Results 51 to 60 of about 343,323 (262)

Magnetic resonance tractography based on the constrained spherical deconvolution in patients with gliomas of the optic pathway

Alʹmanah Kliničeskoj Mediciny, 2021
Background: The use of magnetic resonance (MR) tractography in neurosurgery is becoming an increasingly common practice for noninvasive imaging of white matter pathways.
A. A. Baev, E. L. Pogosbekian, N. E. Zakharova, D. I. Pitskhelauri, A. I. Batalov, A. M. Shkatova, E. I. Shults, A. E. Bykanov, S. A. Maryashev, T. A. Konakova, I. N. Pronin   +10 more
doaj   +1 more source

Variational semi-blind sparse deconvolution with orthogonal kernel bases and its application to MRFM [PDF]

, 2014
We present a variational Bayesian method of joint image reconstruction and point spread function (PSF) estimation when the PSF of the imaging device is only partially known.
Se Un Parka, Hero, Alfred O., Park, Se Un, Dobigeon, Nicolas, Alfred O. Heroa, Nicolas Dobigeonb   +5 more
core   +1 more source

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Improved Constrained Spherical Deconvolution for Microstructural Imaging of Brain Gray Matter

Chinese Journal of Magnetic Resonance
In diffusion magnetic resonance imaging (dMRI), conventional multi-shell constrained spherical deconvolution (CSD) methods usually model white matter microstructure as anisotropic and gray matter microstructure as isotropic.
YANG Jiacheng, WANG Yuanjun
doaj   +1 more source

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

The role of the hippocampus in statistical learning and language recovery in persons with post stroke aphasia

NeuroImage: Clinical, 2022
Although several studies have aimed for accurate predictions of language recovery in post stroke aphasia, individual language outcomes remain hard to predict.
Klara Schevenels, Laura Michiels, Robin Lemmens, Bert De Smedt, Inge Zink, Maaike Vandermosten   +5 more
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

Molecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Delineation of the visual pathway in paediatric optic pathway glioma patients using probabilistic tractography, and correlations with visual acuity

NeuroImage: Clinical, 2018
Background: Radiological biomarkers which correlate with visual function are needed to improve the clinical management of optic pathway glioma (OPG) patients.
Patrick W. Hales, Victoria Smith, Deepi Dhanoa-Hayre, Patricia O'Hare, Kshitij Mankad, Felice d'Arco, Jessica Cooper, Ramneek Kaur, Kim Phipps, Richard Bowman, Darren Hargrave, Christopher Clark   +11 more
doaj   +1 more source

Scanning probe microscopy characterization of immobilized enzyme molecules on a biosensor surface: Visualisation of individual molecules [PDF]

Journal of the Serbian Chemical Society, 2004
Scanning probe microscopy techniques were used to study immobilized enzyme molecules of glucose oxidase (GOD) on a biosensor surface. The study was carried out in order to optimize atomic force microscopy (AFM) imaging and reveal themolecular resolution ...
Lošić Dušan, Short Ken, Gooding Justin J., Shapter Joe G.   +3 more
doaj   +1 more source