Results 21 to 30 of about 10,663 (235)

Sphingolipid activator proteins

Biomedicine and Pharmacotherapy, 1989
exaly   +2 more sources

Multiplexed Host-Induced Gene Silencing of Aspergillus flavus Genes Confers Aflatoxin Resistance in Groundnut

Toxins, 2023
Aflatoxins are immunosuppressive and carcinogenic secondary metabolites, produced by the filamentous ascomycete Aspergillus flavus, that are hazardous to animal and human health.
Kalyani Prasad, Kalenahalli Yogendra, Hemalatha Sanivarapu, Kanniah Rajasekaran, Jeffrey W. Cary, Kiran K. Sharma, Pooja Bhatnagar-Mathur   +6 more
doaj   +1 more source

Diverse Sphingolipid Species Harbor Different Effects on Ire1 Clustering [PDF]

, 2022
Endoplasmic reticulum (ER) function is dedicated to multiple essential processes in eukaryotes, including the processing of secretory proteins and the biogenesis of most membrane lipids.
Steuart, Robert F. L., Christopher M. Witham, Bieniawski, Mark A., Stevens, Kofi L.P., Bankaitis, Vytas A., Stevens, Kofi L. P., Mark A. Bieniawski, Vytas A. Bankaitis, Bankaitis, V.A., Witham, Christopher M., Robert F. L. Steuart, Kofi L. P. Stevens, Mousley, Carl J., Carl J. Mousley   +13 more
core   +1 more source

Disorders of Sphingolipid Synthesis, Sphingolipidoses, Niemann-Pick Disease Type C and Neuronal Ceroid Lipofuscinoses [PDF]

, 2022
International audienceSphingolipids are ubiquitous lipids found in all mammalian cell membranes and in plasma lipoproteins. Many exhibit dual functions, as key structural elements, but also as modulators of biological/physiological functions ...
Caillaud, Catherine, Vanier, Marie, Levade, Thierry   +2 more
core   +1 more source

A prosaposin-derived Peptide alleviates kainic Acid-induced brain injury. [PDF]

PLoS ONE, 2015
Four sphingolipid activator proteins (i.e., saposins A-D) are synthesized from a single precursor protein, prosaposin (PS), which exerts exogenous neurotrophic effects in vivo and in vitro.
Hiroaki Nabeka, Tetsuya Shimokawa, Takuya Doihara, Shouichiro Saito, Hiroyuki Wakisaka, Fumihiko Hamada, Naoto Kobayashi, Seiji Matsuda   +7 more
doaj   +1 more source

β-Hexosaminidase B and Sphingolipid Activator Proteins [PDF]

, 2004
Titelblatt Inhaltsverzeichnis Zusammenfassung Danksagung Abkürzungen 1 Einleitung 1 1.1 Erbliche Stoffwechselstörungen 1 1.2 Glykosphingolipide 3 1.3 Glykosphingolipid ...
Maier, Timm
core   +1 more source

Membrane-spanning lipids for an uncompromised monitoring of membrane fusion and intermembrane lipid transfer

Journal of Lipid Research, 2015
A Förster resonance energy transfer-based fusion and transfer assay was developed to study, in model membranes, protein-mediated membrane fusion and intermembrane lipid transfer of fluorescent sphingolipid analogs.
Günter Schwarzmann, Bernadette Breiden, Konrad Sandhoff   +2 more
doaj   +1 more source

Selective reduction of bis(monoacylglycero)phosphate ameliorates the storage burden in a THP-1 macrophage model of Gaucher disease

Journal of Lipid Research, 2013
Bis(monoacylglycero)phosphate (BMP) assists lysosomal function by facilitating interaction of hydrolases and activator proteins with sphingolipid substrates.
Leanne K. Hein, Stephen Duplock, Maria Fuller   +2 more
doaj   +1 more source

Role of endosomal membrane lipids and NPC2 in cholesterol transfer and membrane fusion[S]

Journal of Lipid Research, 2010
We examined the effect of Niemann-Pick disease type 2 (NPC2) protein and some late endosomal lipids [sphingomyelin, ceramide and bis(monoacylglycero)phosphate (BMP)] on cholesterol transfer and membrane fusion.
Misbaudeen Abdul-Hammed, Bernadette Breiden, Matthew A. Adebayo, Jonathan O. Babalola, Günter Schwarzmann, Konrad Sandhoff   +5 more
doaj   +1 more source

Degradation of blood group A glycolipid A-6-2 by normal and mutant human skin fibroblasts

Journal of Lipid Research, 1998
The degradation of blood group glycolipid A-6-2 (GalNAc(α1→3)[Fucα1→2]Gal(β1→4)GlcNAc(β1→3)Gal (β1→4)Glc(β1→1′)Cer, IV2-α-fucosyl-IV3-α-N-acetylgalactosaminylneolactotetraosylceramide), tritium-labeled in its ceramide moiety, was studied in situ, in skin
Befekadu Asfaw, Detlev Schindler, Jana Ledvinová, Bohuslav Černý, František Šmíd, Ernst Conzelmann   +5 more
doaj   +1 more source