Results 241 to 250 of about 66,364 (295)

Durable Response to Pazopanib (Tyrosine Kinase Inhibitor) in a Patient With EWSR1::CREM Gene Fusion Positive Intra‐Abdominal Unclassified Epithelioid Sarcoma

Genes, Chromosomes and Cancer, Volume 64, Issue 10, October 2025.
ABSTRACT EWSR1::CREM fusion positive intrabdominal sarcomas defines a rare emerging group of aggressive mesenchymal neoplasms with a predilection for the celomic cavity and often manifesting perplexing immunophenotypic profile. There is no specific standard of care therapeutic option though anecdotal reports response to pazopanib have been reported. We
Saba Shafi, Dan Jones, Xiaokang Pan, Marium Husain, Alan Rogers, Steve Oghumu, O. Hans Iwenofu   +6 more
wiley   +1 more source

<i>Rnf32</i> is not essential for spermatogenesis and male fertility in mice. [PDF]

PeerJ
Kong H, Yin Y, Zeng N, Zhu Y, Cui Y.
europepmc   +1 more source

Direct Development of Golf Ball Sponges, Genus Craniella (Demospongiae, Tetractinellida) From the Northeast Atlantic Ocean

Molecular Reproduction and Development, Volume 92, Issue 10, October 2025.
ABSTRACT Among the eight types of development in sponges, the least common and least studied is direct, non‐larval development during viviparity. To supplement our knowledge of this rare type of demosponge development, we present here a description of the embryonic development of four species of the genus Craniella (Demospongiae, order Tetractinellida)
Paco Cárdenas, Sandrine Chenesseau, Jim Drewery, Alexander Ereskovsky   +3 more
wiley   +1 more source

Dynamics of recombination, X inactivation and centromere proteins during stick insect spermatogenesis. [PDF]

PLoS Genet
Dumas Z, Toubiana W, Delattre M, Schwander T.   +3 more
europepmc   +1 more source

Increasing Paternal Age Associated With Elevated Risk of De Novo Mutations in Offspring Diagnosed With Sporadic Bilateral Retinoblastoma

Pediatric Blood &Cancer, Volume 72, Issue 10, October 2025.
ABSTRACT Background The impact of paternal exposures on de novo germline mutations leading to bilateral sporadic retinoblastoma in offspring is largely unknown. This malignancy results from mutations of both alleles of the RB1 tumor suppressor gene in a retinal cell.
Maral Adel Fahmideh, Arupa A. Ganguly, Tiffany M. Chambers, Greta R. Bunin, Philip J. Lupo   +4 more
wiley   +1 more source

Organotypic culture system for prepubertal mice testicular tissue: A comparative study. [PDF]

Front Endocrinol (Lausanne)
Deng L, Wang X, Wu X, Zhou H, Cheng Y, Li H.   +5 more
europepmc   +1 more source

SLB‐msSIM: A Spectral Library‐Based Multiplex Segmented SIM Platform for Single‐Cell Proteomic Analysis

PROTEOMICS, Volume 25, Issue 19, Page 50-61, October 2025.
ABSTRACT Mass spectrometry (MS)‐based single‐cell proteomics, while highly challenging, offers unique potential for a wide range of applications to interrogate cellular heterogeneity, trajectories, and phenotypes at a functional level. We report here the development of the spectral library‐based multiplex segmented selected ion monitoring (SLB‐msSIM ...
Lakmini Senavirathna, Cheng Ma, Van‐An Duong, Hong‐Yuan Tsai, Ru Chen, Sheng Pan   +5 more
wiley   +1 more source

Gut Microbial Genetic Variation Regulates Host Reproduction

Microbial Biotechnology, Volume 18, Issue 10, October 2025.
We discovered that microbial genetic variation interacts with host genetics to regulate host reproduction. We identified E. coli mutants that mitigate cyclophosphamide‐induced male reproductive toxicity and found that the purine metabolism pathway may contribute to it.
Xiaoyue Ding, Yalun Wu, Dianshuang Zhou, Rongrong Gu, Tao Zhu, Wen Cai, Yuxuan Ren, Ying Li, Chuhe Wang, Anqi Tan, Ying Li, Zuobin Zhu   +11 more
wiley   +1 more source

Curcumin promotes spermatogenesis in mice with cryptorchidism by regulating testicular protein <i>O</i>-GlcNAcylation. [PDF]

Front Endocrinol (Lausanne)
Wang Z, Chen F, Li Y, Liu C, Wang L, Shao W, Lu Z, Hu L, Li L, Wang Y, Lin J, Yu Y, Sun S, Yang Y, Zhu Z, Li S, Li E.   +16 more
europepmc   +1 more source

EP300‐interacting inhibitor of differentiation 3 is required for spermatogenesis in mice

Andrology, Volume 13, Issue 7, Page 1901-1912, October 2025.
Abstract Background Mammalian spermatogenesis is a highly complex process of cell proliferation, meiosis, and differentiation. A series of genes are expressed in an orderly and precise manner to ensure spermatogenesis, with chromatin undergoing intricate changes throughout.
Ping Zhang, Longsheng Zhang, Li Yu, Xinli Zhou, Xu Chen, Yuchuan Zhou, Ningling Wang, Hui Zhu   +7 more
wiley   +1 more source