Results 41 to 50 of about 38,872 (182)

Why couple infertility is historically a female‐driven problem?

Andrology, Volume 13, Issue 4, Page 675-680, May 2025.
Abstract Background The history of studies in the field of infertility represents a chapter of great interest in gender issues. Objectives This paper aims to delve deep into the historical roots of the aspect of gender inequality related to couple infertility, with a journey back in time, from classical antiquity to the contemporary age, reporting ...
Linda Vignozzi, Sarah Cipriani, Donatella Lippi   +2 more
wiley   +1 more source

Engineered nanoparticles potentials in male reproduction

Andrology, Volume 13, Issue 4, Page 694-705, May 2025.
Abstract Background The escalating prevalence of fertility problems in the aging population necessitates a comprehensive exploration of contributing factors, extending beyond environmental concerns, work‐related stress, and unhealthy lifestyles. Among these, the rising incidence of testicular disorders emerges as a pivotal determinant of fertility ...
Feifei Zhao, Mengyu Fan, Zhiyang Jing, Yanxu Zhang, Yanlin Wang, Congli Zhou, Yang Liu, Robert John Aitken, Xue Xia   +8 more
wiley   +1 more source

Phenotypic continuum and poor intracytoplasmic sperm injection intracytoplasmic sperm injection prognosis in patients harboring HENMT1 variants

Andrology, EarlyView.
Abstract Background Small RNAs interacting with PIWI (piRNAs) play a crucial role in regulating transposable elements and translation during spermatogenesis and are essential in male germ cell development. Disruptions in the piRNA pathway typically lead to severe spermatogenic defects and thus male infertility. The HENMT1 gene is a key player in piRNAs
Zeina Wehbe, Anne‐Laure Barbotin, Angèle Boursier, Caroline Cazin, Jean‐Pascal Hograindleur, Marie Bidart, Emeline Fontaine, Pauline Plouvier, Florence Puch, Véronique Satre, Christophe Arnoult, Selima Fourati Ben Mustapha, Raoudha Zouari, Nicolas Thierry‑Mieg, Pierre F. Ray, Zine‑Eddine Kherraf, Charles Coutton, Guillaume Martinez   +17 more
wiley   +1 more source

Innovative all‐in‐one exome sequencing strategy for diagnostic genetic testing in male infertility: Validation and 10‐month experience

Andrology, EarlyView.
Abstract Background Current guidelines indicate that patients with extreme oligozoospermia or azoospermia should be tested for chromosomal imbalances, azoospermia factor (AZF) deletions and/or CFTR variants. For other sperm abnormalities, no genetic diagnostics are recommended.
Manon S. Oud, Nicole de Leeuw, Dominique F. C. M. Smeets, Liliana Ramos, Godfried W. van der Heijden, Raoul G. J. Timmermans, Maartje van de Vorst, Tom Hofste, Marlies J. E. Kempers, Marijn F. Stokman, Kathleen W. M. D'Hauwers, Brigitte H. W. Faas, Dineke Westra   +12 more
wiley   +1 more source

Deep learning classification method for boar sperm morphology analysis

Andrology, EarlyView.
Abstract Background Boar semen quality emphasizes three major criteria: sperm concentration, motility, and morphology. Methods to analyze concentration and motility quickly and objectively readily exist, but few exist for analyzing morphology outside of subjective manual counting.
Alexandra Keller, McKenna Maus, Emma Keller, Karl Kerns   +3 more
wiley   +1 more source

Ascorbic acid 2‐glucoside improves survival, quality, and fertility of frozen‐thawed C57Bl/6J and C57Bl/6N mouse spermatozoa

Andrology, EarlyView.
Abstract Background Ascorbic acid 2‐glucoside (AA2G) is a stabilized form of ascorbic acid and a potent antioxidant. Ascorbic acid is present in the testes and epididymis and helps maintain the physiological integrity of reproductive organs. Its properties have been utilized to protect spermatozoa of different species from oxidative stress.
Marcello Raspa, Renata Paoletti, Ferdinando Scavizzi   +2 more
wiley   +1 more source

The Known and Unknown About Female Reproductive Tract Mucus Rheological Properties. [PDF]

Bioessays
Mucus viscosity changes as spermatozoa travel through the female reproductive tract to the egg in humans, bovines, mice, and other mammals. These changes may aid in spermatozoa navigation. However, limited information is available on the viscoelastic properties of female reproductive tract mucus, and consistent measurement techniques are lacking ...
Achinger L, Kluczynski DF, Gladwell A, Heck H, Zhang F, Good E, Waggoner A, Reinhart M, Good M, Moore D, Filatoff D, Dhar S, Nigro E, Flanagan L, Yadav S, Williams T, Ray A, Shah TA, Liberatore MW, Avidor-Reiss T.   +19 more
europepmc   +2 more sources

Rapid detection of mouse spermatogenic defects by testicular cellular composition analysis via enhanced deep learning model

Andrology, EarlyView.
Abstract Background Histological analysis of the testicular sections is paramount in infertility research but tedious and often requires months of training and practice. Objectives Establish an expeditious histopathological analysis of mutant mice testicular sections stained with commonly available hematoxylin and eosin (H&E) via enhanced deep learning
Nianfei Ao, Min Zang, Yue Lu, Yiping Jiao, Haoda Lu, Chengfei Cai, Xiangxue Wang, Xin Li, Minge Xie, Tingting Zhao, Jun Xu, Eugene Yujun Xu   +11 more
wiley   +1 more source

Healthy and unhealthy dietary patterns and sperm quality from the Led‐Fertyl study

Andrology, EarlyView.
Abstract Background Dietary patterns may affect sperm quality, but the scientific evidence is limited. Objective To evaluate the association between adherence to different a‐priori dietary patterns and sperm quality parameters in healthy reproductive‐age men.
Estefanía Davila‐Cordova, Albert Salas‐Huetos, Cristina Valle‐Hita, María Fernández de la Puente, María Ángeles Martínez, Antoni Palau‐Galindo, Claudia Del Egido‐González, José María Manzanares‐Errazu, Elena Sánchez‐Resino, Jordi Salas‐Salvadó, Nancy Babio   +10 more
wiley   +1 more source

Safety concerns of paternal drug exposure on fertility, pregnancy and offspring: An analysis based on the FDA adverse event reporting system

Andrology, EarlyView.
Abstract Background Growing evidence indicates that paternal condition significantly influences pregnancy outcomes and offspring health. However, assessing the safety of paternal drug exposure via randomized controlled trials poses ethical challenges, and relevant clinical studies consume a lot of resources to evaluate only a few drugs.
Yanbin Zeng, Wanlong Lin, Wei Zhuang
wiley   +1 more source