Results 51 to 60 of about 433,625 (268)

A History of mathematics and the previous knowledge of teachers as grants for planning a course on geometry ball and hyperbolic

Amazônia, 2014
The aim of this research was to study how the historical development of mathematics, with the backdrop of the evolution of geometry, can assist in the continuing education of mathematics’ teachers.
Wanderley Pivatto Brum
doaj   +1 more source

Spheroidal geometry approach to fullerene molecules

, 2007
Graphite is an example of a layered material that can be bent to form fullerenes which promise important applications in electronic nanodevices. The spheroidal geometry of a slightly elliptically deformed sphere was used as a possible approach to ...
Abrikosov, Birrell, Carroll, Chancey, Decamp, DiVincenzo, González, González, Hou, Jackiw, Kane, Kim, Kobayashy, Kroto, Lozovik, Maas, Mizorogi, Nakahara, Nelson, Osipov, Osipov, Osipov, Pincak, R. Pincak   +23 more
core   +1 more source

A methionine‐lined active site governs carbocation stabilization and product specificity in a bacterial terpene synthase

FEBS Letters, EarlyView.
This study reveals a unique active site enriched in methionine residues and demonstrates that these residues play a critical role by stabilizing carbocation intermediates through novel sulfur–cation interactions. Structure‐guided mutagenesis further revealed variants with significantly altered product profiles, enhancing pseudopterosin formation. These
Marion Ringel, Carl P. O. Helmer, Shani Zev, Ronja Driller, Emily Buhr, Markus Reinbold, Renana Schwartz, Gabriel Foley, Mikael Boden, Daniel Garbe, Gerhard Schenk, Dan Thomas Major, Bernhard Loll, Thomas Brück   +13 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Assessing the Accuracy of 2‐D Planetary Evolution Models Against the 3‐D Sphere

Geochemistry, Geophysics, Geosystems
Regardless of the steady increase of computing power during the last decades, numerical models in a 3D spherical shell are only used in specific setups to investigate the thermochemical convection in planetary interiors, while 2D geometries are typically
A. Fleury, A.‐C. Plesa, C. Hüttig, D. Breuer   +3 more
doaj   +1 more source

Predicting performance of naïve migratory animals, from many wrongs to self-correction

Communications Biology, 2022
A model is developed for assessing compass-based naïve animal migration, revealing effects of spherical geometry on migratory performance, and related mechanisms of self-correction.
James D. McLaren, Heiko Schmaljohann, Bernd Blasius   +2 more
doaj   +1 more source

Synthetic Landau levels and spinor vortex matter on Haldane spherical surface with magnetic monopole

, 2017
We present a flexible scheme to realize exact flat Landau levels on curved spherical geometry in a system of spinful cold atoms. This is achieved by Floquet engineering of a magnetic quadrupole field. We show that a synthetic monopole field in real space
Guo, Guang-Can, Pu, Han, Wang, Ruquan, Wu, Congjun, Zhou, Xiang-Fa, Zhou, Zheng-Wei   +5 more
core   +1 more source

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

Molecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala, Sini Ahonen, Sara Peltola, Aura Tuohisto‐Kokko, Olaya Esparta, Peppi Suominen, Anne Jokilammi, Iman Farahani, Deepankar Chakroborty, Nikol Dibus, Steffen Boettcher, Tomi T. Airenne, Mark S. Johnson, Lisa D. Eli, Klaus Elenius, Kari J. Kurppa   +15 more
wiley   +1 more source

Sustainable bioplastics manufacturing from renewable sources

FEBS Open Bio, EarlyView.
Bioplastics are manufactured by using polymers from different bio‐based sources. These novel materials not only offer biodegradability but also possess various functional properties that make them suitable for diverse applications. Recent developments in the preparation of bioplastics are reported, highlighting the distinct properties of each type of ...
C. Valeria L. Giosafatto, Marika Avitabile, Michela Famiglietti, Talayeh Kordjazi, Marzieh Moosavi‐Nasab, Odile F. Restaino, Loredana Mariniello   +6 more
wiley   +1 more source

Spherical vs. Plane Lenses for Enhanced DUV-LED Performance and Wine Aging

Applied Sciences
The strategic selection of lens geometry—spherical versus plane—decisively shapes the opto-thermal performance boundary of deep ultraviolet light-emitting diodes (DUV-LEDs), thereby governing their efficacy in application-specific photochemical processes.
Jichen Shen, Tianqi Wu, Jun Zou, Peng Wu, Yitao Liao   +4 more
doaj   +1 more source