Results 41 to 50 of about 102,741 (261)

Antipsychotics and spermatogenesis, which is the impact?: A review of literature

European Psychiatry, 2023
Introduction Antipsychotics are among the most widely prescribed molecules in psychiatry. Their sexual side effects are frequent, generally underestimated by clinicians and subjectively poorly tolerated by patients.
H. Belhadga, Z. Elmaataoui, H. Kisra
doaj   +1 more source

A Comprehensive Roadmap of Murine Spermatogenesis Defined by Single-Cell RNA-Seq.

Developmental Cell, 2018
Spermatogenesis requires intricate interactions between the germline and somatic cells. Within a given cross section of a seminiferous tubule, multiple germ and somatic cell types co-occur.
C. D. Green, Qianyi Ma, Gabriel Manske, A. Shami, Xianing Zheng, S. Marini, Lindsay Moritz, Caleb Sultan, S. Gurczynski, B. Moore, M. Tallquist, Jun Z. Li, S. S. Hammoud   +12 more
semanticscholar   +1 more source

Follicle-Stimulating Hormone (FSH) Action on Spermatogenesis: A Focus on Physiological and Therapeutic Roles

Journal of Clinical Medicine, 2020
Background: Human reproduction is regulated by the combined action of the follicle-stimulating hormone (FSH) and the luteinizing hormone (LH) on the gonads.
D. Santi, P. Crépieux, E. Reiter, G. Spaggiari, G. Brigante, L. Casarini, V. Rochira, M. Simoni   +7 more
semanticscholar   +1 more source

The Prmt5-Vasa module is essential for spermatogenesis in Bombyx mori.

PLoS Genetics, 2023
In lepidopteran insects, dichotomous spermatogenesis produces eupyrene spermatozoa, which are nucleated, and apyrene spermatozoa, which are anucleated.
Xu Yang, Dongbin Chen, Shirui Zheng, Meiyan Yi, Shanshan Wang, Yongjian Liu, Lianyan Jing, Zulian Liu, Dehong Yang, Yujia Liu, Linmeng Tang, James R Walters, Yongping Huang   +12 more
doaj   +1 more source

Single-Cell RNA Sequencing Analysis Reveals Sequential Cell Fate Transition during Human Spermatogenesis.

Cell Stem Cell, 2018
Spermatogenesis generates mature male gametes and is critical for the proper transmission of genetic information between generations. However, the developmental landscapes of human spermatogenesis remain unknown.
Mei Wang, Xixi Liu, Gang Chang, Yidong Chen, G. An, Liying Yan, Shuai Gao, Yanwen Xu, Yueli Cui, Ji Dong, Yuhan Chen, Xiaoying Fan, Yuqiong Hu, Ke Song, Xiaohui Zhu, Yun Gao, Zhaokai Yao, Shuhui Bian, Yu Hou, Jiahao Lu, Rui Wang, Yong Fan, Y. Lian, Wenhao Tang, Yapeng Wang, Jianqiao Liu, Lianming Zhao, Lu-lin Wang, Zhaoting Liu, Ren-pei Yuan, Yujia Shi, Boqiang Hu, Xiulian Ren, Fuchou Tang, Xiaoyang Zhao, J. Qiao   +35 more
semanticscholar   +1 more source

Improvement in sperm quality and spermatogenesis following faecal microbiota transplantation from alginate oligosaccharide dosed mice

Gut, 2020
Very recent publications in Gut and elsewhere1 2 suggest that gut microbiota affects fertility. The application of faecal microbiota transplantation (FMT) to modify fertility is an emerging novel area of interest.3 FMT from women with polycystic ovary ...
Pengfei Zhang, Yanni Feng, Lan Li, Wei Ge, Shuai Yu, Yanan Hao, W. Shen, Xiao Han, Dongxue Ma, S. Yin, Yu Tian, Lingjiang Min, Zhong-Yi Sun, Qingyuan Sun, Hongfu Zhang, Yong Zhao   +15 more
semanticscholar   +1 more source

Alginate oligosaccharides improve germ cell development and testicular microenvironment to rescue busulfan disrupted spermatogenesis

Theranostics, 2020
Rationale: Busulfan is currently an indispensable anti-cancer drug, particularly for children, but the side effects on male reproduction are so serious that critical drug management is needed to minimize any negative impact.
Yong Zhao, Pengfei Zhang, Wei Ge, Yanni Feng, Lan Li, Zhong-Yi Sun, Hongfu Zhang, W. Shen   +7 more
semanticscholar   +1 more source

Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

iScience, 2021
Summary: Maintaining proteostasis is important for animal development. How proteostasis influences spermatogenesis that generates male gametes, spermatozoa, is not clear.
Qianxing Zou, Lele Yang, Ruona Shi, Yuling Qi, Xiaofei Zhang, Huayu Qi   +5 more
doaj   +1 more source

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

Cell Research, 2018
A systematic interrogation of male germ cells is key to complete understanding of molecular mechanisms governing spermatogenesis and the development of new strategies for infertility therapies and male contraception. Here we develop an approach to purify
Yao Chen, Yuxuan Zheng, Yun Gao, Zhen Lin, Suming Yang, Tongtong Wang, Qiu Wang, Nannan Xie, Rong Hua, Mingxi Liu, J. Sha, M. Griswold, Jinsong Li, Fuchou Tang, M. Tong   +14 more
semanticscholar   +1 more source