Results 231 to 240 of about 84,845 (296)
ABSTRACT Background More than 1000 genes have been identified as predominantly expressed in the human testis. Advances in gene editing technologies have enabled the rapid and efficient generation of genetically engineered mice. This approach facilitates the screening of genes essential for spermatogenesis by analyzing knockout mouse models.
Yumiao Qiu +2 more
wiley +1 more source
Fertility preservation in prepubertal boys: management and follow-up challenges. [PDF]
Ferrari V +3 more
europepmc +1 more source
ABSTRACT Background Asthenozoospermia is a significant contributing factor to male infertility. Accumulating evidence indicates that impaired sperm motility is closely linked to dysregulated microRNA expression during spermatogenesis. Seminal plasma exosomes are enriched with diverse microRNAs, which play pivotal roles in modulating sperm motility, the
Zhi‐Jian Zhu +8 more
wiley +1 more source
WSB1 is dispensable for mouse spermatogenesis and male fertility. [PDF]
Qu W +6 more
europepmc +1 more source
Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan +10 more
wiley +1 more source
Characteristic spermatogenesis process observed in Gasterosteidae: Considerations from histological observations of the testes and serum androgen levels of nine-spined stickleback, Pungitius sinensis. [PDF]
Nagaya M, Yambe H, Koya Y.
europepmc +1 more source
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben +3 more
wiley +1 more source
Association Between Leukocytospermia and Varicocele in Patients With Infertility. [PDF]
Eldamnhoury EM, El-Sakka AI.
europepmc +1 more source
Chromodomain Helicase DNA–Binding Proteins and Spermatogenesis: Current Advances
ABSTRACT Background Male infertility is a prevalent clinical condition, with approximately one‐third of cases classified as idiopathic, frequently stemming from impaired spermatogenesis because of dysregulated gene expression. Chromodomain helicase DNA‐binding (CHD) proteins are central chromatin remodelers that orchestrate this epigenetic regulation ...
Mingrui Zhang +4 more
wiley +1 more source
Metabolic Syndrome and Male Infertility: The Role of Obesity and Chronic Inflammation. [PDF]
Behera S +8 more
europepmc +1 more source

