bersifat antifertilitas, walupun mekanisme kerjanya belum jelas.
Satriyasa, B. K. (Bagus)
core  

Ethnomedicinal Uses, Phytochemistry, Pharmacological Activities, and Toxicology of the Subfamily Gomphrenoideae (Amaranthaceae): A Comprehensive Review

open access: yesChemistry &Biodiversity, EarlyView.
ABSTRACT The subfamily Gomphrenoideae is composed of about 480 accepted species, many of which have been historically used as medicinal plants, reason why they have been studied in terms of chemical profile, biological activity, and safety. This review consolidates the advances in research on this subfamily over the past 47 years, emphasizing its ...
Dayanna Isabel Araque Gelves   +3 more
wiley   +1 more source

DNMT3A-dependent DNA methylation is required for spermatogonial stem cells to commit to spermatogenesis

open access: yesNature Genetics, 2022
Mathilde Dura   +11 more
semanticscholar   +1 more source

The lottery of spermatogenesis [PDF]

open access: yes, 2019
AbstractThe causes of male infertility are yet to be fully understood. Here, we propose that male infertility can be partly attributed to the insufficiency of cytoplasmically-inherited proteins in sperms. Using a simple stochastic model of spermatogenesis, we show that in a range of parameters, the proportion of viable sperms can be reduced simply due ...
Kalirad, Ata   +2 more
openaire   +1 more source

Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage

open access: yesChemistry &Biodiversity, EarlyView.
Graphical abstract of Bee‐Derived Antioxidants as a Protective Strategy Against Doxorubicin‐Induced Ovarian Damage ABSTRACT Antineoplastic agents can induce tissue damage through oxidative stress mechanisms. Doxorubicin, a widely used chemotherapeutic agent, has been shown to cause permanent damage to reproductive tissues.
Meltem Arıkan Malkoc   +3 more
wiley   +1 more source

Testicular miRNAs in relation to spermatogenesis, spermatogonial stem cells and cancer/testis genes

open access: yesScientific African, 2019
The process of spermatogenesis in human involves three organized biological processes, through which spermatogonia cells undergo mitosis, meiosis and finally differentiation into mature spermatozoa.
Maryam Beigom Mobasheri   +1 more
doaj  

Multi-omics analysis reveals that iron deficiency impairs spermatogenesis by gut-hormone synthesis axis

open access: yesEcotoxicology and Environmental Safety, 2022
Considering that research has mainly focussed on how excessive iron supplementation leads to reproductive cytotoxicity, there is a lack of in-depth research on reproductive system disorders caused by iron deficiency. To gain a better understanding of the
Fa-Li Zhang   +6 more
doaj  

TRiC Is a Structural Component of Mammalian Sperm Axonemes

open access: yesCytoskeleton, EarlyView.
ABSTRACT The TRiC chaperonin is responsible for folding ~5%–10% of the proteome in eukaryotic cells. Our recent cryo‐electron microscopy studies of axonemes from diverse mammalian cell types led to the surprising discovery that a fully assembled TRiC chaperonin is a structural component of mammalian sperm flagella, where it is tethered to the radial ...
Alan Brown   +3 more
wiley   +1 more source

Single Cell Map of Human Azoospermia Testis Caused by Cyclophosphamide Chemotherapy

open access: yesScientific Data
Chemotherapeutic drugs will affect the process of spermatogenesis. However, most current studies on the effects of chemotherapeutic drugs on spermatogenesis are based on mouse models, with a shortage of human body evidence.
Jian Cao   +7 more
doaj   +1 more source

Endocrine control of spermatogenesis in the ram.

open access: yesJournal of reproduction and fertility. Supplement, 2019
In the ram, the size of the testes is related to the concentrations of FSH, LH and testosterone in the blood. A significant linear relationship is observed between testicular size and the level of FSH until a maximum after which no further increase in ...
M. Courot, R. Ortavant
semanticscholar   +1 more source

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