Results 51 to 60 of about 7,739 (202)

Microconfined flow behavior of red blood cells by image analysis techniques [PDF]

, 2014
This paper was presented at the 4th Micro and Nano Flows Conference (MNF2014), which was held at University College, London, UK. The conference was organised by Brunel University and supported by the Italian Union of Thermofluiddynamics, IPEM, the ...
4th Micro and Nano Flows Conference (MNF2014), Cassinese, A, Guido, S, Lanotte, L, Tomaiuolo, G   +4 more
core  

Yield of Whole Genome Sequencing for Pathogenic Single Nucleotide Variants in Congenital Heart Disease: A Systematic Review and Meta‐Analysis

Prenatal Diagnosis, EarlyView.
ABSTRACT Objective This systematic review and meta‐analysis aimed to assess the diagnostic yield of pathogenic or likely pathogenic (P/LP) single nucleotide variants (SNVs) using whole genome sequencing (WGS) in congenital heart disease (CHD). Methods A systematic search of three databases (2000–2024) was conducted, and two reviewers independently ...
Hiba J. Mustafa, Parisa Najjariasl, Faezeh Aghajani, Enaja V. Sambatur, Andrew Rodenbarger, Stephanie Guseh, Amy E. Roberts, Alireza A. Shamshirsaz   +7 more
wiley   +1 more source

Hereditary spherocytosis with successful splenectomy in a pregnant black South African lady: a case report

The Pan African Medical Journal, 2019
Hereditary spherocytosis is a rare cause of chronic haemolytic anaemia. It is rarer in the black population with extremely few cases reported. Initial assessment of a patient with suspected disease should include documenting clinical features of chronic ...
Khaled Elmezughi, Chukwuma Ekpebegh
doaj   +1 more source

In‐depth analysis of osmotic gradient ektacytometry parameters across different genotypes in hereditary spherocytosis

British Journal of Haematology, EarlyView.
Summary Hereditary spherocytosis (HS) is a hereditary haemolytic anaemia, caused by pathogenic variants in genes encoding red blood cell membrane proteins. Osmotic gradient ektacytometry evaluates red cell deformability and hydration and is increasingly used in the diagnosis of HS.
Jonathan R. A. de Wilde, Geoffrey Z. L. Kuppens, Maryse E. Boesveld, Annelies J. van Vuren, Wouter W. van Solinge, Esmé Waanders, Eduard J. van Beers, Minke A. E. Rab, Marije Bartels, Richard van Wijk   +9 more
wiley   +1 more source

The association between inflammatory markers in routine blood counts at 1 year and attention‐deficit/hyperactivity disorder (ADHD): A case–control study

Journal of Child Psychology and Psychiatry, EarlyView.
Background Attention‐deficit/hyperactivity disorder (ADHD) is a chronic neurodevelopmental disorder marked by persistent patterns of inattention, disorganization, hyperactivity, and impulsivity. Increasing evidence implicates immune‐inflammatory processes in its etiology, with observed associations between ADHD and infectious diseases, allergic ...
Eugene Merzon, Ariel Israel, Shelly Salminis‐Linzen, Eli Magen, Akim Geishin, Shlomo Vinker, Ilan Green, Avivit Golan‐Cohen, Shai Ashkenazi, Stephen V. Faraone, Abraham Weizman, Iris Manor   +11 more
wiley   +1 more source

Paroxysmal Nocturnal Haemoglobinuria‐Associated Acute Cutaneous Thrombosis and Haemolysis in the Setting of Parvovirus B19 and Varicella Zoster Virus Infection

eJHaem, Volume 7, Issue 2, April 2026.
ABSTRACT A 28‐year‐old male with paroxysmal nocturnal haemoglobinuria (PNH) presented with headache, nasal bridge discomfort and haemoglobinuria. He developed a macular‐papular rash which rapidly progressed into purpura, necrosis and peri‐orbital oedema. Investigations demonstrated severe haemolytic anaemia and acute parvovirus B19 infection.
Louise J. Potter, Roochi Trikha, Shreyans Gandhi, Joanne Large, Tanya N. Basu, Jeanne Boissiere, Hannah Devine, Taku Sugai, Aushna Rasool, Austin Kulasekararaj   +9 more
wiley   +1 more source

Disorders of the erythrocyte membrane

Italian Journal of Medicine, 2015
Hemolytic anemia due to abnormalities of the erythrocyte membrane comprises an important group of inherited disorders. These include hereditary spherocytosis, hereditary elliptocytosis, hereditary pyropoikilocytosis, and the hereditary stomatocytosis ...
Sophia Delicou, Aikaterini Xydaki, Chryssanthi Kontaxi, Konstantinos Maragkos   +3 more
doaj   +1 more source

Predicting optimal hematocrit in silico [PDF]

, 2018
Optimal hematocrit $H_o$ maximizes oxygen transport. In healthy humans, the average hematocrit $H$ is in the range of 40-45$\%$, but it can significantly change in blood pathologies such as severe anemia (low $H$) and polycythemia (high $H$). Whether the
Audemar, Vassanti, Benyoussef, Abdelilah, Coupier, Gwennou, Ez-Zahraouy, Hamid, Farutin, Alexander, Harting, Jens, Misbah, Chaouqi, Podgorski, Thomas, Polack, Benoit, Prado, Gael, Shen, Zaiyi, Vlahovska, Petia M.   +11 more
core   +7 more sources

Long‐Term Outcomes of Extrahepatic Portal Vein Obstruction—A Nationwide Registry‐Based Follow‐Up Study From 1987 to 2023

Liver International, Volume 46, Issue 4, April 2026.
ABSTRACT Background and Aims Extrahepatic portal vein obstruction (EHPVO) is among the main causes of childhood portal hypertension. We analysed nationwide long‐term outcomes of EHPVO in relation to various management options. Methods In total, 62 consecutive patients with EHPVO diagnosed between 1987 and 2023 were followed up through hospital records ...
Topi Luoto, Maria Hukkinen, Mikko P. Pakarinen   +2 more
wiley   +1 more source

Clinical and hematologic features of 300 patients affected by hereditary spherocytosis grouped according to the type of the membrane protein defect

Haematologica, 2008
Background Hereditary spherocytosis is a very heterogeneous form of hemolytic anemia. The aim of this study was to relate the type of molecular defect with clinical and hematologic features and response to splenectomy using information from a large ...
Mariagabriella Mariani, Wilma Barcellini, Cristina Vercellati, Anna Paola Marcello, Elisa Fermo, Paola Pedotti, Carla Boschetti, Alberto Zanella   +7 more
doaj   +1 more source