Results 91 to 100 of about 52,517 (253)

Impact of Chemotherapy on Sperm Functional Characteristics in Patients With Testicular Germ Cell Tumours

Andrology, EarlyView.
ABSTRACT Background Testicular germ cell tumours (TGCT) are the most common malignancies among young men and represent a major threat to reproductive health. Both the disease itself and oncological treatments, particularly chemotherapy, can compromise spermatogenesis and semen quality.
Ondrej Sanovec, Ondrej Simonik, Zuzana Kratka, Lukas Ded, Jana Vondrakova, Maryam Qasemi, Barbora Bryndova, Michala Krejci, Daniela Spevakova, Vishma Pratap Sur, Radomir Kren, Tomas Hradec, Pavel Skrobanek, Ludmila Boublikova, Libor Zamecnik, Tomas Buchler, Jiri Neuzil, Pavla Postlerova, Katerina Komrskova   +18 more
wiley   +1 more source

Testicular sperm results in elevated miscarriage rates compared to epididymal sperm in azoospermic patients

São Paulo Medical Journal
CONTEXT: Several sperm retrievel techniques are available for use on azoospeermic men. Comparisons between spermatozoa retrieved from the testicles and epidymis in relation to pregnancy and miscarriage rates are not well established.
Edson Borges Júnior, Lia Mara Rossi-Ferragut, Fábio Firmbach Pasqualotto, Daniela Regina dos Santos, Cláudia Chagas Rocha, Assumpto Iaconelli Júnior   +5 more
doaj   +1 more source

Nut Consumption and Sperm Quality in Healthy Men: Results From the Led‐Fertyl Study

Andrology, EarlyView.
ABSTRACT Background Nuts are rich in antioxidants and other bioactive compounds, and recent evidence suggests that their regular consumption may be associated with sperm quality. However, the current scientific evidence remains limited and inconsistent.
Estefanía Dávila‐Córdova, Nancy Babio, Cristina Valle‐Hita, María Fernández de la Puente, Alfonso Beltran‐Arasa, Miguel Cebrián‐Puig, Violeta Fambuena‐Perez, Iván García‐Serrano, Michelle M. Murphy, Jordi Salas‐Salvadó, Albert Salas‐Huetos   +10 more
wiley   +1 more source

Peroxiredoxin 4 Involved in Spermatogenesis by Affecting Oxidative Stress and Ferroptosis

Andrology, EarlyView.
ABSTRACT Background The main functions of testes are sperm production and androgen secretion in testicular befitting microenvironment. Excessive level of the reactive oxygen species (ROS) from metabolism and cellular events can lead to oxidative stress (OS) and ferroptosis, which injure the functions of mitochondria and endoplasmic reticulum (ER) of ...
Shuning Yuan, Nini Wei, Weiwei Ma, Mengting Hu, Bei Zhang, Li Gao, Chao Gao, Xiaoyu Yang, Yan Meng, Jiayin Liu, Yugui Cui   +10 more
wiley   +1 more source

Boosting Male Fertility: The Impact of Gonadotropin Therapy on Hypogonadotropic Hypogonadism—A Systematic Review and Meta‐Analysis

Andrology, EarlyView.
ABSTRACT Background Male hypogonadotropic hypogonadism typically presents with azoospermia and is one of the few causes of infertility amenable to a medical intervention. Gonadotropin therapy offers a chance to restore spermatogenesis and fertility in these individuals.
Manou Huijben, Anne Prinsen, Laetitia de Kort, Jetske van Breda   +3 more
wiley   +1 more source

Hyperactivation and Tyrosine Phosphorylation of Cryopreserved Stallion Spermatozoa in Relation to Conventional In Vitro Fertilization Blastocyst Production

Andrology, EarlyView.
ABSTRACT Background Challenges in establishing clinical conventional in vitro fertilization (IVF) in horses include variation in sperm and oocyte quality, which can be affected by mare age. Extended preincubation of stallion spermatozoa has resulted in successful IVF.
Raul A. Gonzalez‐Castro, Carolina C. Porflidt, Alexandra L. Ash, Jacobo S. Rodriguez, Perla D. Fleury, Edward L. Squires, Elaine M. Carnevale   +6 more
wiley   +1 more source

Limited Clinical Impact of Androgen Receptor Repeat Length (CAG and GGC) in Klinefelter Syndrome: A Multivariable Analysis

Andrology, EarlyView.
ABSTRACT Background Klinefelter syndrome (KS) is characterized by marked phenotypic heterogeneity that might be influenced by genetic modifiers, including androgen receptor (AR) repeat length (CAGn and GGCn). The clinical relevance of these repeat lengths in patients with KS before testosterone replacement therapy (TRT) remains unclear.
Andrea Graziani, Alberto Scala, Maria Santa Rocca, Cinzia Vinanzi, Giuseppe Grande, Andrea Di Nisio, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +8 more
wiley   +1 more source

Impact of FSHB and FSHR Genes Polymorphisms on Hormonal Profile and Sperm Retrieval Outcome in Men With Klinefelter Syndrome: A Clinical–Genetic Predictive Study

Andrology, EarlyView.
ABSTRACT Background Genetic variability within the follicle‐stimulating hormone (FSH)‐related genes might contribute to phenotypic heterogeneity in patients with Klinefelter syndrome (KS), yet its clinical impact on sperm retrieval remains unclear. Objectives To investigate the association between FSHB c.211 G > T and FSHR polymorphisms (c.2039 A > G ...
Andrea Graziani, Giuseppe Grande, Maria Santa Rocca, Massimo Iafrate, Riccardo Selice, Antonella Di Mambro, Alberto Ferlin   +6 more
wiley   +1 more source

Loss‐of‐Function Variants in CCDC189 Cause Human Oligoasthenoteratozoospermia by Disrupting Sperm Flagellar and Acrosomal Architecture

Andrology, EarlyView.
ABSTRACT Background Oligoasthenoteratozoospermia (OAT), characterized by reduced sperm count, impaired motility, and abnormal morphology, is a major cause of male infertility with substantial genetic heterogeneity. However, the underlying genetic etiology remains unresolved in a large proportion of affected individuals.
Jianteng Zhou, Ghulam Mustafa, Tingting Lin, Jingwei Ye, Huan Zhang, Hanwei Jiang, Kexin Yang, Guoning Huang, Qinghua Shi   +8 more
wiley   +1 more source

Intrauterine Growth and Male Reproductive Health: A Follow‐up Study From the Danish National Birth Cohort

Andrology, EarlyView.
ABSTRACT Background Reduced intrauterine growth might affect male reproductive health later in life, however, existing research remain inconclusive. Objectives To investigate the association between placental weight and birthweight Z‐scores and semen characteristics, testes volume, and reproductive hormone levels in young men.
Anne Gaml‐Sørensen, Nis Brix, Andreas Ernst, Sandra Søgaard Tøttenborg, Mette Møller Dornfeldt, Karin Sørig Hougaard, Siri Eldevik Håberg, Mikko Myrskylä, Gunnar Toft, Jens Peter Ellekilde Bonde, Cecilia Høst Ramlau‐Hansen   +10 more
wiley   +1 more source