Results 121 to 130 of about 71,184 (285)

POTENSI SENYAWA BIOAKTIF RAMBUT JAGUNG (Zea mays L.) UNTUK TABIR SURYA ALAMI : KAJIAN PUSTAKA

Jurnal Pangan dan Agroindustri, 2015
Semua bagian jagung dapat dimanfaatkan termasuk rambutnya. Rambut jagung (Zea mays L.) merupakan perpanjangan stigma dari bunga betina tanaman jagung. Selama ini pemanfaatan rambut jagung yang merupakan limbah dari budidaya jagung terbatas sebagai obat ...
Ismizana Jati Prasiddha, Rosalina Ariesta Laeliocattleya, Teti Estiasih, Jaya Mahar Maligan   +3 more
doaj  

Metabolic Reprogramming of T Cells by Dual UCP2 and IL‐17 Blockade Enhances Immunity Against Pancreatic Cancer

Advanced Science, EarlyView.
This study demonstrates that dual UCP2/IL‐17 blockade reprograms T‐cell metabolism to overcome PDAC immunosuppression. Genipin‐mediated UCP2 inhibition enhances CD8⁺ T‐cell IFN‐γ via IL‐12R/STAT4/mTOR signaling and mitochondrial OXPHOS. Combined IL‐17 depletion amplifies Tc1/Th1 responses, reduces MDSCs, and prolongs survival in PDAC models ...
Chuan‐Teng Liu, Chun‐Chieh Yeh, Tsai‐Chen Wu, Chia‐Hsin Lin, Yi‐Ting Kuo, Yoichiro Iwakura, Yuan‐Ji Day, Charles Drake, Vedran Radojcic, Ying‐Chyi Song, Heng‐Hsiung Wu, Hung‐Rong Yen   +11 more
wiley   +1 more source

DualPG‐DTA: A Large Language Model‐Powered Graph Neural Network Framework for Enhanced Drug‐Target Affinity Prediction and Discovery of Novel CDK9 Inhibitors Exhibiting in Vivo Anti‐Leukemia Activity

Advanced Science, EarlyView.
This study introduces DualPG‐DTA, a framework integrating two pre‐trained models to generate molecular and protein representations. It constructs dual graphs processed by specialized neural networks with dynamic attention for feature fusion, achieving superior benchmark performance.
Yihao Chen, Jindi Huang, Cong Liu, Shipeng Zhang, Xinze Li, Zhang Zhang, Tie‐Gen Chen, Ling Wang   +7 more
wiley   +1 more source

GLUL Confers Perivascular Cancer‐Associated Fibroblasts With Pro‐Angiogenic Capacity to Promote Glioma Progression

Advanced Science, EarlyView.
Schematic illustration of the proposed model. Primary CAFs are isolated from fresh human GBM specimens according to established protocols. GLUL is essential for pro‐angiogenic capacity of CAFs through its impact on the PI3K/AKT pathway. GLUL enhances the pro‐angiogenic capacity of CAFs, driving aberrant tumor vasculature that fuels tumor growth ...
Qing Zhang, Yida Liu, Zhi Zhang, Yang Wang, Fusheng Liu   +4 more
wiley   +1 more source

Fibrates Inhibit PLTP‐induced M2 Macrophage Infiltration and Increase the Sensitivity of Hepatocellular Carcinoma to ICIs

Advanced Science, EarlyView.
Phospholipid transfer protein(PLTP) plays a critical role in forming a complex with kinase A (AURKA) and P65. This interaction facilitates phosphorylation of P65 at Ser536, leading to the activation of the NF‐κB signaling pathway. Ultimately, this leads to the upregulation of downstream cytokines, including IL‐6, IL‐8, and CSF‐1, which promotes M2 ...
Xinyue Liang, Yaning Li, Jianxun Cai, Lisi Luo, Pengfei Yang, Yutong Chen, Jiancong Zhou, Yan Zeng, Jiaping Yu, Weiyu Zhang, Wenzheng Pang, Yufang Li, Chunhua Wen, Jian Li, Linjuan Zeng   +14 more
wiley   +1 more source

A Hybrid Machine Learning Based Intrusion Detection System for MIL-STD-1553

Havacılık ve Uzay Teknolojileri Dergisi
MIL-STD-1553 is a communication standard developed by the US Department of Defense in 1975, primarily utilized in military aircraft, ground vehicles, and spacecraft.
Yunus Emre Çiloğlu, Şerif Bahtiyar
doaj  

Consumers Preferences to Sweet Potato Flakes (Spf) from Sweet Potato Pasta as A Raw Material, with Enrichment Mung Bean Flour as Source Protein

, 2014
Noveria Sjafrina, Syarifah Aminah
openalex   +2 more sources

Model Problem Based Learning Berbasis Audio Visual Terhadap Kemampuan Berpikir Kritis Dan Motivasi Belajar Peserta Didik UPT SPF SD Negeri Mangkura I Kota Makassar

, 2023
Sunarsi Sunarsi, Muhammad Yunus, Sundari Hamid   +2 more
openalex   +2 more sources

A Modular Vaccine Platform Against SARS‐CoV‐2 Based on Self‐Assembled Protein Nanoparticles

Advanced Science, EarlyView.
A modular BP26 nanoparticle vaccine platform incorporating the SpyTag/SpyCatcher system enables high‐density, repetitive antigen display with post‐expression flexibility. Conjugation of the SARS‐CoV‐2 RBD to BP26 nanoparticles elicits strong humoral immunity and confers protection against viral challenge in vivo.
Seojung Lee, Yejin Jang, Yujin Kim, Yumi Shin, Ji‐Joon Song, Meehyein Kim, Sangyong Jon   +6 more
wiley   +1 more source

From negligible to giant electrocaloric effect of poly(vinylidene fluoride). [PDF]

Nat Commun
Zhang Y, Ye Z, Niu F, Xiong C, Wang W, Fu Y, Zhang S, Wang S, Yang Q, Qin H, Liu S, Wang Q.   +11 more
europepmc   +1 more source