Results 101 to 110 of about 313,761 (243)
Molecular Oncology, EarlyView.Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park +6 more
wiley +1 more source
Molecular Oncology, EarlyView.LUNAR is a liver‐specific long noncoding RNA (lncRNA) that is highly expressed in normal liver but becomes epigenetically silenced in hepatocellular carcinoma through promoter hypermethylation. Loss of LUNAR is associated with NOTCH activation, epithelial–mesenchymal transition, and metastasis, whereas restoring LUNAR restrains metastatic progression ...
Se Ha Jang +9 more
wiley +1 more source
Molecular Oncology, EarlyView.This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi +6 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
تصمیم حاسوبي لعدسة كھروستاتیكیة ثلاثیة الأقطاب
مجلة كلية التربية للبنات, 2019 A low aberration electrostatic lens of three electrode was design, The electrode shapes were determined using solution of Laplace equation . A new Computational technique were used to design an electrostatic lens which depends on the determination ...
أ.د.سمیر خضر العاني ندى عبد الفتاح محمد
doaj
Received 11 October 2023, Revised 21 February 2024, Accepted 1 March 2024, Available online 11 March 2024, Version of Record 16 May 2024. 2023 Acuerdos transformativos CRUE-CSICBackground: To assess accommodation and spherical aberration changes during ...
Batres Valderas, Laura +3 more
core +1 more source
Correcting ocular spherical aberration with soft contact lenses.
, 2004 NoFollowing aberroscopy, aspheric front surface soft contact lenses (SCLs) were custom-made to correct spherical refractive error and ocular spherical aberration (SA) of 18 myopic and five hypermetropic subjects (age, 20.5 . 5 yr).
Cox, Michael J., Dietze, Holger H.
core +1 more source
Molecular Oncology, EarlyView.Loss of NAPRT promotes lung tumor initiation and growth through a noncanonical mechanism, independent of its role in NAD+ biosynthesis. Mechanistically, NAPRT depletion activates the mTORC2‐driven AKT/β‐catenin signaling axis to enhance clonogenic and invasive phenotypes. Furthermore, lung‐specific Naprt deletion significantly increases tumor burden in
Myung Joon Oh +11 more
wiley +1 more source
Effect of cataract incision type on corneal spherical aberration. [PDF]
Medicine (Baltimore), 2022 Li X +6 more
europepmc +1 more source
On the importance of fifth-order spherical aberration for a fully corrected electron microscope.
, 2006 Next generation aberration correctors will not only eliminate the third-order spherical aberration, but also improve the information limit by correction of chromatic aberration.
Chang, LY, Kirkland, AI, Titchmarsh, JM
core +1 more source