Results 111 to 120 of about 129,614 (356)

Cellular basis of defective sperm function and its association with the genesis of reactive oxygen species by human spermatozoa.

open access: yesJournal of Reproduction and Fertility, 1987
Addition of the divalent cation ionophore, A23187, to washed populations of human spermatozoa resulted in a sudden burst of production of reactive oxygen species which peaked within 3-5 min. This activity was dependent upon the presence of calcium in the
R. Aitken, J. S. Clarkson
semanticscholar   +1 more source

Cryopreservation of Murine Spermatozoa [PDF]

open access: yesILAR Journal, 2000
Cryopreservation of mouse sperm provides an economic option for preserving the large number of mouse strains now being generated by transgenic and targeted mutation methodologies. The ability of a spermatozoan cell to survive cryobiological preservation depends on general biophysical constraints that apply to all cells, such as the avoidance or ...
Critser, J K, Mobraaten, L E
openaire   +3 more sources

Recent Advances in Mammalian Olfactory Receptor Function and Structure

open access: yesSensory Neuroscience, EarlyView.
Olfactory receptors (ORs), a subset of G protein‐coupled receptors (GPCRs), mediate odor detection in sensory neurons and regulate diverse physiological functions across tissues. Their roles in metabolism, immunity, and neural processes underscore their therapeutic relevance. Recent high‐resolution Cryo‐EM studies have unveiled OR activation mechanisms,
Hongxi Qin   +9 more
wiley   +1 more source

Emerging trends in the management of non‐obstructive azoospermia

open access: yesUroPrecision, EarlyView.
Abstract Ten percent of infertile males have azoospermia, classified into obstructive and nonobstructive types, which require specific medical or surgical treatments. In nonobstructive azoospermia, advancements in microsurgery allow for effective sperm retrieval in about half of cases.
Mina Saad   +4 more
wiley   +1 more source

Actin in Human Spermatozoa [PDF]

open access: yesBiology of Reproduction, 1982
An actin-like material was extracted from human spermatozoa. The material comigrated with actin on sodium dodecylsulfate (SDS) polyacrylamide gel electrophoresis, and showed specific affinity for myosin. Purified anti-actin antibodies were used to localize actin to the posterior region of the sperm head and to the connecting piece, midpiece and ...
G. N. Clarke   +2 more
openaire   +3 more sources

Surgical outcomes in male reconstructive urology: The Qatar experience

open access: yesUroPrecision, EarlyView.
Abstract Introduction Obstructive azoospermia (OA) is a prevalent cause of male infertility in Qatar and globally, with vasectomy reversal (VV) and vasoepididymostomy (VE) being the primary surgical treatments. While microsurgical techniques have advanced, data from the Middle East remain limited, influenced by the region's distinct demographic and ...
Kareim Khalafalla   +8 more
wiley   +1 more source

Systematic review and meta‐analysis of COVID‐19 association with human semen quality: Changes in semen parameters pre‐ and post‐COVID

open access: yesUroPrecision, EarlyView.
Abstract Coronavirus disease (COVID‐19) is caused by the severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2), which may infect the cells through binding with the angiotensin‐converting enzyme 2 (ACE2) receptors that can also be found in the male reproductive organs.
Wempy Supit   +2 more
wiley   +1 more source

Glycopattern comparison of sperm and exosomes from conventional in vitro fertilization and rescue intracytoplasmic sperm injection: Enhancing sperm motility through exosome‐mediated glycan modulation

open access: yesVIEW, EarlyView.
Infertility is a global concern, with male factors contributing to nearly half of cases. This study compared glycopatterns of sperm and sperm‐derived exosomes from conventional IVF and rescue ICSI (RICSI) patients, revealing key differences in glycan expression.
Muhammad Anas Ramzan   +10 more
wiley   +1 more source

Ca2+ ionophore A23187 can make mouse spermatozoa capable of fertilizing in vitro without activation of cAMP-dependent phosphorylation pathways

open access: yesProceedings of the National Academy of Sciences of the United States of America, 2013
Significance Sperm capacitation enables spermatozoa to undergo the acrosome reaction and to exhibit vigorous motility called hyperactivation. At the molecular level, capacitation is associated with activation of a cAMP-dependent pathway and with the ...
H. Tateno   +6 more
semanticscholar   +1 more source

Accumulation of Microswimmers due to Their Collisions with a Surface [PDF]

open access: yesarXiv, 2008
In this letter we propose a kinematic model to show how collisions with a surface and rotational Brownian motion give rise to the accumulation of micro-swimmers near a surface. In this model, an elongated microswimmer invariably travels parallel to the surface after hitting it from any incident angle. It then swims away from the surface after some time,
arxiv  

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