Results 51 to 60 of about 168,606 (377)

Antipsychotics and spermatogenesis, which is the impact?: A review of literature

European Psychiatry, 2023
Introduction Antipsychotics are among the most widely prescribed molecules in psychiatry. Their sexual side effects are frequent, generally underestimated by clinicians and subjectively poorly tolerated by patients.
H. Belhadga, Z. Elmaataoui, H. Kisra
doaj   +1 more source

An update on the potential for male contraception : emerging options [PDF]

, 2013
The human population continues to grow and is estimated to rise to 10.1 billion by the end of the century. Therefore, there is still an unmet need for safe and highly effective contraceptive options for both men and women.
Alsaadi, Manal, Ferro, Valerie, Garside, Deborah A, Gebril, Ayman M, Mullen, Alexander, Nimmo, Natalie   +5 more
core   +1 more source

Loss-of-function analysis reveals distinct requirements of the translation initiation factors eIF4E, eIF4E-3, eIF4G and eIF4G2 in Drosophila spermatogenesis. [PDF]

PLoS ONE, 2015
In eukaryotes, post-transcriptional regulation of gene expression has a key role in many cellular and developmental processes. Spermatogenesis involves a complex developmental program that includes changes in cell cycle dynamics and dramatic cellular ...
Sanjay Ghosh, Paul Lasko
doaj   +1 more source

Contribution of recent transgenic models and transcriptional profiling studies to our understanding of the mechanisms by which androgens control spermatogenesis [PDF]

, 2008
Publisher ...
Claessens, Frank, De Gendt, Karel, Denolet, Evi, Saunders, Philippa T K, Sharpe, Richard, Swinnen, Johannes V, Verhoeven, Guido, Willems, Ariane   +7 more
core   +1 more source

Single-cell RNA-seq uncovers dynamic processes and critical regulators in mouse spermatogenesis

Cell Research, 2018
A systematic interrogation of male germ cells is key to complete understanding of molecular mechanisms governing spermatogenesis and the development of new strategies for infertility therapies and male contraception. Here we develop an approach to purify
Yao Chen, Yuxuan Zheng, Yun Gao, Zhen Lin, Suming Yang, Tongtong Wang, Qiu Wang, Nannan Xie, Rong Hua, Mingxi Liu, J. Sha, M. Griswold, Jinsong Li, Fuchou Tang, M. Tong   +14 more
semanticscholar   +1 more source

Follicle-Stimulating Hormone (FSH) Action on Spermatogenesis: A Focus on Physiological and Therapeutic Roles

Journal of Clinical Medicine, 2020
Background: Human reproduction is regulated by the combined action of the follicle-stimulating hormone (FSH) and the luteinizing hormone (LH) on the gonads.
D. Santi, P. Crépieux, E. Reiter, G. Spaggiari, G. Brigante, L. Casarini, V. Rochira, M. Simoni   +7 more
semanticscholar   +1 more source

Epi-mutations for spermatogenic defects by maternal exposure to di(2-ethylhexyl) phthalate

eLife, 2021
Exposure to environmental factors during fetal development may lead to epigenomic modifications in fetal germ cells, altering gene expression and promoting diseases in successive generations.
Yukiko Tando, Hitoshi Hiura, Asuka Takehara, Yumi Ito-Matsuoka, Takahiro Arima, Yasuhisa Matsui   +5 more
doaj   +1 more source

Improvement in sperm quality and spermatogenesis following faecal microbiota transplantation from alginate oligosaccharide dosed mice

Gut, 2020
Very recent publications in Gut and elsewhere1 2 suggest that gut microbiota affects fertility. The application of faecal microbiota transplantation (FMT) to modify fertility is an emerging novel area of interest.3 FMT from women with polycystic ovary ...
Pengfei Zhang, Yanni Feng, Lan Li, Wei Ge, Shuai Yu, Yanan Hao, W. Shen, Xiao Han, Dongxue Ma, S. Yin, Yu Tian, Lingjiang Min, Zhong-Yi Sun, Qingyuan Sun, Hongfu Zhang, Yong Zhao   +15 more
semanticscholar   +1 more source

Smoke, alcohol and drug addiction and male fertility [PDF]

, 2018
In recent decades, the decline in human fertility has become increasingly more worrying: while therapeutic interventions might help, they are vexing for the couple and often burdened with high failure rates and costs.
DE ANGELIS, Cristina Concetta, Di Dato, Carla, Gianfrilli, Daniele, Isidori, Andrea, Menafra, Davide, Pivonello, Rosario, Pozza, Carlotta, Sansone, Andrea   +7 more
core   +1 more source

Alginate oligosaccharides improve germ cell development and testicular microenvironment to rescue busulfan disrupted spermatogenesis

Theranostics, 2020
Rationale: Busulfan is currently an indispensable anti-cancer drug, particularly for children, but the side effects on male reproduction are so serious that critical drug management is needed to minimize any negative impact.
Yong Zhao, Pengfei Zhang, Wei Ge, Yanni Feng, Lan Li, Zhong-Yi Sun, Hongfu Zhang, W. Shen   +7 more
semanticscholar   +1 more source