Results 231 to 240 of about 81,593 (273)

Correction: Chlamydia trachomatis Co-opts GBF1 and CERT to Acquire Host Sphingomyelin for Distinct Roles during Intracellular Development

open access: gold, 2013
Cherilyn A. Elwell   +7 more
openalex   +2 more sources

A Global Metabolomic and Lipidomic Landscape of Human Plasma Across the Lifespan

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
Liu et al. provide a comprehensive analysis of dynamic plasma metabolomic and lipidomic changes in humans across the lifespan, identifying age‐specific metabolic trajectories and developing a metabolite‐based aging clock, offering insights into metabolic reprogramming and potential biomarkers for aging‐related health interventions.
Xinru Liu   +6 more
wiley   +1 more source

Sphingomyelins of Local Fat Depots and Blood Serum as Promising Biomarkers of Cardiovascular Diseases [PDF]

open access: diamond
E. V. Belik   +6 more
openalex   +1 more source

Downregulation of BST2 Rescues Cochlear Nerve Demyelination in Age‐Related Hearing Loss via Enhancing Schwann Cell Migration

open access: yesAging Cell, Volume 25, Issue 1, January 2026.
The illustration indicates that increased BST2 expression in Schwann cells leads to cochlear nerve demyelination, accelerating hearing loss in ARHL. The upregulation of BST2 reduces POU6F1 expression by activating the NF‐κB pathway, which impairs MPZ transcription and Schwann cell migration, ultimately contributing to neural demyelination in ARHL ...
Mengxiao Liu   +8 more
wiley   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

open access: yesBrain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li   +7 more
wiley   +1 more source

Lipidomic profiling unveils sex differences in diabetes risk: Implications for precision medicine

open access: yesEuropean Journal of Clinical Investigation, Volume 56, Issue 1, January 2026.
This study uncovered sex‐specific metabolic and lipidomic signatures of prediabetes. In PREVADIAB2 (n = 953), clustering by insulin traits revealed four phenotypes. Lipidomics showed women enriched in dihydroceramides and sphingomyelins, while men displayed a higher ceramide/sphingomyelin ratio. These sex‐metabolic phenotypes expose distinct lipidomes,
Ana F. Pina   +8 more
wiley   +1 more source

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