ABSTRACT Sex determination in Porifera remains one of the least understood aspects of early metazoan biology despite the group's key phylogenetic position. Sponges display exceptional diversity in sexual systems—ranging from stable gonochorism to sequential hermaphroditism and sex reversal—yet lack morphological dimorphism and any discrete gonadal ...
Jose M. Lorente‐Sorolla, Ana Riesgo
wiley +1 more source
A scoping review of imatinib-induced testicular toxicity and male fertility impairment. [PDF]
Ji X +4 more
europepmc +1 more source
Sequence and structural alignments reveal insights into ANKLE2 evolution and function
Abstract ANKLE2 is an enigmatic protein with emerging roles in cell division, development, and virus replication. While ANKLE2 orthologs are present in all animals, its domain composition has evolved over time. ANKLE2's two namesake domains, the ankyrin repeat and LEM domains (named for LAP2, Emerin, and MAN1), have clear and defined roles; however ...
Adam T. Fishburn +8 more
wiley +1 more source
Comparative analysis of mRNA and circRNA expression profiles and interaction networks in testicular tissues of Mongolian horses before and after sexual maturity. [PDF]
Du M +10 more
europepmc +1 more source
SOX30 Governs Synaptonemal Complex Assembly and Homologous Recombination in Male Meiosis
The transcription factor SOX30 directly binds promoter regions of SYCE1 and SYCE2 to mediate their transcriptional activation, thereby enabling proper assembly of central elements within the synaptonemal complex. Structural destabilisation of the synaptonemal complex in Sox30 KK spermatocytes triggers synaptic discontinuity, impairs homologous ...
Kangle Liu +16 more
wiley +1 more source
Comparison of Sertoli cells in duck testes pre- and post-sexual maturation. [PDF]
Tao Z +9 more
europepmc +1 more source
GGAs: Regulation of Multiple Sorting Pathways and Potential Association With Human Diseases
ABSTRACT Golgi‐localized gamma‐ear‐containing Arf‐binding proteins (GGAs) are a family of monomeric clathrin adaptors that function in intracellular vesicle trafficking. The three GGA family members—GGA1, GGA2 and GGA3—were first identified as sorting adaptors almost simultaneously by independent research groups in 2000. It is now well established that
Qinqin Wang +5 more
wiley +1 more source
Advances in the diagnosis and treatment of oligoasthenozoospermia based on epigenetic regulation. [PDF]
Zhao HB +5 more
europepmc +1 more source
Scrotal Botulinum Toxin Exposure and Male Fertility: Mechanistic Insights and Clinical Evidence. [PDF]
Azeem A +5 more
europepmc +1 more source
Spatially resolved micromechanical characterisation of human testis tissue reveals distinct signatures across developing, adult and pathological tissue states. [PDF]
Andersson I +14 more
europepmc +1 more source

