Results 251 to 260 of about 66,364 (295)

Semen cryopreservation and storage in liquid nitrogen: Impact on chromatin compaction

Andrology, Volume 13, Issue 7, Page 1780-1796, October 2025.
Abstract Background Sperm cryopreservation is a consolidate option for long‐term male fertility preservation. The freezing/thawing procedure causes detrimental effects to spermatozoa, including damage to viability, motility, membrane composition, and DNA, whereas the effect on sperm chromatin compaction is less studied.
Lara Tamburrino, Giulia Traini, Maria Emanuela Ragosta, Sara Dabizzi, Sara Vezzani, Flavia Scarpa, Linda Vignozzi, Elisabetta Baldi, Sara Marchiani   +8 more
wiley   +1 more source

Inhibition of ROS1 activity with lorlatinib reversibly suppresses fertility in male mice

Andrology, Volume 13, Issue 7, Page 1891-1900, October 2025.
Abstract Background Inhibition of sperm maturation in the epididymis is a promising post‐testicular strategy for short‐acting male contraceptives. It has been shown that ROS1, a receptor tyrosine kinase expressed in the epididymis, is essential for epididymal differentiation, sperm maturation, and male fertility in mice.
Yuki Oyama, Kentaro Shimada, Haruhiko Miyata, Rie Iida‐Norita, Chihiro Emori, Maki Kamoshita, Seiya Oura, Ryohei Katayama, Martin M. Matzuk, Masahito Ikawa   +9 more
wiley   +1 more source

Testicular immunosenescence: a key player in age-related spermatogenic decline. [PDF]

Front Cell Dev Biol
Zhan MW, Zhou MH, Zhao BB, Bao XJ, Chen Y, Zhu J.   +5 more
europepmc   +1 more source

Effects of AZFc (b2/b4, b1/b3, b2/b3, and gr/gr) deletions and primary duplications on the outcomes of the first intracytoplasmic sperm injection treatment cycle: A single‐center retrospective cohort study

Andrology, Volume 13, Issue 7, Page 1757-1771, October 2025.
Abstract Background Current advances in high‐throughput sequencing technology enable the precise identification of Y chromosome microdeletion and primary duplication in infertile couples, but the mechanism and clinical significance of these mutations in assisted reproductive techniques remain unclear.
Linlin Li, Xiangyin Liu, Xinying Wang, Hongguo Zhang, Ruizhi Liu   +4 more
wiley   +1 more source

Glycerol Kinase 2 as a Metabolic Sentinel for Human Sperm Motility and Male Fertility. [PDF]

Biomolecules
Oliveira JS, Moreira RJ, Martins AD, Alves MG, Oliveira PF.   +4 more
europepmc   +1 more source

Evaluation of dimethandrolone undecanoate in non‐human primates as a candidate for long‐acting injectable male contraceptive

Andrology, Volume 13, Issue 7, Page 1919-1934, October 2025.
Abstract Background Dimethandrolone undecanoate (DMAU) is under development as a single agent hormonal male contraceptive. DMAU is a prodrug hydrolyzed by esterase(s) to the active metabolite dimethandrolone (DMA) which has dual androgenic and progestogenic actions.
Deborah I. Bunin, Kyuri Kim, Toufan Parman, Janet Gahagen, Mary B. Zelinski, Tiffany Adevai, Christina Wang, Liang Tang, Lalitha Iyer, Aaron Endsley, Diana L. Blithe, Min S. Lee   +11 more
wiley   +1 more source

Cuproptosis and cuproptosis-related cell death and genes: mechanistic links to spermatogenic cell death. [PDF]

Cell Death Discov
Li J, Li N, Wang H, Li B, Tang X, Guan Y, Yang F, Li G, Dong L, Yuan R, Yu X.   +10 more
europepmc   +1 more source

Cryopreservation and culture strategies for testicular tissue and cells in small and large animals. [PDF]

Front Vet Sci
Vurchio V, Colombo M, Pasquariello R, Luvoni GC.   +3 more
europepmc   +1 more source

Ybx1 deficiency impairs spermatid development and male fertility without affecting meiosis in mice: insights into spermatogenesis. [PDF]

J Reprod Dev
Han Y, Wu R, Duan C, Chen J, Deng X, Peng W, Tan B.   +6 more
europepmc   +1 more source

Dcun1d3 is dispensable for spermatogenesis and male fertility in mice. [PDF]

Am J Clin Exp Immunol
Liu M, Gao W, Sheng W, Zhou N, Wu T, Shen C, Feng G, Xi X.   +7 more
europepmc   +1 more source