Results 271 to 280 of about 90,893 (356)

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, Volume 20, Issue 6, Page 1556-1590, June 2026.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

The Guangsi Yulin Decoction Inhibits Oxidative Stress and Inflammation-Induced Spermatogenesis Dysfunction <i>via</i> the <i>PTEN</i>/<i>PI3K</i>/<i>AKT</i>/<i>FoxO1</i> Pathway. [PDF]

Am J Mens Health
Lin X, Feng J, Chang H, Chen H, Huang N, Li K, Chen M, Li H, Wang L, Wang J.   +9 more
europepmc   +1 more source

Role of copper in the process of spermatogenesis

, 2017
Mateusz Ogórek, Łukasz Gąsior, Olga Pierzchała, Regina Daszkiewicz, Małgorzata Lenartowicz   +4 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, Volume 16, Issue 6, Page 1087-1101, June 2026.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

Immunization Against a Conserved Short 13-Amino Acid Receptor-Binding Epitope of FSHβ Reduces Spermatogenesis and Sperm Motility in Male Mice. [PDF]

Vaccines (Basel)
Liu X, Ran L, He J, Lei S, Zhang J, Yang Z, Han X.   +6 more
europepmc   +1 more source

Conservation Status of Two Italian Local Poultry Breeds: Faraona Camosciata and Oca Padovana

Animal Genetics, Volume 57, Issue 3, June 2026.
ABSTRACT The present study aimed to assess the conservation status and characterize the phenotypic and genomic diversity of two endangered Italian poultry genetic resources to guide their conservation plans. Blood samples and morphometric data were collected on 50 Faraona Camosciata (FAC, Numida meleagris) and 50 Oca Padovana (OPD, Anser anser) adult ...
Filippo Cendron, Enrico Bortoletto, Francesco Perini, Maristella Baruchello, Umberto Rosani, Emiliano Lasagna, Martino Cassandro, Mauro Penasa   +7 more
wiley   +1 more source

miRNA Sequencing and Differential Analysis of Testis in 1-Year-Old and 2-Year-Old Kazakh Horses. [PDF]

Biology (Basel)
Zhou Y, Wen L, Ren W, Wen M, Ming M, Wang J, Meng J, Yao X, Zeng Y.   +8 more
europepmc   +1 more source

Clinicopathological Features, Treatment Patterns, and Long‐Term Survival in Patients With Testicular Cancer: A Retrospective Cohort Study

Cancer Reports, Volume 9, Issue 6, June 2026.
ABSTRACT Background Testicular cancer represents the most common solid tumor in young adult males and is associated with excellent long‐term survival outcomes. Aim The aim of this study is to evaluate clinical and pathological characteristics, treatment strategies, and survival outcomes of a large Romanian institutional cohort.
Emanuiela Florentina Rohozneanu, Ciprian Deac, Călin Ioan Căinap   +2 more
wiley   +1 more source

Stigmasterol from Pluchea indica Leaves Reduces Spermatogenesis and Alters Sperm Morphology in Male Rat: In Vivo and In Silico Study. [PDF]

F1000Res
Wahyono P, Ariesaka KM, Susetyarini E, Husamah H.   +3 more
europepmc   +1 more source

Putative Genomic Signatures of Local Adaptation in Five Local Indonesian Sheep Reveal Selection on Immunity, Reproduction, and Production Traits

Ecology and Evolution, Volume 16, Issue 6, June 2026.
We determined the genetic structure and signatures of selection in five local Indonesian sheep breeds using genome‐wide SNP data. By integrating population structure analyses with runs of homozygosity and haplotype‐based selection scans, we identified breed‐specific genomic regions associated with immunity, reproduction, pigmentation, metabolism, and ...
Putri Kusuma Astuti, Alexandru Eugeniu Mizeranschi, Herdis Herdis, Pradita Iustitia Sitaresmi, Alek Ibrahim, Sigit Prastowo, Nuzul Widyas, Tristianto Nugroho, Szilvia Kusza   +8 more
wiley   +1 more source