Results 141 to 150 of about 343,323 (262)

Connectome analysis of male world-class gymnasts using probabilistic multishell, multitissue constrained spherical deconvolution tracking. [PDF]

J Neurosci Res, 2021
Tomita H, Kamagata K, Andica C, Uchida W, Fukuo M, Waki H, Sugano H, Tange Y, Mitsuhashi T, Lukies M, Hagiwara A, Fujita S, Wada A, Akashi T, Murata S, Harada M, Aoki S, Naito H.   +17 more
europepmc   +1 more source

Synthesis‐Dependent Grain Boundary Density Governs Low‐Temperature Lithium Diffusion in Single‐Crystal NCM Cathodes

Advanced Science, EarlyView.
The relationship between synthesis‐dependent crystallization behavior, internal grain‐boundary density, and intrinsic lithium diffusion kinetics in single‐crystal mid‐Ni NCM cathodes is elucidated, providing practical design insights for advanced cathode materials.
Yeong Beom Kim, Jaewon Lee, Jihong Park, Seunghyeon Chae, Dohyung Kim, Gigap Han, Hyeongi Song, Jihye Jang, Jihoon Choi, Sang Mun Jeong, Yun Chan Kang, Gi Dae Park   +11 more
wiley   +1 more source

[Fiber direction estimation using constrained spherical deconvolution based on multi-model response function]. [PDF]

Sheng Wu Yi Xue Gong Cheng Xue Za Zhi, 2022
Pan Y, Wang Y.
europepmc   +1 more source

Multi‐Technique Integration Identifies O‐GlcNAc Transferase in Fibroblast‐Like Synoviocytes as a Therapeutic Target for Rheumatoid Arthritis

Advanced Science, EarlyView.
AI‑guided single‑cell transcriptomics identifies OGT as a key regulator enriched in rheumatoid arthritis fibroblast‑like synoviocytes (RA‐FLSs). Inflammatory stimuli activate the OGT–SAP130 axis, which modulates the H3K27ac/H3K27me3 balance and epigenetically silences BTG2, promoting aggressive transformation of RA‑FLSs.
Duoli Xie, Jie Huang, Chunhao Cao, Zhenchao Tang, Xingchen Li, Jianmin Guo, Xinxin Chen, Fang Wang, Dongyi He, Jie Li, Yu Du, Bing He, Jianhua Yao, Aiping Lu, Chao Liang   +14 more
wiley   +1 more source

Single‐Molecule Imaging of Endogenous RNA Using a Miniaturized and Circularly Permuted CRISPR‐Cas13 Degron‐Masking System CDegSR

Advanced Science, EarlyView.
CDegSR, a new tool for imaging RNA at single molecule level in living cells was developed by researchers. Background noise was eliminated by protein engineering and making it degrade when not bound to its target. This allowed individual RNA molecules to be clearly imaged and tracked.
Shipeng Shao, Hongchen Zhang
wiley   +1 more source

FOXP1 Knockdown Reprograms Th9 CAR‐T Cells to Overcome Antigen Escape

Advanced Science, EarlyView.
FOXP1 knockdown enhances Th9 CAR‐T cell function by promoting IL‐9 production, effector activation, and reduced exhaustion. Reprogrammed Th9 CAR‐T cells strengthen direct tumor killing and activate endogenous antitumor immunity through dendritic cells and CD8+ T cells, thereby suppressing both antigen‐positive and antigen‐loss tumor growth and ...
Yihan Zhu, Xingwei Xie, Xiaohuan Wu, Suidong Ouyang, Yang Zhou, Kang Wen, Yutong Zhong, Yuyang Chen, Handuo Wang, Yuan Gao, Ling Jiang, Hui Li, Wenli Zhao, Abai Xu, Enguang Bi   +14 more
wiley   +1 more source

Molecular Glue Degraders Enhance CAPRIN1‐Dependent Lysosomal Degradation of APP and Reduce Amyloid β in Alzheimer's Disease

Advanced Science, EarlyView.
A new class of lysosome‐directed molecular glue degraders selectively enhance CAPRIN1–APP interactions, driving APP degradation and reducing amyloid‐β production in human neurons and Alzheimer's disease mouse models. This CAPRIN1‐dependent targeted protein degradation strategy reveals a previously unrecognized therapeutic approach for disrupting the ...
Sunghan Jung, Xu Wang, Bin Liu, Raktim Roy, Nancy Jaiswal, Ratan K. Rai, Yuichiro Takagi, Cen Gao, Lifan Zeng, Ho‐Yin Lo, Reagan K. Wohlford, Ryan K. Higgins, Bruce T. Lamb, Anantha Shekhar, Anita C. Bellail, Chunhai Hao   +15 more
wiley   +1 more source

Sharp minimaxity and spherical deconvolution for super-smooth error distributions

The spherical deconvolution problem was first proposed by Rooij and Ruymgaart (in: G. Roussas (Ed.), Nonparametric Functional Estimation and Related Topics, Kluwer Academic Publishers, Dordrecht, 1991, pp. 679-690) and subsequently solved in Healy et al.
Kim, Peter T., Koo, Ja-Yong, Park, Heon Jin   +2 more
core  

LINEAR DISCRETE CONVOLUTION AND ITS INVERSE. PART 1. CONVOLUTION [PDF]

We present here several ways of calculating the linear discrete convolution, its inverse - the deconvolution, by direct methods, generator functions, Z-transform, using matrices and MATLAB.
Mircea Cirnu
core  

Biosynthesis of Spatially Differentiated Cellulose for Flexible All‐in‐one Supercapacitors

Advanced Science, EarlyView.
Spatially differentiated bacterial cellulose is grown by oxygen‐guided biosynthesis to form dense surface regions connected by an open fibrillar interlayer. This architecture supports electroactive material loading, ion transport, and mechanical stability in an all‐in‐one supercapacitor, showing how biological assembly can create device‐ready ...
Xin Shu, Yi Lu, Xuetong Shi, Zhangmin Wan, Peijin Jiang, Minke Yang, Qingshi Tu, Orlando J. Rojas   +7 more
wiley   +1 more source