Results 81 to 90 of about 66,364 (295)
P4‐ATPases as Phospholipid Flippases: From Membrane Dynamics to Human Disorders
Medicine Bulletin, EarlyView.ABSTRACT P4‐ATPases (P4 subfamily of P‐type ATPases) flippase complex includes an α‐subunit responsible for catalysis and a supporting β‐subunit, which consumes energy by catalyzing the hydrolysis of ATP, thereby facilitating the translocation of aminophospholipids from the outer to the inner leaflet of cellular membranes to maintain the asymmetric ...
Guangyi Chen, Yeming Yang, Xianjun Zhu
wiley +1 more source
Molecular Nutrition &Food Research, EarlyView.This review highlights the emerging connection between paternal nutrition‐induced sperm epigenetic changes and placental phenotypes that may influence offspring metabolic health. An accompanying interactive ShinyApp allows exploration of these sperm–placenta gene networks, a framework for future research seeking to explore candidate biomarkers or ...
David A. Skerrett‐Byrne +6 more
wiley +1 more source
LncRNA4667 is dispensable for spermatogenesis and fertility in mice
Reproductive and Developmental Medicine, 2019 Objective: Spermatogenesis is a complex process which is of vital importance for sexual reproduction. In many studies of spermatogenesis, the mRNAs, protein-coding genes, as well as small noncoding RNAs (ncRNAs) have been well characterized.
Yu-Bing Dai, Yu Lin, Ning Song, Fei Sun
doaj +1 more source
Molecular Nutrition &Food Research, EarlyView.Sulfated polysaccharides from red seaweed improved testicular FSH and insulin signaling, which upregulated GLUT4 level and improved glycolysis and energy metabolism in testes of diabetic rats. ABSTRACT Testicular glucose homeostasis plays important roles in testicular energy metabolism and male fertility, but it is altered in type 2 diabetes (T2D ...
Ochuko L. Erukainure +5 more
wiley +1 more source
Obesity, EarlyView.ABSTRACT Objective We investigated the associations of grandmaternal early pregnancy BMI with grand‐offspring risks of birth asphyxia‐related complications. Methods In a nationwide three‐generation Swedish cohort, we estimated adjusted relative risks (RRs) of Apgar score 0–3 at 5 min and neonatal seizures for categories of grandmaternal BMI among 315 ...
Eduardo Villamor +2 more
wiley +1 more source
Impacts of morphine addiction on spermatogenesis in rats
Iranian Journal of Reproductive Medicine, 2016 Background: There are numerous investigations on wide range of issues that disrupt regulatory spermatogenesis, individuals who are exposed to drug abuse faced infertility and immature spermatogenesis. Objective: The aim of this study was to evaluate the
Nasrin Takzare +6 more
doaj
Prenatal Diagnosis, EarlyView.ABSTRACT Objectives Achondroplasia is the most common form of skeletal dysplasia and is usually suspected in the third trimester of pregnancy based on abnormal sonographic findings. Non‐invasive prenatal diagnosis (NIPD), based on the detection of pathogenic FGFR3 variants in maternal plasma, provides an accurate genetic confirmation.
Camille Verebi +12 more
wiley +1 more source
Key Regulators of Parasite Biology Viewed Through a Post‐Translational Modification Repertoire
PROTEOMICS, EarlyView.ABSTRACT Parasites are the leading causes of morbidity and mortality in both humans and animals, imposing substantial socioeconomic burdens worldwide. Controlling parasitic diseases has become one of the key issues in achieving “One Health”. Most parasites have sophisticated life cycles exhibiting progressive developmental stages, morphologies, and ...
Naiwen Zhang, Ning Jiang, Qijun Chen
wiley +1 more source
Environmental Toxicology, EarlyView.ABSTRACT Cadmium (Cd), a heavy metal, disrupts the structure of seminiferous tubules and induces cell death at multiple stages of sperm development. Cd also impairs Leydig cells (LCs), resulting in reduced serum testosterone (T) levels. This study primarily examined the impact of Cd on the mitochondrial compartment and mitochondrial‐associated ...
Debora Latino +7 more
wiley +1 more source