Results 141 to 150 of about 42,462 (262)

Coupled plagioclase dissolution and K‐feldspar overgrowth precipitation preserve anomalously high permeability in deeply buried sandstones

open access: yesSedimentology, EarlyView.
ABSTRACT This study investigated the formation mechanism responsible for anomalously high permeability (AHP) observed in the Eocene sandstones at depths from 3824 to 3832 m in the Huizhou Sag, Pearl River Mouth Basin, China, using helium porosity and permeability measurements, thin section, scanning electron microscopy, electron probe X‐ray ...
Changgui Xu   +12 more
wiley   +1 more source

Fucosylation limits ADCC in clinically used anti‐RhD monoclonal antibodies

open access: yesTransfusion, EarlyView.
Abstract Background Haemolytic disease of the fetus and newborn (HDFN) is caused by maternal alloantibodies, often targeting the D antigen on fetal red blood cells. Maternal immunization is preventable with timely administration of anti‐D polyclonal antibodies (pAbs).
Gabriela Koike   +33 more
wiley   +1 more source

The sickling pressure index predicts hemoglobin S target achievement during chronic red cell exchange in sickle cell disease

open access: yesTransfusion, EarlyView.
Abstract Background Chronic automated red cell exchange (RCE) reduces hemoglobin S (HbS) in patients with sickle cell disease (SCD), but procedural success varies across patients in ways standard exchange parameters do not explain. We introduce the Sickling Pressure Index (SPI), derived from each patient's daily rate of HbS rise (ROR) and daily rate of
Austin Choi   +3 more
wiley   +1 more source

Warburg redefined: Metabolites, mitochondria and macrophages in immune regulation

open access: yesThe Journal of Physiology, EarlyView.
Abstract figure legend Following pro‐inflammatory stimulation, macrophages undergo Warburg‐like metabolic rewiring that extends more than increased glycolysis. The non‐canonical functions of glycolytic enzymes and lactate accumulation control macrophage immune responses through multiple signalling pathways (a).
Yukun Min   +2 more
wiley   +1 more source

sox17 Mutagenesis Reveals Compounding Effects ofMaternal and Zygotic Contribution on Microglia Abundance

open access: yesGlia, Volume 75, Issue 1, January 2027.
sox17 is a maternal effect gene impacting microglia and microglia precursor abundance. sox17 mRNA injection timed to maternal contribution rescues abundance. A CRISPR screen reveals f11r.1, gas6, and mpp1 also regulate microglia abundance. ABSTRACT Embryonic development is shaped by maternal and zygotic factors but how the interplay between these ...
Camden A. Spring   +4 more
wiley   +1 more source

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