Results 261 to 270 of about 130,558 (351)

Correction: From spheroids to organoids: next-generation models for CAR-T cell therapy research in solid tumors [PDF]

Mégane Jassin, AnneMarie W. Block, Laury Désiront, Louise Vrancken, Céline Grégoire, Frédéric Baron, Grégory Ehx, Thi Tham Nguyen, Jo Caers   +8 more
openalex   +1 more source

Allogeneic Immune Cell Perfusion Inhibits the Growth of Vascularized 3D In Vitro Tumor Models, Induces Vascular Regression and Desmoplasia, but Promotes Tumor Cell Invasion

Advanced Science, EarlyView.
This study presents a vascularized 3D tumor model to investigate immune–stromal–tumor interactions under allogeneic PBMC perfusion. While immune cells induced tumor shrinkage, they also promoted vascular regression, stromal activation, and cancer cell invasion.
Alexandra Raab, Rasika Daware, Marcelo A. Szymanski de Toledo, Oskar Weber, Dimitris Kapsokalyvas, Twan Lammers, Horst Fischer, Federica De Lorenzi, Fabian Kiessling   +8 more
wiley   +1 more source

Correction: Matriptase drives dissemination of ovarian cancer spheroids by a PAR-2/PI3K/Akt/MMP9 signaling axis. [PDF]

J Cell Biol
Pawar NR, Buzza MS, Duru N, Strong AA, Antalis TM.   +4 more
europepmc   +1 more source

Magnesium Structure‐Function Integration Platform for Spatiotemporal Multi‐Modality Therapy: Combining Hormonotherapy and Immunotherapy in Prostate Cancer

Advanced Science, EarlyView.
The schematic illustration of the MHSCG platform for spatiotemporal responsive GRb1 release to induce androgen deprivation therapy (ADT) and immunogenic cell death (ICD) multimodal therapy in prostate cancer. Abstract Metal‐based immunotherapy represents a promising strategy for enhancing antitumor efficacy; however, its clinical application is limited
Rui Zan, Qianping Mao, Keyi Wang, Guodong Zou, Shi Yang, Hua Qiu, Xiang Fang, Guiqing Wang, Xinyi Zhou, Jiexia Wen, Shuai Jiang, Ran Huang, Qiuming Peng, Tao Suo   +13 more
wiley   +1 more source

<i>In vitro</i> model of human subcutaneous adipocyte spheroids for studying mitochondrial dysfunction and mitochondria activating compounds. [PDF]

iScience
Wagner A, Lautaoja-Kivipelto JH, Pehkonen K, Hassinen A, Kuusela M, Röttger L, Herbers E, Ioannidou A, Mädler S, Rothenaigner I, Srinivasan S, Laasonen S, Rahman MT, Elomaa P, Kortetjärvi S, Olsson A, Ukkola O, Hadian K, Mann M, Peltoniemi H, Pietiläinen KH, Klingenspor M, Virtanen KA, Hagberg CE, Pirinen E.   +24 more
europepmc   +1 more source

Blood-brain-barrier spheroids as an in vitro screening platform for brain-penetrating agents

, 2017
David Calligaris, Kalvis Hornburg, E. Antonio Chiocca, Nathalie Y.R. Agar, Sean Lawler, Choi‐Fong Cho, Justin M. Wolfe, Colin M. Fadzen, Bradley L. Pentelute   +8 more
openalex   +1 more source

Osmotic Tension Asymmetry Drives Electrotactic Migration via PDLIM7‐Polarized Microfilament Coordination in Breast Cancer Cells

Advanced Science, EarlyView.
This study establishes an electric field‐induced directional migration model using fluorescence tension probes to visualize microfilament forces and intracellular osmotic pressure dynamics in the electrotactic migration of breast cancer cells. This model delineates how electromechanical interactions among membrane potential, ion channels, OP, traction ...
Ling Zhu, Zihui Zheng, Wang Li, Chenyi Shou, Ying Zhao, Lijun Zhang, Xiaoli Shi, Yunfeng Hu, Huanhuan Zhao, Huiwen Wu, Jun Guo   +10 more
wiley   +1 more source

Temporal metric spaces in radiative transfter theory. III. Characteristic spheroids and ellipsoids

, 1959
Rudolph W Preisendorfer
openalex   +1 more source

OCIAD2 Stabilizes Integrin β1 Signaling Through SNX17‐Mediated Endosomal Recycling to Lipid Rafts and Modulates Cisplatin Response in HNSCC

Advanced Science, EarlyView.
This study identifies OCIAD2 as a critical regulator of cisplatin resistance in HNSCC. Mechanistically, OCIAD2 stabilizes integrin β1 through a direct physical interaction and facilitates its SNX17‐dependent endosomal recycling to lipid raft microdomains. Targeting OCIAD2 disrupts integrin β1 trafficking and significantly enhances cisplatin sensitivity,
Li Cui, Shanshan Si, Min Ye, Pei Lin, Meiyan Zou, Yunfan Lin, Xu Chen, Bing Guo, Wenjuan Sun, Xinyuan Zhao   +9 more
wiley   +1 more source